{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,9]],"date-time":"2026-04-09T03:31:22Z","timestamp":1775705482916,"version":"3.50.1"},"reference-count":52,"publisher":"Wiley","issue":"23-24","license":[{"start":{"date-parts":[[2021,12,12]],"date-time":"2021-12-12T00:00:00Z","timestamp":1639267200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Clinical Nursing"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aims and objectives<\/jats:title><jats:p>Determination of the effect of deep breathing exercise applied with Triflo on dyspnoea, anxiety and quality of life in patients who are hospitalized for COVID\u201019 and have dyspnoea.<\/jats:p><\/jats:sec><jats:sec><jats:title>Backround<\/jats:title><jats:p>COVID\u201019 is a viral infection that can cause severe pulmonary disease. Deep breathing exercise with Triflo in patients with COVID\u201019\u00a0may contribute to the reduction\/elimination of dyspnoea and anxiety, and improvement of respiratory and quality of life.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>The study was a randomized controlled clinical trial and conducted in accordance with the Consolidated Standards of Reporting Trials (CONSORT) 2010 guidelines.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The study was conducted in the clinic of COVID\u201019 of a tertiary hospital. A total of 44 eligible participants were enrolled from January to April 2021. Primary outcomes included oxygen saturation in the blood, respiratory assessment and dyspnoea level. Secondary outcomes included anxiety and quality of life. In the statistical analysis of the data, the independent sample <jats:italic>t<\/jats:italic>\u2010test, Wilcoxon test, Mann\u2013Whitney <jats:italic>U<\/jats:italic> test and Spearman correlation were used to examine the intervention effect on primary outcomes and secondary outcomes, according to numbers, percentage, mean, standard deviation and conformity to normal distribution.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>It was determined that the patients in the deep breathing group had a statistically significant shorter hospitalization time (3.04\u00a0\u00b1\u00a00.65), higher SpO<jats:sub>2<\/jats:sub>\u00a0level (97.05\u00a0\u00b1\u00a01.46) and higher quality of life (77.82\u00a0\u00b1\u00a06.77) compared with the patients in the usual care group (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Deep breathing exercise with Triflo increases the SpO<jats:sub>2<\/jats:sub>\u00a0level and quality of life in patients with COVID\u201019 and contributes to a decrease in dyspnoea and anxiety levels. Moreover, the duration of hospital stay is shortened in patients who are applied deep breathing exercise with Triflo.<\/jats:p><\/jats:sec><jats:sec><jats:title>Relevance to clinical practice<\/jats:title><jats:p>With deep breathing exercise applied with Triflo, respiratory rate reaches normal limits in a short time, SpO<jats:sub>2<\/jats:sub>\u00a0levels increase significantly, and quality of life improves significantly in patients with COVID\u201019 pneumonia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Clinical trials registration number<\/jats:title><jats:p><jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"https:\/\/clinicaltrials.gov\">https:\/\/clinicaltrials.gov<\/jats:ext-link>; NCT04696562.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jocn.16171","type":"journal-article","created":{"date-parts":[[2021,12,13]],"date-time":"2021-12-13T05:39:37Z","timestamp":1639373977000},"page":"3439-3453","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":30,"title":["Effect of deep breathing exercise with Triflo on dyspnoea, anxiety and quality of life in patients receiving covid\u201019 treatment: A randomized controlled trial"],"prefix":"10.1111","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8667-2411","authenticated-orcid":false,"given":"Hatice","family":"\u00d6ner Cengiz","sequence":"first","affiliation":[{"name":"Department of Midwifery Faculty of Nursing Ankara University  Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4821-5559","authenticated-orcid":false,"given":"M\u00fcge","family":"Ayhan","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases and Clinical Microbiology Ankara City Hospital  Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1029-1185","authenticated-orcid":false,"given":"Rahmet","family":"G\u00fcner","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases and Clinical Microbiology Ankara Y\u0131ld\u0131r\u0131m Beyaz\u0131t University Ankara City Hospital  Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,12,12]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.11604\/pamj.supp.2020.37.9.25718"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjsports\u20102020\u2010102596"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/thx.54.7.581"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140\u20106736(20)30154\u20109"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.26355\/eurrev_202005_21213"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096\u20109136(199701)14:1<29:AID\u2010DIA300>3.0.CO;2\u2010V"},{"issue":"2","key":"e_1_2_11_8_1","first-page":"23","article-title":"Psychometric properties of WHOQOL\u2010100 and WHOQOL\u2010BREF","volume":"7","author":"Eser E.","year":"1999","journal-title":"3P Dergisi"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11739\u2010020\u201002355\u20107"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00134\u2010020\u201006033\u20102"},{"issue":"1","key":"e_1_2_11_11_1","first-page":"28","article-title":"Researching of the effectiveness of deep breathing and incentive spirometry in postoperative early stage","volume":"15","author":"Gen\u00e7 A.","year":"2004","journal-title":"Fizyoterapi Rehabilitasyon"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.31125\/hunhemsire.454354"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000021373"},{"key":"e_1_2_11_14_1","doi-asserted-by":"crossref","unstructured":"Jia X. 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