{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T23:00:30Z","timestamp":1783119630531,"version":"3.54.6"},"reference-count":37,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,4,9]],"date-time":"2026-04-09T00:00:00Z","timestamp":1775692800000},"content-version":"vor","delay-in-days":8,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100005706","name":"Beijing Technology and Business University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005706","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study aims to evaluate the effects of Fish Collagen Peptide Nutritional Combination (FCPNC) on facial skin rejuvenation and biochemical indicators, including body mass index (BMI), blood lipids, superoxide dismutase (SOD), and bone mineral density in participants.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This study involved 29 female participants aged 20\u201355\u2009years, who consumed FCPNC daily for 90\u2009days. Facial skin changes, including wrinkle percentage, pigmentation area, skin hydration, and elasticity, were assessed before and after the intervention. Additionally, BMI, blood tests, and bone mineral density were measured on Day 0 and Day 90. Participants completed questionnaires on skin, nails, hair, and product satisfaction at Days 30, 60, and 90.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>After 30, 60, and 90\u2009days, participants exhibited significant improvements in skin hydration, elasticity, and a reduction in wrinkle area percentage. This nutritional combination not only improved skin health but also yielded systemic benefits, including normalizing BMI in 58.33% of overweight participants. SOD activity increased by 31.03%, reflecting enhanced antioxidant capacity. Additionally, calcium levels rose by 48.28%, suggesting potential bone health benefits. Satisfaction surveys revealed increasing positive feedback, with 93% of participants rating the product favorably by the study's conclusion (score\u2009\u2265\u20094).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>These findings suggest that FCPNC may positively influence skin health and overall health status, emphasizing its potential as a functional food. However, further large\u2010scale randomized controlled trials are necessary to validate these results.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jocd.70841","type":"journal-article","created":{"date-parts":[[2026,4,9]],"date-time":"2026-04-09T07:45:21Z","timestamp":1775720721000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Oral Fish Collagen Peptide Complex Enhances Skin Rejuvenation and Systemic Health Biomarkers: A 90 Day Prospective Observational Study"],"prefix":"10.1111","volume":"25","author":[{"given":"Jingjing","family":"Huang","sequence":"first","affiliation":[{"name":"School of Light Industry Science and Engineering Beijing Technology and Business University  Beijing China"},{"name":"Beijing Key Laboratory of Plant Resource Research and Development Beijing Technology and Business University  Beijing 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