{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T03:21:45Z","timestamp":1781839305489,"version":"3.54.5"},"reference-count":36,"publisher":"Wiley","issue":"11-12","license":[{"start":{"date-parts":[[2017,3,20]],"date-time":"2017-03-20T00:00:00Z","timestamp":1489968000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003453","name":"Natural Science Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["2014A030313785"],"award-info":[{"award-number":["2014A030313785"]}],"id":[{"id":"10.13039\/501100003453","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Clinical Nursing"],"published-print":{"date-parts":[[2017,6]]},"abstract":"<jats:sec><jats:title>Aim<\/jats:title><jats:p>To investigate whether a nurse\u2010led care was more beneficial for implementing chronic kidney disease guidelines and improved multiple risk factors compared with the usual care.<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>Several independent clinical trials have been carried out to demonstrate the efficiency of a nurse\u2010led care to improve the outcomes for patients with chronic kidney disease and address the risk factors for renal function decline. However, their results and conclusions were inconsistent.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A meta\u2010analysis was carried out on September 2015 based on previous studies that evaluated the efficiency of nurse\u2010led care model for patients with chronic kidney disease. Following quality appraisal, four randomised clinical trials that allocated patients with chronic kidney disease to usual care and nurse\u2010coordinated care were included. Primary outcomes, such as kidney failure and cardiovascular events, were analysed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Compared with the usual care group, a nurse\u2010coordinated care model reduced the risks of composite death, decreased the occurrence rate of end\u2010stage renal disease and doubled serum creatinine. On the contrary, a slight propulsive effect of nurse\u2010led interventional care occurred on acute myocardial infarction and heart failure.<\/jats:p><\/jats:sec><jats:sec><jats:title>Limitations<\/jats:title><jats:p>Only five studies were included and conducted nonstandard evaluating endpoints, causing fewer studies were categorised in each outcome events in this meta\u2010analysis, subsequently leading to heterogeneity and less persuasive.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Intensive interventions delivered by nurse coordinators are expected to benefit patients to attain longer life expectancy and higher life quality as well as to improve controlling risk factors implicated in chronic kidney disease progression.<\/jats:p><\/jats:sec><jats:sec><jats:title>Relevance to clinical practice<\/jats:title><jats:p>More government and hospitals should modify the traditional nursing routine based on this study, providing a more intensive nurse\u2010coaching care model for patients with chronic kidney disease, even aged or other chronic diseases, which shall further help to better control the risk factors and delay disease progression.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jocn.13533","type":"journal-article","created":{"date-parts":[[2016,8,23]],"date-time":"2016-08-23T05:52:45Z","timestamp":1471931565000},"page":"1639-1649","source":"Crossref","is-referenced-by-count":25,"title":["A nurse\u2010coordinated model of care versus usual care for chronic kidney disease: meta\u2010analysis"],"prefix":"10.1111","volume":"26","author":[{"given":"Haidan","family":"Xu","sequence":"first","affiliation":[{"name":"Shenzhen Domesticated Organ Medical Engineering Research and Development Center Shenzhen Second People's Hospital First Affiliated Hospital of Shenzhen University Shenzhen China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisha","family":"Mou","sequence":"additional","affiliation":[{"name":"Shenzhen 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