{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T04:41:09Z","timestamp":1783744869080,"version":"3.55.0"},"reference-count":33,"publisher":"Wiley","issue":"19-20","license":[{"start":{"date-parts":[[2021,11,14]],"date-time":"2021-11-14T00:00:00Z","timestamp":1636848000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Clinical Nursing"],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aims and objectives<\/jats:title><jats:p>To compare the safety of replacing peripheral intravenous catheter as clinically indicated versus routine replacement on patient outcomes in the Chinese context.<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>Some evidence from developed countries recommend replacing peripheral intravenous catheter as clinically indicated; however, there is limited evidence from developing countries.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>A multisite randomised controlled trial.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The 3050 participants from three hospitals in China were randomly assigned to clinically indicated or routine replacement groups. Patients in the clinically indicated group had the catheters kept in situ until any of the following clinical signs appeared: phlebitis, infiltration, occlusion, displacement, local infection and diagnosed catheter\u2010related bloodstream infection. Patients in the routine replacement group had their peripheral intravenous catheters replaced every 96\u00a0hours. The outcomes of phlebitis, infiltration, occlusion, displacement; catheter\u2010related bloodstream infection, all\u2010cause bloodstream infection, and local infection were compared. CONSORT checklist was used to guide the reporting of this RCT.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The risk of phlebitis, phlebitis per 1000 catheter days, occlusion, dislodgement, all bloodstream infections, local infection and mortality between the two groups were not significantly different. The risk of infiltration was increased in the clinically indicated group (HR 1.29). There was no catheter\u2010related bloodstream infection reported in either group. Patients\u2019 first peripheral intravenous catheter dwelling time and cumulative indwelling time of all peripheral intravenous catheters in the clinically indicated group were significantly longer than the routine replacement group. There was no statistical significant difference in survival times from phlebitis between the two groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In the Chinese context, removing peripheral catheters as clinical indicated did not increase the risk of phlebitis, occlusion, catheter displacement and catheter infection; however, there was an increased infiltration incidence.<\/jats:p><\/jats:sec><jats:sec><jats:title>Relevance to clinical practice<\/jats:title><jats:p>In developing countries, removing peripheral catheters as clinical indicated is feasible, but more frequent observations of infiltration are highly recommended.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jocn.16129","type":"journal-article","created":{"date-parts":[[2021,11,15]],"date-time":"2021-11-15T04:40:17Z","timestamp":1636951217000},"page":"2959-2970","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Routine replacement versus replacement as clinical indicated of peripheral intravenous catheters: A multisite randomised controlled trial"],"prefix":"10.1111","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5683-466X","authenticated-orcid":false,"given":"Jing","family":"Li","sequence":"first","affiliation":[{"name":"Nursing Department Peking University First Hospital  Xicheng District, Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanming","family":"Ding","sequence":"additional","affiliation":[{"name":"Nursing Department Peking University First Hospital  Xicheng District, Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qian","family":"Lu","sequence":"additional","affiliation":[{"name":"Peking University School of Nursing  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanli","family":"Jin","sequence":"additional","affiliation":[{"name":"Peking University School of Nursing  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peiying","family":"Zhang","sequence":"additional","affiliation":[{"name":"Nursing Department Peking University First Hospital  Xicheng District, Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7044-051X","authenticated-orcid":false,"given":"Zhixia","family":"Jiang","sequence":"additional","affiliation":[{"name":"Guizhou Nursing Vocational College  Guiyang China"},{"name":"Affiliated Hospital of Zunyi Medical College  Zunyi China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fengxia","family":"Zhang","sequence":"additional","affiliation":[{"name":"Miyun Hospital  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3560-4061","authenticated-orcid":false,"given":"Yang","family":"Lyu","sequence":"additional","affiliation":[{"name":"Beijing Chao\u2010Yang Hospital  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8735-5469","authenticated-orcid":false,"given":"Frances","family":"Lin","sequence":"additional","affiliation":[{"name":"School of Nursing, Midwifery, and Paramedicine University of the Sunshine Coast  Queensland Australia"},{"name":"Sunshine Coast Health Institute  Queensland Australia"},{"name":"School of Nursing and Midwifery Menzies Health Institute Queensland Griffith University  Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,11,14]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.12788\/jhm.3039"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1308\/147870804317"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/NAN00000000096"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen\u20102018\u2010028549"},{"issue":"1","key":"e_1_2_12_6_1","first-page":"S1","article-title":"Infusion nursing standards of practice","volume":"39","author":"Infusion Nurses Society","year":"2016","journal-title":"Infusion therapy standards of practice"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12916\u2010020\u201001728\u20101"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/jjns.12328"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1177\/1129729820978124"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1177\/1129729819877323"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.12788\/jhm.2867"},{"key":"e_1_2_12_12_1","first-page":"CD011070.","volume-title":"Devices and dressings to secure peripheral venous catheters to prevent complications. The Cochrane database of systematic reviews","author":"Marsh N.","year":"2015"},{"key":"e_1_2_12_13_1","unstructured":"National Health Commission of People\u2019s Republic of China. (2013).Nursing practice standards for intravenous therapy."},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.4037\/ccn2020439"},{"issue":"2","key":"e_1_2_12_15_1","first-page":"60","article-title":"Does elective re\u2010siting of intravenous cannulae decrease peripheral thrombophlebitis? A randomized controlled study","volume":"22","author":"Nishanth S.","year":"2009","journal-title":"National Medical Journal of India"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/NCQ.0000000000000429"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajic.2020.07.036"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.idh.2019.03.001"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140\u20106736(12)61082\u20104"},{"issue":"36","key":"e_1_2_12_20_1","first-page":"12","article-title":"ANTT: a standard approach to aseptic technique","volume":"107","author":"Rowley S.","year":"2011","journal-title":"Nursing Times"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12879\u2010017\u20102536\u20100"},{"key":"e_1_2_12_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/jocn.14760"},{"key":"e_1_2_12_23_1","doi-asserted-by":"publisher","DOI":"10.12968\/bjon.2010.19.Supl.47079"},{"key":"e_1_2_12_24_1","doi-asserted-by":"publisher","DOI":"10.1097\/NAN.0000000000000281"},{"key":"e_1_2_12_25_1","doi-asserted-by":"publisher","DOI":"10.1086\/599776"},{"key":"e_1_2_12_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijnurstu.2019.103504"},{"key":"e_1_2_12_27_1","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0000000000003393"},{"key":"e_1_2_12_28_1","doi-asserted-by":"publisher","DOI":"10.3969\/j.issn.1006\u20100111.2017.06.023"},{"key":"e_1_2_12_29_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.a339"},{"key":"e_1_2_12_30_1","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD007798.pub5"},{"key":"e_1_2_12_31_1","doi-asserted-by":"publisher","DOI":"10.1111\/ijn.12595"},{"key":"e_1_2_12_32_1","doi-asserted-by":"publisher","DOI":"10.12102\/j.issn.2095\u20108668.2020.06.001"},{"key":"e_1_2_12_33_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.g1262"},{"key":"e_1_2_12_34_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11096\u2010019\u201000898\u20100"}],"container-title":["Journal of Clinical Nursing"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocn.16129","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jocn.16129","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocn.16129","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,22]],"date-time":"2023-08-22T02:05:32Z","timestamp":1692669932000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jocn.16129"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11,14]]},"references-count":33,"journal-issue":{"issue":"19-20","published-print":{"date-parts":[[2022,10]]}},"alternative-id":["10.1111\/jocn.16129"],"URL":"https:\/\/doi.org\/10.1111\/jocn.16129","archive":["Portico"],"relation":{},"ISSN":["0962-1067","1365-2702"],"issn-type":[{"value":"0962-1067","type":"print"},{"value":"1365-2702","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,11,14]]},"assertion":[{"value":"2021-06-21","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-10-27","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-11-14","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}