{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T02:44:20Z","timestamp":1791945860612,"version":"4.3.4"},"reference-count":37,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2026,5,30]],"date-time":"2026-05-30T00:00:00Z","timestamp":1780099200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,5,30]],"date-time":"2026-05-30T00:00:00Z","timestamp":1780099200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100005669","name":"Funda\u00e7\u00e3o de Apoio \u00e0 Pesquisa do Estado da Para\u00edba","doi-asserted-by":"publisher","award":["47449.673.29754.11082021"],"award-info":[{"award-number":["47449.673.29754.11082021"]}],"id":[{"id":"10.13039\/501100005669","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Clinical Nursing"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>To evaluate the health\u2010related quality of life (HRQOL) of adults with Long COVID 2\u2009years and beyond after COVID\u201019 illness.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Cross\u2010sectional study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Health status was assessed using the EQ\u20105D\u20105L instrument among 226 adults diagnosed in primary care with mild\u2010to\u2010moderate COVID\u201019 during the 2021 pandemic. Data were collected through a cross\u2010sectional survey using a standardized questionnaire with a set of validated clinical outcomes for Long COVID. The sample consisted of adults aged \u2265\u200918\u2009years who attended the specified ambulatory settings, tested positive for SARS\u2010CoV\u20102, and agreed to be interviewed; the response rate was 70%. Health utility scores were compared between adults with and without Long COVID. Multivariate logistic regressions were applied to investigate the relationship between Long COVID and health\u2010related quality of life outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Data Sources<\/jats:title>\n                    <jats:p>Primary data were collected from six public Family Health Care Units in Jo\u00e3o Pessoa, Brazil, between May 2023 and July 2024.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Adults with Long COVID had statistically significantly lower median utility scores (0.784, IQR: 0.633\u20130.902) than those without persistent symptoms (1.0, IQR: 0.877\u20131.0). Poorer HRQOL was more evident among women, older adults, non\u2010White individuals, participants with pre\u2010existing chronic diseases, and those with lower educational attainment. Long COVID was associated with impairments in anxiety\/depression, pain\/discomfort and usual activities.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Adults with Long COVID experienced poorer HRQOL 2\u2009years or longer after mild\u2010to\u2010moderate infection compared with those without persistent symptoms, regardless of sex, age, ethnicity, education level or comorbidities. These findings support the implementation of targeted interventions and rehabilitation services in primary care for individuals experiencing long\u2010term health problems following COVID\u201019 illness.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Implications for the Profession and\/or Patient Care<\/jats:title>\n                    <jats:p>Identifying adults at greater risk of persistent health impairments following COVID\u201019 may help health professionals, caregivers and policymakers better address the aspects of patients' lives that lack quality and develop a multidisciplinary approach in primary care to managing this condition.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Impact<\/jats:title>\n                    <jats:p>\n                      <jats:list list-type=\"bullet\">\n                        <jats:list-item>\n                          <jats:p>\n                            What problem did the study address?\n                            <jats:list list-type=\"explicit-label\">\n                              <jats:list-item>\n                                <jats:p>This study examined the association between persistent symptoms 2\u2009years or longer after non\u2010severe COVID\u201019 illness and health\u2010related quality of life.<\/jats:p>\n                              <\/jats:list-item>\n                            <\/jats:list>\n                          <\/jats:p>\n                        <\/jats:list-item>\n                        <jats:list-item>\n                          <jats:p>\n                            What were the main findings?\n                            <jats:list list-type=\"explicit-label\">\n                              <jats:list-item>\n                                <jats:p>Long COVID was associated with poorer health\u2010related quality of life, particularly in the domains of anxiety\/depression, pain\/discomfort and usual activities.<\/jats:p>\n                              <\/jats:list-item>\n                            <\/jats:list>\n                          <\/jats:p>\n                        <\/jats:list-item>\n                        <jats:list-item>\n                          <jats:p>\n                            Where and on whom will the research have an impact?\n                            <jats:list list-type=\"explicit-label\">\n                              <jats:list-item>\n                                <jats:p>The findings highlight the need for multidisciplinary management of long\u2010term health problems among adult COVID\u201019 survivors in primary care.<\/jats:p>\n                              <\/jats:list-item>\n                            <\/jats:list>\n                          <\/jats:p>\n                        <\/jats:list-item>\n                      <\/jats:list>\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Reporting Methods<\/jats:title>\n                    <jats:p>The STROBE checklist was followed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patient or Public Contribution<\/jats:title>\n                    <jats:p>No patient or public contribution.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jocn.70383","type":"journal-article","created":{"date-parts":[[2026,5,31]],"date-time":"2026-05-31T03:44:42Z","timestamp":1780199082000},"page":"4365-4377","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Health\u2010Related Quality of Life of Adults With Long\n                    <scp>COVID<\/scp>\n                    : A Cross\u2010Sectional Study in Primary Care"],"prefix":"10.1111","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7371-3752","authenticated-orcid":false,"given":"Assel Muratovna Shigayeva","family":"Ferreira","sequence":"first","affiliation":[{"name":"Center of Exact and Natural Sciences Federal University of Paraiba  Joao Pessoa Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fl\u00e1via Em\u00edlia Leite de Lima","family":"Ferreira","sequence":"additional","affiliation":[{"name":"Center of Health Sciences Federal University of Paraiba  Joao Pessoa Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jo\u00e3o Agnaldo","family":"do Nascimento","sequence":"additional","affiliation":[{"name":"Center of Exact and Natural Sciences Federal University of Paraiba  Joao Pessoa Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andr\u00e9 Lu\u00eds Bonif\u00e1cio","family":"de Carvalho","sequence":"additional","affiliation":[{"name":"Center of Medical Sciences Federal University of Paraiba  Joao Pessoa Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caio C\u00e9sar Ferreira","family":"Alverga","sequence":"additional","affiliation":[{"name":"Center of Health Sciences Federal University of Paraiba  Joao Pessoa Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6246-9769","authenticated-orcid":false,"given":"Leandro","family":"Pernambuco","sequence":"additional","affiliation":[{"name":"Center of Health Sciences Federal University of Pernambuco  Recife Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,5,30]]},"reference":[{"key":"e_1_2_11_2_1","unstructured":"Alverga C. 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