{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,11]],"date-time":"2026-10-11T04:06:24Z","timestamp":1791691584712,"version":"4.3.4"},"reference-count":59,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Clinical Nursing"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims and Objectives<\/jats:title>\n                    <jats:p>To investigate the effects of the Family\u2010Centred Empowerment Model on informal caregivers on individuals with chronic diseases.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The Family\u2010Centred Empowerment Model may help address informal caregivers' challenges in chronic disease management, including caregiver burden. However, its effectiveness for informal caregivers of chronic disease patients remains unclear.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Systematic review and meta\u2010analysis of randomised controlled trials and quasi\u2010experimental studies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The review followed the PRISMA 2020 guidelines. A comprehensive search was conducted in EMBASE, PubMed, Cochrane Library, Web of Science, CINAHL, CNKI, SinoMed and Wanfang Data from their inception to January 2024. Two investigators independently evaluated study quality using the Cochrane Risk of Bias Tool and the Joanna Briggs Institute checklist.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>This review included 22 studies. The meta\u2010analysis demonstrated that the Family\u2010Centred Empowerment Model significantly reduced caregiver burden, stress and anxiety. Subgroup analyses further revealed a positive effect on reducing caregiver burden across both paediatric and adult patient populations. Additionally, the intervention's effect on caregiver burden remained significant for 1\u20133\u2009months following the intervention. While the model did not significantly affect the pooled outcome for care ability, subgroup analyses indicated that the model was more effective at improving care ability 3\u2009weeks post\u2010intervention compared to immediately after the intervention.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The Family\u2010Centred Empowerment Model for informal caregivers of chronic disease patients may help reduce caregiver burden, stress and anxiety, while gradually improving care ability. However, it has no significant effect on depression or family function.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Relevance to Clinical Practice<\/jats:title>\n                    <jats:p>The review provides valuable evidence to guide clinicians in implementing the Family\u2010Centred Empowerment Model for informal caregivers of chronic disease patients. By applying this model, caregivers can reduce burdens, stress and anxiety while enhancing their care abilities.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>No Patient or Public Contribution<\/jats:title>\n                    <jats:p>As a systematic review and meta\u2010analysis, these details did not apply to our work.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial Registration<\/jats:title>\n                    <jats:p>PROSPERO (CRD42024505357)<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jocn.70006","type":"journal-article","created":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T22:54:47Z","timestamp":1751410487000},"page":"602-620","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Effectiveness of the Family\u2010Centred Empowerment Model on Informal Caregivers of People With Chronic Diseases: A Systematic Review and Meta\u2010Analysis"],"prefix":"10.1111","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-5952-4235","authenticated-orcid":false,"given":"Xiao","family":"Lin","sequence":"first","affiliation":[{"name":"Department of Gastrointestinal Surgery Affiliated Hospital of Xuzhou Medical University  Xuzhou City Jiangsu Province China"},{"name":"School of Medical and Health Engineering Changzhou University  Changzhou City Jiangsu Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9246-9775","authenticated-orcid":false,"given":"Fei","family":"Fei","sequence":"additional","affiliation":[{"name":"School of Medical and Health Engineering Changzhou University  Changzhou City Jiangsu Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7877-3746","authenticated-orcid":false,"given":"Xiaohan","family":"Zhang","sequence":"additional","affiliation":[{"name":"Cicely Saunders Institute of Palliative Care, Policy and Rehabilitation, Florence Nightingale Faculty of Nursing, Midwifery &amp; Palliative Care King's College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6421-5647","authenticated-orcid":false,"given":"Yuxin","family":"Zhou","sequence":"additional","affiliation":[{"name":"Cicely Saunders Institute of Palliative Care, Policy and Rehabilitation, Florence Nightingale Faculty of Nursing, Midwifery &amp; Palliative Care King's College London  London UK"},{"name":"Department of Nursing Zhongda Hospital Southeast University  Nanjing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-5322-8687","authenticated-orcid":false,"given":"Fang","family":"Qin","sequence":"additional","affiliation":[{"name":"Cicely Saunders Institute of Palliative Care, Policy and Rehabilitation, Florence Nightingale Faculty of Nursing, Midwifery &amp; Palliative Care King's College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-6935-8619","authenticated-orcid":false,"given":"Xia","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Surgery Affiliated Hospital of Xuzhou Medical University  Xuzhou City Jiangsu Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-6945-046X","authenticated-orcid":false,"given":"Yafei","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Vascular Surgery Affiliated Hospital of Xuzhou Medical University  Xuzhou City Jiangsu Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8513-5681","authenticated-orcid":false,"given":"Jonathan","family":"Koffman","sequence":"additional","affiliation":[{"name":"Hull York Medical School, Wolfson Palliative Care Research Centre University of Hull  Hull UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,7,1]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2014.304"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/JCN.0000000000000816"},{"key":"e_1_2_13_4_1","unstructured":"Alhani F.2003a.\u201cDesign and Evaluation of Family\u2010Centered Empowerment Model to Prevent Iron Deficiency Anemia.\u201dTarbiat Modarres University Tehran."},{"key":"e_1_2_13_5_1","unstructured":"Alhani F.2003b.\u201cEvaluating of Family Centered Empowerment Model on Preventing Iron Deficiency Anemia.\u201dTarbiat Modares University [Dissertation]."},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2022.07.066"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.22038\/EBCJ.2019.14043"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.1080\/17482631.2021.1994804"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.5812\/jjcdc\u2010116854"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.1080\/09638288.2021.1966675"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/jijnurstu.2021.104162"},{"key":"e_1_2_13_12_1","doi-asserted-by":"publisher","DOI":"10.3969\/j.issn.1672\u20107010.2021.05.011"},{"key":"e_1_2_13_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40520\u2010019\u201001321\u20104"},{"key":"e_1_2_13_14_1","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm6907a2"},{"key":"e_1_2_13_15_1","doi-asserted-by":"publisher","DOI":"10.5430\/jnep.v6n11p119"},{"key":"e_1_2_13_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yebeh.2018.08.030"},{"key":"e_1_2_13_17_1","unstructured":"Feng X. Y.2023.\u201cA Study of the Impact of a Family Empowerment Program on the Burden of Care and Social Support for Parents of Children With Cochlear Implants.\u201dShanxi Medical University [Dissertation].https:\/\/doi.org\/10.27288\/d.cnki.gsxyu.2023.001073."},{"key":"e_1_2_13_18_1","doi-asserted-by":"publisher","DOI":"10.19791\/j.cnki.1006\u20106411.2023.28.006"},{"key":"e_1_2_13_19_1","doi-asserted-by":"publisher","DOI":"10.5812\/msnj\u2010134004"},{"key":"e_1_2_13_20_1","doi-asserted-by":"publisher","DOI":"10.4103\/ijnmr.IJNMR_161_19"},{"key":"e_1_2_13_21_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.d5928"},{"key":"e_1_2_13_22_1","doi-asserted-by":"publisher","DOI":"10.37506\/ijfmt.v15i2.15016"},{"key":"e_1_2_13_23_1","doi-asserted-by":"publisher","DOI":"10.32598\/jccnc.7.4.305.3"},{"key":"e_1_2_13_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pecinn.2024.100290"},{"key":"e_1_2_13_25_1","volume-title":"Long Term Care Workforce: Employment and Working Conditions","author":"Lanchy G.","year":"2020"},{"key":"e_1_2_13_26_1","doi-asserted-by":"publisher","DOI":"10.1002\/114651858.CD009660.pub3"},{"key":"e_1_2_13_27_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0282887"},{"key":"e_1_2_13_28_1","doi-asserted-by":"publisher","DOI":"10.1080\/07370016.2023.2276744"},{"key":"e_1_2_13_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.burns.2022.06.002"},{"key":"e_1_2_13_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijnurstu.2023.104504"},{"key":"e_1_2_13_31_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpubh.2023.1115311"},{"key":"e_1_2_13_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140\u20106736(18)31992\u20105"},{"key":"e_1_2_13_33_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12875\u2010022\u201001795\u20108"},{"key":"e_1_2_13_34_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.n71"},{"key":"e_1_2_13_35_1","doi-asserted-by":"publisher","DOI":"10.1093\/med\/9780198570295.003.0105"},{"key":"e_1_2_13_36_1","doi-asserted-by":"publisher","DOI":"10.1177\/1474515120926069"},{"key":"e_1_2_13_37_1","doi-asserted-by":"publisher","DOI":"10.4082\/kjfm.18.0079"},{"key":"e_1_2_13_38_1","doi-asserted-by":"publisher","DOI":"10.1111\/scs.12283"},{"key":"e_1_2_13_39_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpubh.2022.878259"},{"issue":"2","key":"e_1_2_13_40_1","first-page":"53","article-title":"Effects of Empowerment Program on the Burden of Care in Mothers of Children With Phenylketonuria","volume":"13","author":"Rahgoi A.","year":"2019","journal-title":"Iranian Journal of Child Neurology"},{"issue":"4","key":"e_1_2_13_41_1","first-page":"3","article-title":"Perceived Barriers to Primary Care Among Western Canadians With Chronic Conditions","volume":"25","author":"Ronksley P. E.","year":"2014","journal-title":"Health Reports"},{"key":"e_1_2_13_42_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12912\u2010023\u201001375\u2010w"},{"key":"e_1_2_13_43_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40520\u2010019\u201001370\u20109"},{"key":"e_1_2_13_44_1","doi-asserted-by":"publisher","DOI":"10.2147\/RMHP.S426598"},{"key":"e_1_2_13_45_1","doi-asserted-by":"publisher","DOI":"10.31557\/APJCP.2019.20.6.1757"},{"key":"e_1_2_13_46_1","doi-asserted-by":"publisher","DOI":"10.29252\/hnmj.28.3.198"},{"key":"e_1_2_13_47_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11255\u2010023\u201003482\u20108"},{"key":"e_1_2_13_48_1","doi-asserted-by":"publisher","DOI":"10.1111\/jocn.17091"},{"key":"e_1_2_13_49_1","unstructured":"Wang Z. L.2012.\u201cResearch on the Effect of Transitional Nursing Intervention on Family Caregivers of Stroke Patients.\u201dTianjin University [Dissertation]."},{"key":"e_1_2_13_50_1","doi-asserted-by":"publisher","DOI":"10.5888\/pcd11.130389"},{"key":"e_1_2_13_51_1","doi-asserted-by":"publisher","DOI":"10.31557\/APJCP.2022.23.3.1077"},{"key":"e_1_2_13_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gerinurse.2022.10.012"},{"key":"e_1_2_13_53_1","unstructured":"Xu J. M.2020.\u201cA Study of FCEM\u2010Based Discharge Planning in Patients With Prophylactic Enterostomies.\u201dNanHua University [Dissertation]."},{"key":"e_1_2_13_54_1","doi-asserted-by":"publisher","DOI":"10.4103\/nms.nms_45_18"},{"key":"e_1_2_13_55_1","doi-asserted-by":"publisher","DOI":"10.3969\/j.issn.1006\u20100588.2022.02.012"},{"key":"e_1_2_13_56_1","doi-asserted-by":"publisher","DOI":"10.3969\/j.issn.1009\u20100754.2023.05.007"},{"key":"e_1_2_13_57_1","unstructured":"Zhang Y.2021.\u201cA Study on the Effect of Family Empowerment Program on Caregivers' Ability to Care for Stroke Patients With Dysphagia.\u201dZhengzhou University [Dissertation]."},{"key":"e_1_2_13_58_1","doi-asserted-by":"publisher","DOI":"10.3870\/j.issn.1001\u20104152.2021.02.080"},{"key":"e_1_2_13_59_1","doi-asserted-by":"publisher","DOI":"10.1111\/ijn.13081"},{"key":"e_1_2_13_60_1","doi-asserted-by":"publisher","DOI":"10.3969\/j.issn.1671\u2010315x.2022.07.002"}],"container-title":["Journal of Clinical Nursing"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocn.70006","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jocn.70006","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocn.70006","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T03:23:02Z","timestamp":1788319382000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jocn.70006"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,1]]},"references-count":59,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,2]]}},"alternative-id":["10.1111\/jocn.70006"],"URL":"https:\/\/doi.org\/10.1111\/jocn.70006","archive":["Portico"],"relation":{},"ISSN":["0962-1067","1365-2702"],"issn-type":[{"value":"0962-1067","type":"print"},{"value":"1365-2702","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7,1]]},"assertion":[{"value":"2024-07-03","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-06-02","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-07-01","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}