{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,22]],"date-time":"2026-08-22T16:37:29Z","timestamp":1787416649694,"version":"build-2736575974"},"reference-count":21,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,1,12]],"date-time":"2026-01-12T00:00:00Z","timestamp":1768176000000},"content-version":"vor","delay-in-days":11,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Glucagon\u2010like peptide\u20101 receptor agonists (GLP\u20101 RAs) have gained rapid popularity for both medical and consumer\u2010directed weight loss. This growth has been accompanied by increased public discussion regarding facial aesthetic changes, commonly referred to as \u201cOzempic face,\u201d characterized by volume depletion and cutaneous laxity.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To quantify temporal patterns of public search interest in a widely known GLP\u20101 RA and evaluate corresponding awareness of its cosmetic facial sequelae using infodemiologic methods.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Google Trends data for \u201cOzempic\u201d and related frequently co\u2010searched queries were analyzed from November 2021 to December 2024. Trends in relative search volume (RSV) were examined, with particular focus on terms associated with facial aesthetics, including \u201cOzempic face\u201d and \u201cplastic surgeons Ozempic face.\u201d<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>RSV for \u201cOzempic\u201d showed a steady upward trajectory over the study period. Queries related to facial aesthetic consequences exhibited substantial proportional increases. Notably, \u201cOzempic face\u201d demonstrated a 4600% rise in RSV, and searches for \u201cplastic surgeons Ozempic face\u201d similarly grew markedly.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Public interest in GLP\u20101 RAs is strongly associated with rising awareness and concern about their facial aesthetic effects. These trends suggest that aesthetic practitioners should expect more patient inquiries regarding GLP\u20101\u2013related facial changes and should proactively integrate counseling and corrective treatment options into clinical practice.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jocd.70670","type":"journal-article","created":{"date-parts":[[2026,1,12]],"date-time":"2026-01-12T08:13:36Z","timestamp":1768205616000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Rising Public Interest in Weight Loss Medications and Growing Awareness of Their Aesthetic Sequelae: An Infodemiologic Google Trends Analysis and Clinical Diagnostic Patterning"],"prefix":"10.1111","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5063-5413","authenticated-orcid":false,"given":"Alec D.","family":"McCarthy","sequence":"first","affiliation":[{"name":"Global Medical Affairs Merz Aesthetics  Raleigh North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-1287-8619","authenticated-orcid":false,"given":"Kay","family":"Durairaj","sequence":"additional","affiliation":[{"name":"K. Kay Durairaj, M.D., A Medical Corp  Pasadena California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-4348-4711","authenticated-orcid":false,"given":"Jacob","family":"Linneman\u2010Heath","sequence":"additional","affiliation":[{"name":"Global Medical Affairs Merz Aesthetics  Raleigh North Carolina USA"},{"name":"K. Kay Durairaj, M.D., A Medical Corp  Pasadena California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dusan","family":"Sajic","sequence":"additional","affiliation":[{"name":"Derma Skin Institute  Guelph Ontario Canada"},{"name":"McMaster University  Hamilton Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0999-4278","authenticated-orcid":false,"given":"Mara","family":"Dacso","sequence":"additional","affiliation":[{"name":"Innovative Dermatology  Plano Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1675-9519","authenticated-orcid":false,"given":"Alan","family":"Durkin","sequence":"additional","affiliation":[{"name":"Ocean Drive Plastic Surgery, Dermatology, and MedSpa  Vero Beach Florida USA"},{"name":"Florida State University College of Medicine  Tallahassee Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,1,12]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.japh.2023.10.002"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jval.2024.03.2316"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11154\u2010021\u201009699\u20101"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/der2.70003"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/asj\/sjae132"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.3389\/fdata.2023.1132764"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.envint.2018.05.016"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/asj\/sjab084"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.52011"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.1101\/2024.01.18.24301500"},{"key":"e_1_2_13_12_1","doi-asserted-by":"publisher","DOI":"10.1177\/0145445516673998"},{"key":"e_1_2_13_13_1","doi-asserted-by":"publisher","DOI":"10.2196\/47620"},{"key":"e_1_2_13_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/jocd.16216"},{"key":"e_1_2_13_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/asj\/sjad173"},{"key":"e_1_2_13_16_1","doi-asserted-by":"publisher","DOI":"10.1177\/1090820X13515270"},{"key":"e_1_2_13_17_1","doi-asserted-by":"publisher","DOI":"10.1080\/147641704100003048"},{"key":"e_1_2_13_18_1","doi-asserted-by":"publisher","DOI":"10.2147\/CCID.S72878"},{"key":"e_1_2_13_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/ohn.1209"},{"key":"e_1_2_13_20_1","doi-asserted-by":"publisher","DOI":"10.1093\/asjof\/ojaf088"},{"key":"e_1_2_13_21_1","doi-asserted-by":"publisher","DOI":"10.1097\/DSS.0000000000004659"},{"key":"e_1_2_13_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/jocd.70094"}],"container-title":["Journal of Cosmetic Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocd.70670","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jocd.70670","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocd.70670","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,24]],"date-time":"2026-01-24T04:16:05Z","timestamp":1769228165000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jocd.70670"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":21,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["10.1111\/jocd.70670"],"URL":"https:\/\/doi.org\/10.1111\/jocd.70670","archive":["Portico"],"relation":{},"ISSN":["1473-2130","1473-2165"],"issn-type":[{"value":"1473-2130","type":"print"},{"value":"1473-2165","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"2025-06-25","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-12-18","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-01-12","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70670"}}