{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T06:48:34Z","timestamp":1745390914903},"reference-count":51,"publisher":"Hindawi Limited","issue":"3","license":[{"start":{"date-parts":[[2016,1,19]],"date-time":"2016-01-19T00:00:00Z","timestamp":1453161600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"},{"start":{"date-parts":[[2016,1,19]],"date-time":"2016-01-19T00:00:00Z","timestamp":1453161600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Card Surg"],"published-print":{"date-parts":[[2016,3]]},"DOI":"10.1111\/jocs.12693","type":"journal-article","created":{"date-parts":[[2016,1,20]],"date-time":"2016-01-20T04:48:40Z","timestamp":1453265320000},"page":"156-160","source":"Crossref","is-referenced-by-count":4,"title":["Cryptogenic Stroke with a Patent Foramen Ovale:"],"prefix":"10.1155","volume":"31","author":[{"given":"Kareem","family":"Bedeir","sequence":"first","affiliation":[{"name":"Brigham and Women's Hospital; Boston Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Volpi","sequence":"additional","affiliation":[{"name":"Methodist DeBakey Heart and Vascular Center; Houston Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Basel","family":"Ramlawi","sequence":"additional","affiliation":[{"name":"Methodist DeBakey Heart and Vascular Center; Houston Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"98","published-online":{"date-parts":[[2016,1,19]]},"reference":[{"key":"10.1111\/jocs.12693-BIB0001|jocs12693-cit-0001","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1002\/ana.410250410","article-title":"Infarcts of undetermined cause: The NINCDS stroke data bank","volume":"25","author":"Sacco","year":"1989","journal-title":"Ann Neurol"},{"key":"10.1111\/jocs.12693-BIB0002|jocs12693-cit-0002","doi-asserted-by":"crossref","unstructured":"Cohnheim J 1877 1 134","DOI":"10.1136\/bmj.1.840.134"},{"key":"10.1111\/jocs.12693-BIB0003|jocs12693-cit-0003","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1161\/CIRCULATIONAHA.104.524371","article-title":"Patent foramen ovale and stroke","volume":"112","author":"Homma","year":"2005","journal-title":"Circulation"},{"key":"10.1111\/jocs.12693-BIB0004|jocs12693-cit-0004","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/S0025-6196(12)60336-X","article-title":"Incidence and size of patent foramen ovale during the first 10 decades of life: An autopsy study of 965 normal hearts","volume":"59","author":"Hagen","year":"1984","journal-title":"Mayo Clin Proc"},{"key":"10.1111\/jocs.12693-BIB0005|jocs12693-cit-0005","doi-asserted-by":"crossref","first-page":"862","DOI":"10.4065\/74.9.862","article-title":"Prevalence of potential risk factors for stroke assessed by transesophageal echocardiography and carotid ultrasonography: The SPARC study. Stroke Prevention: Assessment of Risk in a Community","volume":"74","author":"Meissner","year":"1999","journal-title":"Mayo Clin Proc"},{"key":"10.1111\/jocs.12693-BIB0006|jocs12693-cit-0006","doi-asserted-by":"crossref","first-page":"2407","DOI":"10.1161\/01.STR.31.10.2407","article-title":"Morphological and functional characteristics of patent foramen ovale and their embolic implications","volume":"31","author":"De Castro","year":"2000","journal-title":"Stroke"},{"key":"10.1111\/jocs.12693-BIB0007|jocs12693-cit-0007","doi-asserted-by":"crossref","first-page":"1865","DOI":"10.1161\/01.STR.24.12.1865","article-title":"Atrial septal aneurysm and patent foramen ovale as risk factors for cryptogenic stroke in patients less than 55 years of age. A study using transesophageal echocardiography","volume":"24","author":"Cabanes","year":"1993","journal-title":"Stroke"},{"key":"10.1111\/jocs.12693-BIB0008|jocs12693-cit-0008","doi-asserted-by":"crossref","first-page":"461","DOI":"10.7326\/0003-4819-117-6-461","article-title":"Patent foramen ovale as a risk factor for cryptogenic stroke","volume":"117","author":"Di Tullio","year":"1992","journal-title":"Ann Intern Med"},{"key":"10.1111\/jocs.12693-BIB0009|jocs12693-cit-0009","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1016\/0002-9149(92)90210-P","article-title":"Diagnosis of patent foramen ovale by transesophageal echocardiography and association with cerebral and peripheral embolic events","volume":"70","author":"Hausmann","year":"1992","journal-title":"Am J Cardiol"},{"key":"10.1111\/jocs.12693-BIB0010|jocs12693-cit-0010","doi-asserted-by":"crossref","first-page":"1148","DOI":"10.1056\/NEJM198805053181802","article-title":"Prevalence of patent foramen ovale in patients with stroke","volume":"318","author":"Lechat","year":"1988","journal-title":"N Engl J Med"},{"key":"10.1111\/jocs.12693-BIB0011|jocs12693-cit-0011","doi-asserted-by":"crossref","first-page":"2262","DOI":"10.1056\/NEJMoa071422","article-title":"Patent foramen ovale and cryptogenic stroke in older patients","volume":"357","author":"Handke","year":"2007","journal-title":"N Engl J Med"},{"key":"10.1111\/jocs.12693-BIB0012|jocs12693-cit-0012","doi-asserted-by":"crossref","first-page":"1172","DOI":"10.1212\/WNL.55.8.1172","article-title":"Interatrial septal abnormalities and stroke: A meta-analysis of case-control studies","volume":"55","author":"Overell","year":"2000","journal-title":"Neurology"},{"key":"10.1111\/jocs.12693-BIB0013|jocs12693-cit-0013","doi-asserted-by":"crossref","first-page":"2625","DOI":"10.1161\/01.CIR.0000017498.88393.44","article-title":"Effect of medical treatment in stroke patients with patent foramen ovale: Patent foramen ovale in cryptogenic stroke study","volume":"105","author":"Homma","year":"2002","journal-title":"Circulation"},{"key":"10.1111\/jocs.12693-BIB0014|jocs12693-cit-0014","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1212\/WNL.0b013e3181aa2a19","article-title":"Recurrent cerebral ischemia in medically treated patent foramen ovale: A meta-analysis","volume":"73","author":"Almekhlafi","year":"2009","journal-title":"Neurology"},{"key":"10.1111\/jocs.12693-BIB0015|jocs12693-cit-0015","doi-asserted-by":"crossref","first-page":"S26","DOI":"10.1161\/STROKEAHA.110.595140","article-title":"Is patent foramen ovale a modifiable risk factor for stroke recurrence","volume":"41","author":"Kent","year":"2010","journal-title":"Stroke"},{"key":"10.1111\/jocs.12693-BIB0016|jocs12693-cit-0016","doi-asserted-by":"crossref","first-page":"1002","DOI":"10.1016\/S0735-1097(85)80449-6","article-title":"Impending paradoxical embolism from atrial thrombus: Correct diagnosis by transesophageal echocardiography and prevention by surgery","volume":"5","author":"Nellessen","year":"1985","journal-title":"J Am Coll Cardiol"},{"key":"10.1111\/jocs.12693-BIB0017|jocs12693-cit-0017","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1016\/S1010-7940(98)00251-6","article-title":"Diagnosis and management of entrapped embolus through a patent foramen ovale","volume":"14","author":"Aboyans","year":"1998","journal-title":"Eur J Cardiothorac Surg"},{"key":"10.1111\/jocs.12693-BIB0018|jocs12693-cit-0018","first-page":"1426","article-title":"Impending paradoxical embolus: A case report and review of the literature","volume":"19","author":"Chow","year":"2003","journal-title":"Can J Cardiol"},{"key":"10.1111\/jocs.12693-BIB0019|jocs12693-cit-0019","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1016\/j.acvd.2008.08.011","article-title":"Surgical or medical treatment for thrombus straddling the patent foramen ovale: Impending paradoxical embolism? Report of four clinical cases and literature review","volume":"101","author":"Fauveau","year":"2008","journal-title":"Arch Cardiovasc Dis"},{"key":"10.1111\/jocs.12693-BIB0020|jocs12693-cit-0020","doi-asserted-by":"crossref","first-page":"e173","DOI":"10.1016\/j.jstrokecerebrovasdis.2015.03.027","article-title":"Thrombus in transit with isolated paradoxical embolism to the subclavian artery","volume":"24","author":"Bedeir","year":"2015","journal-title":"J Stroke Cerebrovasc Dis"},{"key":"10.1111\/jocs.12693-BIB0021|jocs12693-cit-0021","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1007\/s00595-006-3195-8","article-title":"Massive pulmonary embolism complicated by a patent foramen ovale with straddling thrombus: Report of a case","volume":"36","author":"Erkut","year":"2006","journal-title":"Surg Today"},{"key":"10.1111\/jocs.12693-BIB0022|jocs12693-cit-0022","doi-asserted-by":"crossref","first-page":"2245","DOI":"10.1016\/S0735-1097(03)00479-0","article-title":"Right heart thrombi in pulmonary embolism: Results from the international cooperative pulmonary embolism registry","volume":"41","author":"Torbicki","year":"2003","journal-title":"J Am Coll Cardiol"},{"key":"10.1111\/jocs.12693-BIB0023|jocs12693-cit-0023","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1097\/HCO.0b013e32831311bd","article-title":"Cryptogenic stroke and patent foramen ovale","volume":"23","author":"Thaler","year":"2008","journal-title":"Curr Opin Cardiol"},{"key":"10.1111\/jocs.12693-BIB0024|jocs12693-cit-0024","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1212\/WNL.0b013e3182a08d59","article-title":"An index to identify stroke-related vs incidental patent foramen ovale in cryptogenic stroke","volume":"81","author":"Kent","year":"2013","journal-title":"Neurology"},{"key":"10.1111\/jocs.12693-BIB0025|jocs12693-cit-0025","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1212\/WNL.0000000000000589","article-title":"Recurrent stroke predictors differ in medically treated patients with pathogenic vs. other PFOs","volume":"83","author":"Thaler","year":"2014","journal-title":"Neurology"},{"key":"10.1111\/jocs.12693-BIB0026|jocs12693-cit-0026","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1016\/0002-8703(89)90274-3","article-title":"Efficacy of treatment of patients with echocardiographically detected right-sided heart thrombi: A meta-analysis","volume":"118","author":"Kinney","year":"1989","journal-title":"Am Heart J"},{"key":"10.1111\/jocs.12693-BIB0027|jocs12693-cit-0027","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1001\/archinte.158.5.438","article-title":"Impending paradoxical embolism","volume":"158","author":"Meacham","year":"1998","journal-title":"Arch Intern Med"},{"issue":"1074","key":"10.1111\/jocs.12693-BIB0028|jocs12693-cit-0028","first-page":"e1071","article-title":"Transit thrombus entrapped in patent foramen ovale resolved without clinical embolic events","volume":"19","author":"Can","year":"2006","journal-title":"J Am Soc Echocardiogr"},{"key":"10.1111\/jocs.12693-BIB0029|jocs12693-cit-0029","doi-asserted-by":"crossref","first-page":"1284","DOI":"10.1093\/oxfordjournals.eurheartj.a060667","article-title":"Impending paradoxical embolism: A case report and literature review","volume":"15","author":"Hargreaves","year":"1994","journal-title":"Eur Heart J"},{"key":"10.1111\/jocs.12693-BIB0030|jocs12693-cit-0030","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1016\/S0002-9149(99)80118-0","article-title":"Spontaneous closure of a patent foramen ovale and disappearance of impending paradoxical embolism after fibrinolytic therapy in the course of massive pulmonary embolism","volume":"76","author":"Zerio","year":"1995","journal-title":"Am J Cardiol"},{"key":"10.1111\/jocs.12693-BIB0031|jocs12693-cit-0031","doi-asserted-by":"crossref","first-page":"2779","DOI":"10.1161\/01.CIR.99.21.2779","article-title":"Free-floating thrombi in the right heart: Diagnosis, management, and prognostic indexes in 38 consecutive patients","volume":"99","author":"Chartier","year":"1999","journal-title":"Circulation"},{"key":"10.1111\/jocs.12693-BIB0032|jocs12693-cit-0032","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1378\/chest.07-2656","article-title":"Combined clot fragmentation and aspiration in patients with acute pulmonary embolism","volume":"134","author":"Eid-Lidt","year":"2008","journal-title":"Chest"},{"key":"10.1111\/jocs.12693-BIB0033|jocs12693-cit-0033","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1016\/j.athoracsur.2014.04.060","article-title":"Utilization of angiovac and snare for eradication of a mobile right atrial thrombus","volume":"99","author":"Grimm","year":"2015","journal-title":"Ann Thorac Surg"},{"key":"10.1111\/jocs.12693-BIB0034|jocs12693-cit-0034","doi-asserted-by":"crossref","DOI":"10.1002\/ccd.24972","article-title":"A novel technique to remove a right atrial thrombotic mass attached to a patent foramen ovale (PFO) closure device","author":"Wunderlich","year":"2013","journal-title":"Catheter Cardiovasc Interv"},{"key":"10.1111\/jocs.12693-BIB0035|jocs12693-cit-0035","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/S0735-1097(00)00734-8","article-title":"Massive pulmonary embolism: Percutaneous emergency treatment by pigtail rotation catheter","volume":"36","author":"Schmitz-Rode","year":"2000","journal-title":"J Am Coll Cardiol"},{"key":"10.1111\/jocs.12693-BIB0036|jocs12693-cit-0036","doi-asserted-by":"crossref","first-page":"2139","DOI":"10.1161\/CIRCULATIONAHA.111.023689","article-title":"Catheter-based reperfusion treatment of pulmonary embolism","volume":"124","author":"Engelberger","year":"2011","journal-title":"Circulation"},{"key":"10.1111\/jocs.12693-BIB0037|jocs12693-cit-0037","doi-asserted-by":"crossref","first-page":"1740","DOI":"10.1056\/NEJMoa011503","article-title":"Recurrent cerebrovascular events associated with patent foramen ovale, atrial septal aneurysm, or both","volume":"345","author":"Mas","year":"2001","journal-title":"N Engl J Med"},{"key":"10.1111\/jocs.12693-BIB0038|jocs12693-cit-0038","doi-asserted-by":"crossref","first-page":"2381","DOI":"10.1093\/eurheartj\/ehv252","article-title":"Anticoagulant vs. Antiplatelet therapy in patients with cryptogenic stroke and patent foramen ovale: An individual participant data meta-analysis","volume":"36","author":"Kent","year":"2015","journal-title":"Eur Heart J"},{"key":"10.1111\/jocs.12693-BIB0039|jocs12693-cit-0039","doi-asserted-by":"crossref","first-page":"2160","DOI":"10.1161\/STR.0000000000000024","article-title":"Guidelines for the prevention of stroke in patients with stroke and transient ischemic attack: A guideline for healthcare professionals from the American Heart Association\/American Stroke Association","volume":"45","author":"Kernan","year":"2014","journal-title":"Stroke"},{"key":"10.1111\/jocs.12693-BIB0040|jocs12693-cit-0040","doi-asserted-by":"crossref","first-page":"e601S","DOI":"10.1378\/chest.11-2302","article-title":"Antithrombotic and thrombolytic therapy for ischemic stroke: Antithrombotic therapy and prevention of thrombosis, 9th ed: American College of Chest Physicians evidence-based clinical practice guidelines","volume":"141","author":"Lansberg","year":"2012","journal-title":"Chest"},{"key":"10.1111\/jocs.12693-BIB0041|jocs12693-cit-0041","doi-asserted-by":"crossref","first-page":"753","DOI":"10.7326\/0003-4819-139-9-200311040-00010","article-title":"Transcatheter closure versus medical therapy of patent foramen ovale and presumed paradoxical thromboemboli: A systematic review","volume":"139","author":"Khairy","year":"2003","journal-title":"Ann Intern Med"},{"key":"10.1111\/jocs.12693-BIB0042|jocs12693-cit-0042","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1056\/NEJMoa1009639","article-title":"Closure or medical therapy for cryptogenic stroke with patent foramen ovale","volume":"366","author":"Furlan","year":"2012","journal-title":"N Engl J Med"},{"key":"10.1111\/jocs.12693-BIB0043|jocs12693-cit-0043","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1056\/NEJMoa1211716","article-title":"Percutaneous closure of patent foramen ovale in cryptogenic embolism","volume":"368","author":"Meier","year":"2013","journal-title":"N Engl J Med"},{"key":"10.1111\/jocs.12693-BIB0044|jocs12693-cit-0044","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.1056\/NEJMoa1301440","article-title":"Closure of patent foramen ovale versus medical therapy after cryptogenic stroke","volume":"368","author":"Carroll","year":"2013","journal-title":"N Engl J Med"},{"key":"10.1111\/jocs.12693-BIB0045|jocs12693-cit-0045","doi-asserted-by":"crossref","first-page":"f6193","DOI":"10.1136\/bmj.f6193","article-title":"Is closure of patent foramen ovale to prevent ischaemic stroke ever justified","volume":"347","author":"Henderson","year":"2013","journal-title":"BMJ"},{"key":"10.1111\/jocs.12693-BIB0046|jocs12693-cit-0046","doi-asserted-by":"crossref","first-page":"3342","DOI":"10.1093\/eurheartj\/eht285","article-title":"Patent foramen ovale transcatheter closure vs. medical therapy on recurrent vascular events: A systematic review and meta-analysis of randomized controlled trials","volume":"34","author":"Rengifo-Moreno","year":"2013","journal-title":"Eur Heart J"},{"key":"10.1111\/jocs.12693-BIB0047|jocs12693-cit-0047","doi-asserted-by":"crossref","first-page":"2640","DOI":"10.1161\/STROKEAHA.113.001773","article-title":"Potentially large yet uncertain benefits: A meta-analysis of patent foramen ovale closure trials","volume":"44","author":"Kitsios","year":"2013","journal-title":"Stroke"},{"key":"10.1111\/jocs.12693-BIB0048|jocs12693-cit-0048","doi-asserted-by":"crossref","first-page":"4132","DOI":"10.1016\/j.ijcard.2013.07.077","article-title":"Percutaneous closure of patent foramen ovale for cryptogenic stroke: A meta-analysis of randomized controlled trials","volume":"168","author":"Kwong","year":"2013","journal-title":"Int J Cardiol"},{"key":"10.1111\/jocs.12693-BIB0049|jocs12693-cit-0049","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1016\/j.carrev.2013.08.010","article-title":"Safety and efficacy of device closure for patent foramen ovale for secondary prevention of neurological events: Comprehensive systematic review and meta-analysis of randomized controlled trials","volume":"14","author":"Hakeem","year":"2013","journal-title":"Cardiovasc Revasc Med"},{"key":"10.1111\/jocs.12693-BIB0050|jocs12693-cit-0050","doi-asserted-by":"crossref","first-page":"e004282","DOI":"10.1136\/bmjopen-2013-004282","article-title":"Systematic review of percutaneous closure versus medical therapy in patients with cryptogenic stroke and patent foramen ovale","volume":"4","author":"Spencer","year":"2014","journal-title":"BMJ Open"},{"key":"10.1111\/jocs.12693-BIB0051|jocs12693-cit-0051","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1001\/jama.2009.1012","article-title":"Prevalence and repair of intraoperatively diagnosed patent foramen ovale and association with perioperative outcomes and long-term survival","volume":"302","author":"Krasuski","year":"2009","journal-title":"JAMA"}],"container-title":["Journal of Cardiac Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjocs.12693","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjocs.12693","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.1111\/jocs.12693\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,1,6]],"date-time":"2023-01-06T11:48:26Z","timestamp":1673005706000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jocs.12693"}},"subtitle":["Medical Therapy, Percutaneous Intervention, or Surgery"],"short-title":[],"issued":{"date-parts":[[2016,1,19]]},"references-count":51,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2016,3]]}},"URL":"https:\/\/doi.org\/10.1111\/jocs.12693","archive":["Portico"],"relation":{},"ISSN":["0886-0440"],"issn-type":[{"value":"0886-0440","type":"print"}],"subject":[],"published":{"date-parts":[[2016,1,19]]}}}