{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T13:54:00Z","timestamp":1783000440837,"version":"3.54.5"},"reference-count":32,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T00:00:00Z","timestamp":1777507200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T00:00:00Z","timestamp":1777507200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100021529","name":"Prince of Wales Hospital Foundation","doi-asserted-by":"publisher","award":["2020\/NR8"],"award-info":[{"award-number":["2020\/NR8"]}],"id":[{"id":"10.13039\/501100021529","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Clinical Nursing"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To improve the rates of central line\u2013associated bloodstream infections in an intensive care and non\u2010intensive care setting in a large Australian health service.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Evidence\u2010based care bundles targeting central line practices were developed and implemented using a pragmatic action research\u2013approach.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Wards recruited change facilitators to implement the bundles. Compliance and ward engagement were measured, and pre\u2010intervention and intervention central line\u2013related infection rates were compared.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Wards showed a reduction in central line\u2013related infections by 90% during the intervention for up to 2\u2009years. Adherence to bundles was high in both settings. Improvements in insertion practices were observed after baseline and were sustained, with the largest improvement seen in documentation. Maintenance and removal practices showed less variation than insertion practices.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Care bundles are an effective intervention to reduce central\u2010line\u2010related infections over a sustained period when clinician adherence is high.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Implications for the Profession and\/or Patient Care<\/jats:title>\n                    <jats:p>Care bundles can be effective in high\u2010risk settings beyond intensive care units, including haemodialysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Impact<\/jats:title>\n                    <jats:p>Central lines were identified from local hospital data as a major contributor to health care\u2013associated infection rates. Care bundles were implemented in high\u2010risk settings and demonstrated sustained reductions in central\u2010line\u2010related infections. Care bundles are an effective intervention for health care organisations to reduce and sustain preventable infections in high\u2010risk patient cohorts.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Reporting Method<\/jats:title>\n                    <jats:p>We adhered to the Standards for Quality Improvement Reporting Excellence (SQUIRE 2.0) framework.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patient or Public Contribution<\/jats:title>\n                    <jats:p>No patient or public contribution.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jocn.70284","type":"journal-article","created":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T04:40:22Z","timestamp":1777610422000},"page":"3134-3145","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Using Evidence\u2010Based Care Bundles to Reduce Central Line\u2013Associated Infections in High\u2010Risk Settings"],"prefix":"10.1111","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8977-6363","authenticated-orcid":false,"given":"Karen","family":"Tuqiri","sequence":"first","affiliation":[{"name":"Nursing Executive Unit Prince of Wales Hospital, South Eastern Sydney Local Health District  Randwick Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Val","family":"Wilson","sequence":"additional","affiliation":[{"name":"Nursing Executive Unit Prince of Wales Hospital, South Eastern Sydney Local Health District  Randwick Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-6786-5329","authenticated-orcid":false,"given":"Nicole","family":"Pesa","sequence":"additional","affiliation":[{"name":"Nursing Executive Unit Prince of Wales Hospital, South Eastern Sydney Local Health District  Randwick Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,4,30]]},"reference":[{"key":"e_1_2_13_2_1","volume-title":"Central LineInsertion and Maintenance Guideline","author":"Australian and New Zealand Intensive Care Society (ANZICS)","year":"2012"},{"key":"e_1_2_13_3_1","unstructured":"Australian Commission on Safety and Quality in Health Care (ACSQHC).2018.\u201cHealthcare Associated Infections.\u201dhttps:\/\/www.safetyandquality.gov.au\/sites\/default\/files\/migrated\/Healthcare\u2010associated\u2010infection\u2010detailed\u2010fact\u2010sheet.pdf."},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471\u20102288\u201014\u201098"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajic.2020.11.0"},{"key":"e_1_2_13_6_1","volume-title":"Intravascular Access Devices (IVAD) \u2013 Infection Prevention & Control","author":"Clinical Excellence Commission","year":"2019"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13012\u2010017\u20100560\u20105"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2014.11.030"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cnc.2021.08.001"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.1017\/ice.2016.67"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13012\u2010019\u20100894\u20102"},{"key":"e_1_2_13_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/NAN.0000000000000396"},{"key":"e_1_2_13_13_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12913\u2010017\u20102070\u20101"},{"issue":"1","key":"e_1_2_13_14_1","first-page":"131","article-title":"Pragmatic Action Research","volume":"3","author":"Greenwood D. 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