{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T10:37:41Z","timestamp":1760783861460,"version":"3.37.3"},"reference-count":43,"publisher":"Wiley","issue":"1-2","license":[{"start":{"date-parts":[[2014,9,25]],"date-time":"2014-09-25T00:00:00Z","timestamp":1411603200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100012553","name":"Chang Gung Memorial Hospital","doi-asserted-by":"crossref","award":["CMRPG350991"],"award-info":[{"award-number":["CMRPG350991"]}],"id":[{"id":"10.13039\/100012553","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Clinical Nursing"],"published-print":{"date-parts":[[2015,1]]},"abstract":"<jats:sec><jats:title>Aims<\/jats:title><jats:p>This study was designed to evaluate the efficacy of an aerobic exercise programme on fatigue for Taiwanese breast cancer women under radiotherapy (RT).<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>Cancer\u2010related fatigue has been widely reported by patients undergoing radiotherapy as strongly and profoundly interfering with their quality of life. Evidence has shown that exercise can be beneficial to patients with breast cancer.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>A quasi\u2010experimental design was used.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients with early\u2010stage breast cancer scheduled for radiotherapy were invited to participate. The first 28 women who agreed to participate were assigned to the intervention group with a six\u2010week mild\u2010 to moderate\u2010intensity aerobic exercise training programme during their radiotherapy. The next 30 women were assigned to the routine care control group without special exercise intervention. Fatigue was measured at pre\u2010radiotherapy and weekly after starting radiotherapy for six weeks using the Taiwanese version of the Brief Fatigue Inventory.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The mean age of these 47 women was 50\u00b73\u00a0years (standard deviation\u00a0=\u00a09\u00b75). The baseline fatigue severity for the intervention group and control group were 3\u00b704 and 2\u00b795 respectively; and the baseline fatigue interference for the intervention group and the control group were 3\u00b748 and 3\u00b755 respectively. The student <jats:italic>t<\/jats:italic>\u2010test showed no group differences in baseline fatigue severity, fatigue interference, or haemoglobin levels. Multivariate analyses showed a significant group\u2010by\u2010time\u2010interaction effect for fatigue severity and interference (<jats:italic>p\u00a0<\/jats:italic>\u2266\u00a00\u00b7001); the fatigue severity and interference decreased significantly over time for women in the intervention group but increased over time for women in the control group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The mild\u2010 to moderate\u2010intensity aerobic exercise programme reduces the fatigue of Taiwanese women with breast cancer undergoing radiotherapy. The issues of cancer\u2010related fatigue should also be discussed as they relate to other treatment modalities.<\/jats:p><\/jats:sec><jats:sec><jats:title>Relevance to clinical practice<\/jats:title><jats:p>Aerobic exercise intervention should be offered as an option for women with breast cancer to alleviate cancer\u2010related fatigue when undergoing radiotherapy.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jocn.12672","type":"journal-article","created":{"date-parts":[[2014,9,25]],"date-time":"2014-09-25T06:08:01Z","timestamp":1411625281000},"page":"202-211","source":"Crossref","is-referenced-by-count":14,"title":["Effects of an aerobic exercise programme on fatigue for patients with breast cancer undergoing radiotherapy"],"prefix":"10.1111","volume":"24","author":[{"given":"Tsui\u2010Yun","family":"Yang","sequence":"first","affiliation":[{"name":"Graduate Institute of Nursing National Taipei University of Nursing and Health Science and Instructor School of Nursing, College of Medicine Chang Gung University Taoyuan Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mei\u2010Ling","family":"Chen","sequence":"additional","affiliation":[{"name":"School of Nursing, College of Medicine Chang Gung University Taoyuan Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chia\u2010Chun","family":"Li","sequence":"additional","affiliation":[{"name":"School of Nursing, College of Medicine Chang Gung University Taoyuan Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,9,25]]},"reference":[{"volume-title":"Breast Cancer Facts & Figures 2013\u20132014","year":"2013","author":"American Cancer Society","key":"e_1_2_12_2_1"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2005.07.024"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.3816\/CBC.2008.n.064"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/00002820-200509000-00008"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1249\/00005768-198205000-00012"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005768-200212000-00001"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1188\/05.ONF.237-240"},{"key":"e_1_2_12_9_1","unstructured":"Cancer Control Team Health Promotion Administration (HPA) Taiwan ROC. 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