{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T21:12:13Z","timestamp":1785618733015,"version":"3.56.0"},"reference-count":39,"publisher":"Wiley","issue":"9-10","license":[{"start":{"date-parts":[[2018,5,27]],"date-time":"2018-05-27T00:00:00Z","timestamp":1527379200000},"content-version":"vor","delay-in-days":26,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100007225","name":"Ministry of Science and Technology","doi-asserted-by":"publisher","award":["104\u20102314\u2010B\u2010255\u2010001"],"award-info":[{"award-number":["104\u20102314\u2010B\u2010255\u2010001"]}],"id":[{"id":"10.13039\/100007225","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Clinical Nursing"],"published-print":{"date-parts":[[2018,5]]},"abstract":"<jats:sec><jats:title>Aims and objectives<\/jats:title><jats:p>To investigate the distribution and risk factors associated with undiagnosed obstructive sleep apnoea among hypertensive patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>Obstructive sleep Apnoea has been deemed a cardinal risk factor affecting cardiovascular event, and the condition is still frequently overlooked clinically. The lack of advanced diagnosis often causes hypertensive patients with obstructive sleep apnoea to miss opportunities for preventing chronic diseases.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>A cross\u2010sectional design.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 215 hypertensive participants were recruited from the cardiovascular outpatients of medical centre in northern and middle Taiwan. The Chinese version of Pittsburgh Sleep Quality Index, the Chinese version of the Epworth Sleep Scale and a portable sleep monitoring device were used for data collection. Logistic regression analysis was conducted to identify the factors affecting hypertensive patients with obstructive sleep apnoea, and a multinomial logistic regression analysis was used to examine the major influence factors for each obstructive sleep apnoea severity level.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>81.9% of the hypertensive participants were found having obstructive sleep apnoea. Concerning to the obstructive sleep apnoea severity, 50.0% of participants had mild obstructive sleep apnoea. After controlling the confounding variables, the supine position (odds ratio, 1.04; 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>, 1.01\u20131.07), <jats:styled-content style=\"fixed-case\">SO<\/jats:styled-content><jats:sub>2<\/jats:sub> (odds ratio, 0.58; 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>, 0.38\u20130.89) and oxygen desaturation index (odds ratio, 2.70; 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>, 1.18\u20136.18) were significantly associated with obstructive sleep apnoea. Furthermore, severe obstructive sleep apnoea was significantly correlated with gender (odds ratio, 0.04; 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>, 0.00\u20130.66), excessive daytime sleepiness (odds ratio, 20.27; 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>, 1.58\u201326.97) and oxygen desaturation index (odds ratio, 4.05; 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>, 1.86\u20138.81).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Nearly 82% of the hypertensive participants were found having undiagnosed obstructive sleep apnoea, and 80% of them were mild or moderate severity. Oxygen desaturation index, <jats:styled-content style=\"fixed-case\">SO<\/jats:styled-content><jats:sub>2<\/jats:sub> and the supine position were found to be major predictors for obstructive sleep apnoea. Remarkably, oxygen desaturation index was the most significant predictor for mild, moderate and severe obstructive sleep apnoea.<\/jats:p><\/jats:sec><jats:sec><jats:title>Relevance to clinical practice<\/jats:title><jats:p>Healthcare providers should enhance their sensitivities to hypertensive patients at a high risk for obstructive sleep apnoea by actively assessing common obstructive sleep apnoea symptoms and providing strategies to alleviate obstructive sleep apnoea symptoms.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jocn.14366","type":"journal-article","created":{"date-parts":[[2018,3,31]],"date-time":"2018-03-31T11:44:36Z","timestamp":1522496676000},"page":"1901-1912","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Factors associated with undiagnosed obstructive sleep apnoea among hypertensive patients: A multisite cross\u2010sectional survey study in Taiwan"],"prefix":"10.1111","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4466-8075","authenticated-orcid":false,"given":"Hsiu\u2010Chin","family":"Hsu","sequence":"first","affiliation":[{"name":"Department of Graduate Institute of Health Care Chang Gung University of Science and Technology Taipei Taiwan"},{"name":"Department of Internal Medicine Chang Gung Memorial Hospital Tao\u2010Yuan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ning\u2010Hung","family":"Chen","sequence":"additional","affiliation":[{"name":"Taiwan Society of Sleep Medicine Taipei Taiwan"},{"name":"Sleep Center Chang Gung Memorial Hospital Tao\u2010Yuan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wan Jing","family":"Ho","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine Chang Gung Memorial Hospital Tao\u2010Yuan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4188-6413","authenticated-orcid":false,"given":"Mei\u2010Hsiang","family":"Lin","sequence":"additional","affiliation":[{"name":"National Taipei University of Nursing and Health Science Taipei City Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,5,27]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201701-0048UP"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0157318"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.157.1.9706079"},{"issue":"1","key":"e_1_2_11_5_1","first-page":"38","article-title":"Utility of the Berlin Questionnaire to screen for obstructive sleep apnea among patients receiving intravenous sedation for colonoscopy","volume":"82","author":"Boese L.","year":"2014","journal-title":"AANA Journal"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.3109\/02813432.2012.675563"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/0165-1781(89)90047-4"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.289.19.2560"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0b013e318248f4f5"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cardfail.2015.06.009"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0012065"},{"issue":"6","key":"e_1_2_11_12_1","doi-asserted-by":"crossref","first-page":"655","DOI":"10.5664\/jcsm.2258","article-title":"The impact of body posture and sleep stages on sleep apnea severity in adults","volume":"8","author":"Eiseman N. 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