{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,13]],"date-time":"2026-06-13T03:00:44Z","timestamp":1781319644885,"version":"3.54.1"},"reference-count":24,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T00:00:00Z","timestamp":1779235200000},"content-version":"vor","delay-in-days":19,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Xanthelasma palpebrarum (XP) is a common cutaneous condition of the eyelid, which compromises eyelid aesthetics. Non\u2010surgical treatments are often limited by multiple sessions and high cost. Surgical treatment, although effective, is constrained by the limited availability of eyelid skin and the risk of ectropion. A simple, safe, and effective therapeutic technique is essential for managing XP.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>This study aimed to present a new dermatologic treatment for XP and assess its effectiveness.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A novel technique, punch\u2010assisted xanthelasma nucleus excision (PAXNE), was applied in four cases of mild\u2010to\u2010moderate XP (Grades I and II) under local anesthesia. Clinical photographs of the patients at the preoperative and postoperative follow\u2010up for 1\u2009month were recorded. Treatment outcomes were assessed at a 1\u2010month follow\u2010up using a 5\u2010Likert scale for periorbital aesthetics and patient satisfaction. Additionally, two independent physicians evaluated treatment efficacy based on lesion clearance (0\u20134 Scale).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Postoperative scarring was inconspicuous, and aesthetic outcomes were satisfactory at the 1\u2010month follow\u2010up. After 1\u2010month follow\u2010up, the average 5\u2010Likert scale score for periorbital aesthetics was 3.25, and the average patient satisfaction score was 3.75. The objective treatment efficacy score reached 4.0 for all cases, indicating over 75% clearance of the lesions. No postoperative complications, such as eyelid ectropion, were found in the preliminary series.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>PAXNE is a promising, minimally invasive approach showing excellent short\u2010term aesthetic results, but it needs more investigation in larger cohorts with long\u2010term follow\u2010up.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jocd.70940","type":"journal-article","created":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T07:06:12Z","timestamp":1779260772000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Novel and Simple Punch Treatment for Xanthelasma Palpebrarum: A Preliminary Case Series"],"prefix":"10.1111","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-0226-4287","authenticated-orcid":false,"given":"Hui","family":"Cheng","sequence":"first","affiliation":[{"name":"Department of Plastic Surgery The First Affiliated Hospital of Anhui Medical University  Hefei Anhui China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wende","family":"Yao","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery The First Affiliated Hospital of Anhui Medical University  Hefei Anhui China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yun","family":"Bai","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery The First Affiliated Hospital of Anhui Medical University  Hefei Anhui China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-5403-4432","authenticated-orcid":false,"given":"Xinyi","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery The First Affiliated Hospital of Anhui Medical University  Hefei Anhui China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2609-0572","authenticated-orcid":false,"given":"Xiaojing","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery The First Affiliated Hospital of Anhui Medical University  Hefei Anhui China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,5,20]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.5507\/bp.2014.016"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00403\u2010024\u201002863\u2010y"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.Prs.0000025626.70065.2b"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.5999\/aps.2013.40.4.380"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/gox.0000000000004982"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/jocd.13678"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10103\u2010024\u201004273\u2010y"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/ijd.16475"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00266\u2010013\u20100195\u20100"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2017.03.041"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.2147\/ccid.S130116"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1055\/s\u20100029\u20101245829"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537\u2010198409000\u201000019"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo\u20102024\u2010325581"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2025.03.024"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1089\/photob.2020.4874"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1080\/09546634.2020.1775776"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-197611000-00001"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00266\u2010024\u201004435\u2010x"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.31729\/jnma.7485"},{"key":"e_1_2_12_22_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2024.1347112"},{"key":"e_1_2_12_23_1","doi-asserted-by":"publisher","DOI":"10.1097\/dad.0000000000002514"},{"key":"e_1_2_12_24_1","doi-asserted-by":"publisher","DOI":"10.5826\/dpc.1404a218"},{"key":"e_1_2_12_25_1","doi-asserted-by":"publisher","DOI":"10.1097\/dss.0000000000003078"}],"container-title":["Journal of Cosmetic Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocd.70940","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jocd.70940","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocd.70940","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,13]],"date-time":"2026-06-13T02:50:43Z","timestamp":1781319043000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jocd.70940"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5]]},"references-count":24,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,5]]}},"alternative-id":["10.1111\/jocd.70940"],"URL":"https:\/\/doi.org\/10.1111\/jocd.70940","archive":["Portico"],"relation":{},"ISSN":["1473-2130","1473-2165"],"issn-type":[{"value":"1473-2130","type":"print"},{"value":"1473-2165","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5]]},"assertion":[{"value":"2025-08-10","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-15","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-20","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70940"}}