{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T22:03:45Z","timestamp":1791065025074,"version":"4.1.0"},"reference-count":40,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2023,2,17]],"date-time":"2023-02-17T00:00:00Z","timestamp":1676592000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Clinical Nursing"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To determine post\u2010COVID syndromes in the Indian population, correlating a wide spectrum of post\u2010COVID manifestations with acute disease severity and associated risk factors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>Post\u2010COVID Syndrome (PCS) is defined as signs and symptoms that develop during or after acute COVID\u201019 infection.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design of Study<\/jats:title><jats:p>This is a prospective observational cohort with repetitive measurements.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The study followed RT\u2010PCR confirmed COVID\u201019\u2010positive survivors discharged from HAHC Hospital, New Delhi, for a period of 12\u2009weeks. The patients were interviewed over the phone at 4\u2009weeks and 12\u2009weeks from the onset of symptoms for evaluation of clinical symptoms and health\u2010related quality of life parameters.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 200 patients completed the study. At the baseline, 50% of the patients were categorised as severe based on their acute infection assessment. At 12\u2009weeks after symptom onset, fatigue (23.5%), hair loss (12.5%) and dyspnea (9%) were the main persistent symptoms. The incidence of hair loss (12.5%), memory loss (4.5%) and brain fog (5%) were found to be increased as compared to the acute infection period. Severity of the acute COVID infection behaved as an independent predictor for the development of PCS, with high odds of experiencing persistent cough (OR\u00a0=\u00a013.1), memory loss (OR\u00a0=\u00a05.2) and fatigue (OR\u00a0=\u00a03.3). Further, 30% of subjects in the severe group experienced statistically significant fatigue at 12\u2009weeks (<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>From the results of our study, it can be concluded that there is a huge disease burden of post\u2010COVID Syndrome (PCS). The PCS comprised multisystem symptoms ranging from serious complaints of dyspnea, memory loss and brain fog to non\u2010serious complaints of fatigue and hair loss. Severity of the acute COVID infection behaved as an independent predictor for the development of PCS. Our findings strongly recommend vaccination against COVID\u201019, for protection from disease severity as well as prevention of PCS.<\/jats:p><\/jats:sec><jats:sec><jats:title>Relevance to Clinical Practice<\/jats:title><jats:p>The findings of our study support the multidisciplinary approach required for the management of PCS with a team comprising of physicians, nurses, physiotherapists and psychiatrists working in close coordination for the rehabilitation of these patients. As nurses are considered the most trusted professionals in the community and the class of health workers associated with rehabilitation, focus should be given to educating them on PCS, which would prove to be an important strategy for efficient monitoring and long\u2010term management of COVID\u201019 survivors.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jocn.16652","type":"journal-article","created":{"date-parts":[[2023,2,18]],"date-time":"2023-02-18T17:47:06Z","timestamp":1676742426000},"page":"115-125","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Long\u2010term health consequences of <scp>COVID<\/scp>\u201019 in survivors hospitalised at a tertiary care hospital and their correlation with acute <scp>COVID<\/scp>\u201019 severity and associated risk factors"],"prefix":"10.1111","volume":"33","author":[{"given":"Vineet","family":"Jain","sequence":"first","affiliation":[{"name":"Department of Medicine Hamdard Institute of Medical Sciences and Research and associated HAHC Hospital  New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nusrat","family":"Nabi","sequence":"additional","affiliation":[{"name":"Department of Pharmacology Hamdard Institute of Medical Sciences and Research and associated HAHC Hospital  New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanjana","family":"Aggarwal","sequence":"additional","affiliation":[{"name":"Department of Medicine Hamdard Institute of Medical Sciences and Research and associated HAHC Hospital  New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zaara","family":"Alam","sequence":"additional","affiliation":[{"name":"Department of Medicine Hamdard Institute of Medical Sciences and Research and associated HAHC Hospital  New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4938-9622","authenticated-orcid":false,"given":"Kailash","family":"Chandra","sequence":"additional","affiliation":[{"name":"Department of Biochemistry Hamdard Institute of Medical Sciences and Research and associated HAHC Hospital  New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dharmander","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Medicine Hamdard Institute of Medical Sciences and Research and associated HAHC Hospital  New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Varun","family":"Kashyap","sequence":"additional","affiliation":[{"name":"Department of Community Medicine Hamdard Institute of Medical Sciences and Research and associated HAHC Hospital  New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Farzana","family":"Islam","sequence":"additional","affiliation":[{"name":"Department of Community Medicine Hamdard Institute of Medical Sciences and Research and associated HAHC Hospital  New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sunil","family":"Kohli","sequence":"additional","affiliation":[{"name":"Department of Medicine Hamdard Institute of Medical Sciences and Research and associated HAHC Hospital  New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,2,17]]},"reference":[{"key":"e_1_2_13_2_1","unstructured":"AIIMS\/ ICMR\u2010COVID\u201019 National Task Force\/ Joint Monitoring Group. 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