{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,21]],"date-time":"2025-09-21T17:22:38Z","timestamp":1758475358248,"version":"3.37.3"},"reference-count":43,"publisher":"Wiley","issue":"23-24","license":[{"start":{"date-parts":[[2017,10,8]],"date-time":"2017-10-08T00:00:00Z","timestamp":1507420800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Clinical Nursing"],"published-print":{"date-parts":[[2017,12]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>To investigate the independent predictors of medication adherence among Singaporean patients following an ischaemic stroke or transient ischaemic attack.<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>Secondary prevention of stroke includes optimal control over modifiable risk factors, and medication adherence is important in controlling the effect of comorbidities. However, there is a paucity of published literature on the topics of medication adherence among stroke patients, especially in the Asian population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>A cross\u2010sectional, descriptive, correlational study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>One hundred and twenty\u2010one patients with ischaemic stroke or transient ischaemic attack were recruited from a tertiary hospital in Singapore. Data collection included the Morisky Medication Adherence Scale\u20108 (<jats:styled-content style=\"fixed-case\">MMAS<\/jats:styled-content>\u20108), General Self\u2010Efficacy Survey (<jats:styled-content style=\"fixed-case\">GSES<\/jats:styled-content>) and Medical Outcome Study Social Support Survey. Multiple linear regression analyses were used to evaluate predictors of medication adherence, measured by <jats:styled-content style=\"fixed-case\">MMAS<\/jats:styled-content>\u20108.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The mean score of the <jats:styled-content style=\"fixed-case\">MMAS<\/jats:styled-content>\u20108 was 5.07 (<jats:italic>SD<\/jats:italic>\u00a0=\u00a02.20, range 0\u20138), and more than 80% of the participants had low (<jats:italic>n\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>65, 53.7%) or medium (<jats:italic>n\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>34, 28.1%) levels of medication adherence. Multivariate linear regression analysis showed that two factors, namely \u201cunderstanding the benefits of medications\u201d (\u03b2\u00a0=\u00a00.238, <jats:italic>p\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>.010) and \u201chaving suffered from stroke twice or more\u201d (\u03b2\u00a0=\u00a00.235, <jats:italic>p\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>.014), were identified as independent predictors of medication adherence in stroke patients while the other variables were adjusted. These two factors accounted for 12.4% of the variance.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Medication adherence was poor in Singaporean patients following an ischaemic stroke or transient ischaemic attack. The independent predictors identified in this study will support healthcare professionals to develop tailored intervention to improve medication adherence among this group of patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Relevance to clinical practice<\/jats:title><jats:p>Nurses play an important role in promoting patients\u2019 medication adherence. Helping stroke patients understand the long\u2010term benefits of their medications is essential to enhance patients\u2019 medication adherence and results in better health outcomes.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jocn.14001","type":"journal-article","created":{"date-parts":[[2017,8,9]],"date-time":"2017-08-09T21:02:55Z","timestamp":1502312575000},"page":"5016-5024","source":"Crossref","is-referenced-by-count":10,"title":["Independent predictors of medication adherence among Singaporean patients following an ischaemic stroke or transient ischaemic attack"],"prefix":"10.1111","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0265-8215","authenticated-orcid":false,"given":"Wenru","family":"Wang","sequence":"first","affiliation":[{"name":"Alice Lee Centre for Nursing Studies Yong Loo Lin School of Medicine National University of Singapore Singapore Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gerk Sin","family":"Chia","sequence":"additional","affiliation":[{"name":"Tan Tock Seng Hospital Singapore Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Il Fan","family":"Tan","sequence":"additional","affiliation":[{"name":"National Neuroscience Institute Singapore Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Siew Noi Janis","family":"Tye","sequence":"additional","affiliation":[{"name":"National Neuroscience Institute Singapore Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaona","family":"Wang","sequence":"additional","affiliation":[{"name":"Tan Tock Seng Hospital Singapore Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Birong","family":"Zhu","sequence":"additional","affiliation":[{"name":"Tan Tock Seng Hospital Singapore Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ying","family":"Jiang","sequence":"additional","affiliation":[{"name":"Alice Lee Centre for Nursing Studies Yong Loo Lin School of Medicine National University of Singapore Singapore Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,10,8]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.4103\/0028-3886.32783"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40266-014-0212-2"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2011.06.007"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.4065\/mcp.2010.0575"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e31822f0423"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.mrr.0000127640.55118.6b"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1037\/0033-2909.112.1.155"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.108.534487"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.113.000251"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/ageing\/afn282"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1037\/0278-6133.23.2.207"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.2217\/ahe.11.43"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjopharm.2011.02.004"},{"issue":"4","key":"e_1_2_10_15_1","first-page":"7","article-title":"Medication adherence post\u2010stroke: An exploratory study of stroke unit nurses\u2019 perspectives of potential problems affecting patients early after discharge","volume":"9","author":"Gibson J. 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