{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T00:25:53Z","timestamp":1788395153478,"version":"build-2803163510"},"reference-count":28,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2019,9,11]],"date-time":"2019-09-11T00:00:00Z","timestamp":1568160000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Cardiac Surgery"],"published-print":{"date-parts":[[2019,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Arterial switch operation (ASO) is nowadays the standard of care for neonates with D\u2010transposition of the great arteries (D\u2010TGA). We evaluated our early and late results with ASO for D\u2010TGA.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>\n                      We collected data on 267 patients with D\u2010TGA, either with intact ventricular septum (D\u2010TGA\/IVS;\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009182, 68%) and with other associated congenital heart malformations (complex D\u2010TGA;\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200985, 32%) that underwent ASO between January 1987 and July 2018.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Median age at ASO was 8 days (interquartile range [IQR], 6\u201012 days). Fifteen patients (5.6%) died in hospital (6\/182 with D\u2010TGA\/IVS, 3.3% and 9\/85 with complex D\u2010TGA, 11%;\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.02). Median follow\u2010up time was 10.2 years (IQR, 3.7\u201018 years). There were 2 (0.8%) late sudden deaths. Overall survival at 10 and 20 years was 94% and 93%, respectively. Thirty\u2010five patients (14%) required either reoperations or reinterventions, mainly for right ventricular outflow tract obstruction (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200928, 11%). Freedom from reoperation\/reintervention at 10 and 20 years was 87% and 78%, respectively. All patients were in NYHA I at latest clinical examination. Six over 173 patients (3.4%) who underwent a postoperative evaluation of their coronaries presented acquired anomalies. Forty\u2010four patients (17%) who performed a cardiopulmonary exercise testing (CPET) have a predicted VO\n                      <jats:sub>2<\/jats:sub>\n                      comparable to normal peers.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The results of ASO for D\u2010TGA are excellent, with a fairly low mortality and reoperation\/reintervention rate. Functional capacity evaluated with CPET is comparable to normal peers. Continuous follow\u2010up for detecting asymptomatic acquired coronary artery disease is mandatory. A reassessment of competitive sport eligibility criteria for specific D\u2010TGA patients should be considered.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jocs.14045","type":"journal-article","created":{"date-parts":[[2019,9,11]],"date-time":"2019-09-11T06:23:50Z","timestamp":1568183030000},"page":"1154-1161","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Arterial switch operation for transposition of the great arteries: A single\u2010centre 32\u2010year experience"],"prefix":"10.1155","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1829-0259","authenticated-orcid":false,"given":"Vladimiro L.","family":"Vida","sequence":"first","affiliation":[{"name":"Department of Cardiac, Thoracic and Vascular Sciences and Public Health, Paediatric and Congenital Cardiac Surgery Unit University of Padua  Padua Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lorenza","family":"Zanotto","sequence":"additional","affiliation":[{"name":"Department of Cardiac, Thoracic and Vascular Sciences and Public Health, Paediatric and Congenital Cardiac Surgery Unit University of Padua  Padua Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucia","family":"Zanotto","sequence":"additional","affiliation":[{"name":"Department of Statistical Sciences University of Padua  Padua Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura T.","family":"Triglia","sequence":"additional","affiliation":[{"name":"Department of Cardiac, Thoracic and Vascular Sciences and Public Health, Paediatric and Congenital Cardiac Surgery Unit University of Padua  Padua Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ermanno","family":"Bellanti","sequence":"additional","affiliation":[{"name":"Department of Cardiac, Thoracic and Vascular Sciences and Public Health, Paediatric and Congenital Cardiac Surgery Unit University of Padua  Padua Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Biagio","family":"Castaldi","sequence":"additional","affiliation":[{"name":"Department of Child and Woman's Health, Paediatric Cardiology Unit University of Padua  Padua Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0343-8118","authenticated-orcid":false,"given":"Massimo A.","family":"Padalino","sequence":"additional","affiliation":[{"name":"Department of Cardiac, Thoracic and Vascular Sciences and Public Health, Paediatric and Congenital Cardiac Surgery Unit University of Padua  Padua Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Gasperetti","sequence":"additional","affiliation":[{"name":"Department of Medicine, Sports and Exercise Medicine Division University of Padua  Padua Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesca","family":"Battista","sequence":"additional","affiliation":[{"name":"Department of Medicine, Sports and Exercise Medicine Division University of Padua  Padua Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maurizio","family":"Varnier","sequence":"additional","affiliation":[{"name":"Department of Medicine, Sports and Exercise Medicine Division University of Padua  Padua Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovanni","family":"Stellin","sequence":"additional","affiliation":[{"name":"Department of Cardiac, Thoracic and Vascular Sciences and Public Health, Paediatric and Congenital Cardiac Surgery Unit University of Padua  Padua Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,9,11]]},"reference":[{"key":"e_1_2_5_1_2_1","doi-asserted-by":"publisher","DOI":"10.1186\/1750-1172-3-27"},{"key":"e_1_2_5_1_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00246-012-0306-8"},{"key":"e_1_2_5_1_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cardfail.2003.10.005"},{"key":"e_1_2_5_1_5_1","volume-title":"Principles of Exercise Testing and Interpretation: Including Pathophysiology and Clinical Applications","author":"Wasserman K","year":"1999"},{"key":"e_1_2_5_1_6_1","unstructured":"R Core TeamR: A Language and Environment for Statistical Computing. 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