{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T06:49:08Z","timestamp":1792133348040,"version":"4.4.0"},"reference-count":35,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T00:00:00Z","timestamp":1792022400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T00:00:00Z","timestamp":1792022400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Clinical Nursing"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Moderate\u2010to\u2010severe pain remains a clinically relevant concern after paediatric laparoscopic pyeloplasty and may interfere with early recovery. Identifying children at increased risk may support more timely and individualized perioperative pain management.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>To investigate factors associated with moderate\u2010to\u2010severe pain after laparoscopic pyeloplasty in children and to inform targeted nursing and perioperative management strategies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This single\u2010centre retrospective observational study included children undergoing laparoscopic pyeloplasty. Postoperative pain was assessed at 2, 6, 12 and 24\u2009h using either a Faces Pain Scale or the Face, Legs, Activity, Cry and Consolability (FLACC) scale according to age and communication ability. Moderate\u2010to\u2010severe pain was defined as a score \u2265\u20094 at any assessment within 24\u2009h. Demographic, disease\u2010related, surgical and perioperative variables were analysed. Multivariable binary logistic regression was used to identify factors independently associated with moderate\u2010to\u2010severe pain, and repeated\u2010measures analysis of variance was used to assess changes in pain scores over time. This study was reported in accordance with the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) guidelines.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among 258 children, 65 developed moderate\u2010to\u2010severe postoperative pain, corresponding to an incidence of 25.2%. Multivariable analysis showed that age &lt;\u20093\u2009years, significant preoperative anxiety, operative time\u2009\u2265\u2009120\u2009min and the absence of a regional block were independently associated with moderate\u2010to\u2010severe pain. Sex, severe hydronephrosis and postoperative drainage tube placement were not independently associated with the outcome. Pain scores were highest at approximately 6\u2009h after surgery, with significant group, time and group\u2010by\u2010time interaction effects.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Moderate\u2010to\u2010severe pain is relatively common during the early postoperative period after paediatric laparoscopic pyeloplasty. Early risk identification, preoperative psychological support, appropriate regional analgesia and intensified pain assessment during the first 6\u201312\u2009h may improve perioperative pain management. Prospective multicentre studies are warranted to validate these findings and develop clinically applicable risk\u2010stratification strategies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jocn.70583","type":"journal-article","created":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T06:29:32Z","timestamp":1792132172000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Factors Associated With Moderate\u2010to\u2010Severe Pain After Paediatric Laparoscopic Pyeloplasty: Implications for Nursing Care"],"prefix":"10.1111","author":[{"given":"Yueqin","family":"Xiang","sequence":"first","affiliation":[{"name":"Department of Nursing Children's Hospital of Nanjing Medical University  Nanjing Jiangsu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruxia","family":"Min","sequence":"additional","affiliation":[{"name":"Department of Nursing Children's Hospital of Nanjing Medical University  Nanjing Jiangsu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lianlian","family":"Ge","sequence":"additional","affiliation":[{"name":"Department of Nursing Children's Hospital of Nanjing Medical University  Nanjing Jiangsu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-3333-7053","authenticated-orcid":false,"given":"Lanzheng","family":"Bian","sequence":"additional","affiliation":[{"name":"Department of Nursing Children's Hospital of Nanjing Medical University  Nanjing Jiangsu China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,15]]},"reference":[{"issue":"5","key":"e_1_2_13_2_1","doi-asserted-by":"crossref","first-page":"549","DOI":"10.5005\/jp-journals-10005-3463","article-title":"Comparative Evaluation of Pain Perception and Postoperative Pain in Children With Precooled Injection Sites Using Popsicles for Local Anesthesia: A Randomized Controlled Trial","volume":"19","author":"Baldawa H. S.","year":"2026","journal-title":"International Journal of Clinical Pediatric Dentistry"},{"key":"e_1_2_13_3_1","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejon.2025.103065","article-title":"Efficacy of Topical Anesthetic Cream, Cold Angiocath, and Their Combination on Pain and Fear During Pediatric Oncology Venipuncture: A Double\u2010Blind Randomized Controlled Trial","volume":"80","author":"Borzoee F.","year":"2026","journal-title":"European Journal of Oncology Nursing"},{"issue":"4","key":"e_1_2_13_4_1","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1111\/anae.70092","article-title":"Patient\u2010Reported Outcomes, Postoperative Pain and Pain Relief After Day\u2010Case Surgery (POPPY): Chronic Post\u2010Surgical Pain Prevalence and Associations","volume":"81","author":"Brayne A. B.","year":"2026","journal-title":"Anaesthesia"},{"issue":"3","key":"e_1_2_13_5_1","doi-asserted-by":"crossref","first-page":"183","DOI":"10.36076\/ppj.2025.28.183","article-title":"A Systematic Review of Self\u2010Reported Pain Rating Scales for Children and Adolescents","volume":"28","author":"Calvano J.","year":"2025","journal-title":"Pain Physician"},{"issue":"8","key":"e_1_2_13_6_1","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1089\/lap.2025.0007","article-title":"Comparative Outcomes of Laparoscopic, Retroperitoneoscopic, and One\u2010Trocar\u2010Assisted\u2010Pyeloplasty in Pediatric Ureteropelvic Junction Obstruction: A Scoping Review of Literature","volume":"35","author":"Cassaro F.","year":"2025","journal-title":"Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A"},{"key":"e_1_2_13_7_1","doi-asserted-by":"crossref","first-page":"e244","DOI":"10.1016\/j.pedn.2024.07.012","article-title":"The Effects of Preoperative Therapeutic Play on Anxiety and Fear Levels in Preschool Children","volume":"78","author":"Celik B.","year":"2024","journal-title":"Journal of Pediatric Nursing"},{"issue":"4","key":"e_1_2_13_8_1","doi-asserted-by":"crossref","first-page":"1493","DOI":"10.1111\/jocn.17582","article-title":"Non\u2010Pharmacological Interventions for Preoperative Anxiety in Children: A Systematic Review and Network Meta\u2010Analysis","volume":"34","author":"Chen H.","year":"2025","journal-title":"Journal of Clinical Nursing"},{"issue":"10","key":"e_1_2_13_9_1","first-page":"723","article-title":"Risk and Protective Factors in Predicting Pediatric Acute Postsurgical Pain: A Systematic Review and Meta\u2010Analysis","volume":"42","author":"Chow C. H. T.","year":"2023","journal-title":"Health Psychology"},{"issue":"10","key":"e_1_2_13_10_1","doi-asserted-by":"crossref","first-page":"3107","DOI":"10.1007\/s11255-025-04495-1","article-title":"Long\u2010Term Renal Function Post\u2010Pyeloplasty: A Systematic Review","volume":"57","author":"Christanto R. B. I.","year":"2025","journal-title":"International Urology and Nephrology"},{"issue":"2","key":"e_1_2_13_11_1","doi-asserted-by":"crossref","first-page":"231","DOI":"10.21037\/tp-2024-503","article-title":"Comparative Analysis of Laparoscopic and Transumbilical Incision Open Pyeloplasty for Treatment of Infants With Ureteropelvic Junction Obstruction: A Clinical Efficacy and Safety Study","volume":"14","author":"Chu H.","year":"2025","journal-title":"Translational Pediatrics"},{"issue":"5","key":"e_1_2_13_12_1","article-title":"Postoperative Pain Outcomes and Satisfaction in Preschool Versus School\u2010Age Children: A Prospective Multicenter Observational Study","volume":"18","author":"El\u2010Tallawy S. N.","year":"2026","journal-title":"Cureus"},{"issue":"3","key":"e_1_2_13_13_1","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1016\/j.jopan.2023.08.021","article-title":"The Effect of Child Preference for Parental Selection on Pediatric Anxiety During Induction in Children Undergoing Elective Day Case Surgery","volume":"39","author":"Fatih Y.","year":"2024","journal-title":"Journal of Perianesthesia Nursing"},{"issue":"7","key":"e_1_2_13_14_1","doi-asserted-by":"crossref","first-page":"1297","DOI":"10.1016\/j.jpedsurg.2024.03.027","article-title":"Updates From the Other Side of the Drape: Recent Advances in Multimodal Pain Management and Opioid Reduction Among Pediatric Surgical Patients","volume":"59","author":"Franklin A. D.","year":"2024","journal-title":"Journal of Pediatric Surgery"},{"key":"e_1_2_13_15_1","doi-asserted-by":"crossref","first-page":"1236","DOI":"10.1016\/j.jopan.2026.04.011","article-title":"The Effect of Preoperative Child and Parental Anxiety on Emergence Agitation and Postoperative Pain in Children Undergoing Adenoidectomy and Tonsillectomy: A Prospective Observational Study","volume":"41","author":"Gemici D.","year":"2026","journal-title":"Journal of Perianesthesia Nursing"},{"issue":"1","key":"e_1_2_13_16_1","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1097\/ALN.0000000000005790","article-title":"2026 American Society of Anesthesiologists Practice Guideline on Perioperative Pain Management Using Local and Regional Analgesia for Cardiothoracic Surgeries, Mastectomy, and Abdominal Surgeries","volume":"144","author":"Joshi G. P.","year":"2026","journal-title":"Anesthesiology"},{"issue":"9","key":"e_1_2_13_17_1","doi-asserted-by":"crossref","first-page":"1705","DOI":"10.1111\/jocn.16156","article-title":"Effectiveness of Interventions Used to Prepare Preschool Children and Their Parents for Day Surgery: A Systematic Review and Meta\u2010Analysis of Randomised Controlled Trials","volume":"32","author":"Kerimaa H.","year":"2023","journal-title":"Journal of Clinical Nursing"},{"issue":"3","key":"e_1_2_13_18_1","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1089\/end.2016.0846","article-title":"A Non\u2010Narcotic Pathway for the Management of Postoperative Pain Following Pediatric Robotic Pyeloplasty","volume":"31","author":"Lee Z.","year":"2017","journal-title":"Journal of Endourology"},{"issue":"2","key":"e_1_2_13_19_1","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/j.pcl.2025.11.007","article-title":"Multimodal Perioperative Pain Management for Children With Medical Complexity","volume":"73","author":"Mann K.","year":"2026","journal-title":"Pediatric Clinics of North America"},{"issue":"3","key":"e_1_2_13_20_1","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1055\/a-2708-2796","article-title":"Intercostal Nerve Cryoablation for Postoperative Pain Control After the Nuss Procedure in Children: A Systematic Review and Meta\u2010Analysis","volume":"36","author":"Marques D.","year":"2026","journal-title":"European Journal of Pediatric Surgery"},{"issue":"4","key":"e_1_2_13_21_1","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1016\/j.jopan.2021.10.002","article-title":"Anxiety and Pain in Children Undergoing Surgery: A Scoping Review","volume":"37","author":"Mathias E. G.","year":"2022","journal-title":"Journal of Perianesthesia Nursing"},{"issue":"3","key":"e_1_2_13_22_1","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1177\/13674935211062336","article-title":"Non\u2010Pharmacological Interventions to Reduce Anxiety Among Children Undergoing Surgery: A Systematic Review","volume":"27","author":"Mathias E. G.","year":"2023","journal-title":"Journal of Child Health Care"},{"issue":"8","key":"e_1_2_13_23_1","doi-asserted-by":"crossref","DOI":"10.1016\/j.jpedsurg.2026.163233","article-title":"Postoperative Pain After Low\u2010Pressure Versus Standard\u2010Pressure Laparoscopic Surgery in Children. A Randomized Clinical Trial","volume":"61","author":"Neeser H. R.","year":"2026","journal-title":"Journal of Pediatric Surgery"},{"key":"e_1_2_13_24_1","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.2147\/JPR.S397064","article-title":"A Systematic Review of the Measurement Properties of Face, Legs, Activity, Cry and Consolability Scale for Pediatric Pain Assessment","volume":"16","author":"Peng T.","year":"2023","journal-title":"Journal of Pain Research"},{"issue":"5","key":"e_1_2_13_25_1","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1002\/ejp.1936","article-title":"Detection and Assessment of Postoperative Pain in Children With Cognitive Impairment: A Systematic Literature Review and Meta\u2010Analysis","volume":"26","author":"Pizzinato A.","year":"2022","journal-title":"European Journal of Pain"},{"issue":"1","key":"e_1_2_13_26_1","doi-asserted-by":"crossref","first-page":"127","DOI":"10.4103\/joacp.joacp_173_22","article-title":"Comparison of Analgesic Efficacy of Ultrasound\u2010Guided Quadratus Lumborum Block Versus Erector Spinae Plane Block in Children Undergoing Elective Open Pyeloplasty\u2014A Randomized, Double\u2010Blinded, Controlled Study","volume":"40","author":"Ralte I. L.","year":"2024","journal-title":"Journal of Anaesthesiology Clinical Pharmacology"},{"issue":"3","key":"e_1_2_13_27_1","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.1097\/MS9.0000000000001742","article-title":"Severity and Associated Factors of Postoperative Pain in Paediatric Surgical Patients Aged 2 Months\u20107\u2009Years at Selected Addis Ababa Public Hospitals: A Multicenter Prospective Longitudinal Study","volume":"86","author":"Rede F. M.","year":"2024","journal-title":"Annals of Medicine and Surgery"},{"key":"e_1_2_13_28_1","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/j.pedn.2025.11.032","article-title":"The Effect of the Magic Glove Technique on Pain and Anxiety in Children During Leuprolide Injection: A Quasi\u2010Experimental Study","volume":"86","author":"Sadat Hosseini A. S.","year":"2026","journal-title":"Journal of Pediatric Nursing"},{"issue":"2","key":"e_1_2_13_29_1","article-title":"Comparison of Bupivacaine Trocar Site Infiltration and Peritoneal Instillation for Postoperative Pain in Pediatric Laparoscopic Surgery","volume":"17","author":"Saleem M. M.","year":"2025","journal-title":"Cureus"},{"issue":"3","key":"e_1_2_13_30_1","doi-asserted-by":"crossref","first-page":"221","DOI":"10.23736\/S0375-9393.26.19427-9","article-title":"Optimizing Postoperative Pain Management in Children: Evidence, Pitfalls, and Practical Recommendations","volume":"92","author":"Simonte R.","year":"2026","journal-title":"Minerva Anestesiologica"},{"issue":"1","key":"e_1_2_13_31_1","doi-asserted-by":"crossref","first-page":"10","DOI":"10.4081\/pmc.2023.288","article-title":"Correlation Between FLACC Scale Score and Analgesic Requirement in Children Undergoing Minimally Invasive Surgery","volume":"45","author":"Turco A.","year":"2023","journal-title":"La Pediatria Medica e Chirurgica"},{"issue":"6","key":"e_1_2_13_32_1","doi-asserted-by":"crossref","DOI":"10.1016\/j.accpm.2024.101427","article-title":"Postoperative Pain Management in Children: Guidance From the Pain Committee of the European Society for Paediatric Anaesthesiology (ESPA Pain Management Ladder Initiative) Part II","volume":"43","author":"Vittinghoff M.","year":"2024","journal-title":"Anaesthesia Critical Care & Pain Medicine"},{"key":"e_1_2_13_33_1","doi-asserted-by":"crossref","DOI":"10.1177\/30502225261442771","article-title":"Postoperative Pain in Children: A Real Emergency","volume":"13","author":"Vittori A.","year":"2026","journal-title":"SAGE Open Pediatrics"},{"key":"e_1_2_13_34_1","first-page":"1","article-title":"Validation of the Emoji Faces Pain Scale for Evaluating Acute Procedural Pain in Children Aged 3\u20105\u2009Years","volume":"21","author":"Wan X.","year":"2026","journal-title":"Pain Management Nursing"},{"issue":"2","key":"e_1_2_13_35_1","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1097\/AJP.0000000000001172","article-title":"Perioperative Regional Anesthesia Pain Outcomes in Children: A Retrospective Study of 3160 Regional Anesthetics in Routine Practice","volume":"40","author":"Xie J.","year":"2024","journal-title":"Clinical Journal of Pain"},{"issue":"1","key":"e_1_2_13_36_1","doi-asserted-by":"crossref","DOI":"10.1111\/ped.70433","article-title":"Pain Assessment Tools for Infants, Children, and Adolescents With Cancer: A Scoping Review","volume":"68","author":"Yamaji N.","year":"2026","journal-title":"Pediatrics International"}],"container-title":["Journal of Clinical Nursing"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocn.70583","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jocn.70583","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocn.70583","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T06:29:36Z","timestamp":1792132176000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jocn.70583"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10,15]]},"references-count":35,"alternative-id":["10.1111\/jocn.70583"],"URL":"https:\/\/doi.org\/10.1111\/jocn.70583","archive":["Portico"],"relation":{},"ISSN":["0962-1067","1365-2702"],"issn-type":[{"value":"0962-1067","type":"print"},{"value":"1365-2702","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10,15]]},"assertion":[{"value":"2026-08-10","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-15","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-10-15","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"jocn.70583"}}