{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T00:19:48Z","timestamp":1789777188674,"version":"4.0.1"},"reference-count":20,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2025,5,20]],"date-time":"2025-05-20T00:00:00Z","timestamp":1747699200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Clinical Nursing"],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To investigate the association between the New Early Warning Score (NEWS) and 28\u2010day mortality in patients with severe fever with thrombocytopenia syndrome (SFTS).<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>A cross\u2010sectional derivation and validation study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 382 SFTS patients were included in retrospective and prospective studies. The primary outcome was short\u2010term (28\u2010day) mortality. Cox regression, receiver operating characteristic (ROC), and Kaplan\u2013Meier analysis were utilised in the retrospective study to assess the association between NEWS and mortality. The prospective study assessed the applicability of the NEWS.<\/jats:p><\/jats:sec><jats:sec><jats:title>Reporting Method<\/jats:title><jats:p>This study was reported in accordance with the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) guidelines.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among 219 SFTS patients in the retrospective study, 27 (12.3%) died within 28\u2009days. NEWS was significantly higher in non\u2010survivors than in survivors (4.00 [1.00, 5.00] vs. 1.00 [1.00, 2.00]). The ROC curve for MEWS predicting 28\u2010day mortality showed an area under the curve (AUC) of 0.757 (95% confidence interval: 0.65\u20130.87), with a cut\u2010off of 3.5 (sensitivity: 90.6%; specificity: 55.6%). SFTS patients were stratified into low (NEWS &lt;\u20094), medium (NEWS 4\u20136), and high (NEWS &gt;\u20096) risk groups. Kaplan\u2013Meier analysis showed significantly lower survival rates in medium and high risk groups compared to the low risk group. The prospective study included 63 SFTS patients, of whom 11 (17.5%) died. 28\u2010day mortality significantly increased across NEWS categories: [low risk (4\/50, 8.0%), medium risk (4\/8, 50.0%), high risk (3\/5, 60.0%)].<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>NEWS was a quicker, simpler, and valuable parameter to identify SFTS patients at risk of 28\u2010day mortality.<\/jats:p><\/jats:sec><jats:sec><jats:title>Relevance to Clinical Practice<\/jats:title><jats:p>An elevated NEWS at admission is associated with a higher risk of poor short\u2010term prognosis in SFTS patients. Incorporating NEWS into emergency nursing practice may aid in the early identification of SFTS patients at risk of adverse prognosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Patient or Public Contribution<\/jats:title><jats:p>Emergency nurses performed the NEWS for the SFTS patients at admission.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jocn.17713","type":"journal-article","created":{"date-parts":[[2025,5,20]],"date-time":"2025-05-20T10:58:21Z","timestamp":1747738701000},"page":"2992-3002","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["The National Early Warning Score (<scp>NEWS<\/scp>) Predicts the 28\u2010Day Mortality in Patients With Severe Fever With Thrombocytopenia Syndrome: A Cross\u2010Sectional Study"],"prefix":"10.1111","volume":"34","author":[{"given":"Tianshu","family":"Mei","sequence":"first","affiliation":[{"name":"Department of Emergency Medicine, Nanjing Drum Tower Hospital The Affiliated Hospital of Nanjing University Medical School  Nanjing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Xia","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Nanjing Drum Tower Hospital The Affiliated Hospital of Nanjing University Medical School  Nanjing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ping","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Nanjing Drum Tower Hospital The Affiliated Hospital of Nanjing University Medical School  Nanjing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yali","family":"Xiong","sequence":"additional","affiliation":[{"name":"Department of Infectious Disease, Nanjing Drum Tower Hospital The Affiliated Hospital of Nanjing University Medical School  Nanjing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yiwen","family":"Weng","sequence":"additional","affiliation":[{"name":"Internal Medicine Department Chengdu Jinniu District People's Hospital  Chengdu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhonghai","family":"Wei","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Nanjing Drum Tower Hospital The Affiliated Hospital of Nanjing University Medical School  Nanjing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3721-198X","authenticated-orcid":false,"given":"Fei","family":"He","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Nanjing Drum Tower Hospital The Affiliated Hospital of Nanjing University Medical School  Nanjing China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,5,20]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0210875"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0211133"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcdd10020060"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/s12276\u2010021\u201000610\u20101"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140\u20106736(18)30696\u20102"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1086\/588660"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejim.2021.12.024"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11739\u2010022\u201003189\u20101"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0005909"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1136\/fmch\u20102023\u2010002239"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12879\u2010022\u201007206\u20108"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.12968\/bjcn.2021.26.8.396"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/ijcp.14121"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/0895\u20104356(88)90132\u20101"},{"key":"e_1_2_11_16_1","unstructured":"Royal College of Physicians.2012.\u201cNational Early Warning Score (NEWS): standardising the assessment of acute illness severity in the NHS. Report of a working party.\u201dAccessed July 29 2021.https:\/\/tinyurl.com\/ex3daf65."},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.3390\/v13071213"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003\u20104819\u2010147\u20108\u2010200710160\u201000010"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12879\u2010016\u20102111\u20100"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12879\u2010022\u201007320\u20107"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.5847\/wjem.j.1920\u20108642.2020.04.002"}],"container-title":["Journal of Clinical Nursing"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocn.17713","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,21]],"date-time":"2025-06-21T03:00:04Z","timestamp":1750474804000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jocn.17713"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,20]]},"references-count":20,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2025,7]]}},"alternative-id":["10.1111\/jocn.17713"],"URL":"https:\/\/doi.org\/10.1111\/jocn.17713","archive":["Portico"],"relation":{},"ISSN":["0962-1067","1365-2702"],"issn-type":[{"value":"0962-1067","type":"print"},{"value":"1365-2702","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,5,20]]},"assertion":[{"value":"2024-06-19","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-02-18","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-05-20","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}