{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,18]],"date-time":"2025-11-18T08:31:15Z","timestamp":1763454675329,"version":"3.45.0"},"reference-count":19,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2019,8,23]],"date-time":"2019-08-23T00:00:00Z","timestamp":1566518400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100004775","name":"Natural Science Foundation of Gansu Province","doi-asserted-by":"publisher","award":["18JR3RA349"],"award-info":[{"award-number":["18JR3RA349"]}],"id":[{"id":"10.13039\/501100004775","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Cardiac Surgery"],"published-print":{"date-parts":[[2019,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>The purpose of this study was to determine the predictors of early left ventricular (LV) dysfunction in patients with rheumatic heart disease (RHD) after mitral valve replacement (MVR). We examined echocardiographic and nonechocardiographic predictors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This study included 571 patients receiving MVR for RHD from 2012 to 2017. Their baseline characters, preoperative examination, operation data, and postoperative echocardiography were collected retrospectively. Univariate and multivariate logistic regression were used to evaluate the predictors of early LV dysfunction after MVR. The LV dysfunction was defined as left ventricular end\u2010ejection fraction (LVEF) &lt;50%. The interaction model was further performed to calculate interaction effects between predictors selected by logistic regression.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      In the 571 patients, 164 (28.7%) had early LV dysfunction after the operation, but only 94 (16.5%) had a preoperative LVEF &lt;50%. Significant differences between two groups (LVEF \u226550% or LVEF &lt;50%) were finally revealed in LV end\u2010diastolic dimension, preoperative atrial fibrillation (AF), preoperative LVEF &lt;50%, and the white blood cell (WBC) count measured after admission (&gt;10\u2009\u00d7\u200910\n                      <jats:sup>9<\/jats:sup>\n                      L\n                      <jats:sup>\u22121<\/jats:sup>\n                      ) in the multivariate logistic regression. Corresponding odds ratios (ORs) were 1.06, 1.82, 3.63, and 2.64, respectively. Diabetes, lesion type, LV end\u2010systolic dimension, aspartate transaminase, alanine transaminase, and serum creatinine were statistically significant (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u2009.05) in univariate logistic regression, with matched ORs 2.45, 1.66\/0.65, 1.07, 2.50, 1.83, and 2.90, respectively. However, these variables were not significant anymore in the multivariate logistic model. Besides, the OR of early postoperative LV dysfunction increased to 7.00 when preoperative AF, preoperative LVEF &lt;50%, and WBC &gt;10\u2009\u00d7\u200910\n                      <jats:sup>9<\/jats:sup>\n                      L\n                      <jats:sup>\u22121<\/jats:sup>\n                      were all present.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The preoperative LV dysfunction, a large LV volume, AF and over\u2010normal WBC could independently predict postoperative LV dysfunction.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jocs.14215","type":"journal-article","created":{"date-parts":[[2019,8,23]],"date-time":"2019-08-23T05:31:10Z","timestamp":1566538270000},"page":"1185-1193","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Predictors of early left ventricular dysfunction after mitral valve replacement for rheumatic valvular disease"],"prefix":"10.1155","volume":"34","author":[{"given":"Xin","family":"Li","sequence":"first","affiliation":[{"name":"The First Clinical Medical College Lanzhou University Lanzhou China"},{"name":"Department of Cardiac Surgery The First Hospital of Lanzhou University Lanzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kaifang","family":"Bao","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Statistics, School of Public Health Lanzhou University Lanzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rongyan","family":"Zhu","sequence":"additional","affiliation":[{"name":"The First Clinical Medical College Lanzhou University Lanzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Quan","family":"Qi","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery The First Hospital of Lanzhou University Lanzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shidong","family":"Liu","sequence":"additional","affiliation":[{"name":"The First Clinical Medical College Lanzhou University Lanzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Han","family":"Li","sequence":"additional","affiliation":[{"name":"The First Clinical Medical College Lanzhou University Lanzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5895-5446","authenticated-orcid":false,"given":"Bing","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery The First Hospital of Lanzhou University Lanzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,8,23]]},"reference":[{"key":"e_1_2_9_1_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(11)61171-9"},{"key":"e_1_2_9_1_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(09)60692-9"},{"key":"e_1_2_9_1_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hlc.2011.08.010"},{"key":"e_1_2_9_1_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2014.02.536"},{"key":"e_1_2_9_1_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2013.08.073"},{"key":"e_1_2_9_1_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(84)80006-6"},{"key":"e_1_2_9_1_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2007.10.067"},{"key":"e_1_2_9_1_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(03)00649-1"},{"key":"e_1_2_9_1_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(93)90840-W"},{"key":"e_1_2_9_1_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/ehjci\/jes155"},{"key":"e_1_2_9_1_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2008.09.023"},{"key":"e_1_2_9_1_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2011.11.034"},{"key":"e_1_2_9_1_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejechocard\/jer128"},{"key":"e_1_2_9_1_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(02)01922-8"},{"key":"e_1_2_9_1_16_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.90.2.830"},{"key":"e_1_2_9_1_17_1","first-page":"5063","article-title":"Systemic inflammation is associated with myocardial fibrosis, diastolic dysfunction, and cardiac hypertrophy in patients with hypertrophic cardiomyopathy","volume":"9","author":"Fang L","year":"2017","journal-title":"Am J Transl Res"},{"key":"e_1_2_9_1_18_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2017.00572"},{"key":"e_1_2_9_1_19_1","doi-asserted-by":"publisher","DOI":"10.1186\/1475-2840-6-14"},{"key":"e_1_2_9_1_20_1","doi-asserted-by":"publisher","DOI":"10.1089\/met.2017.0060"}],"container-title":["Journal of Cardiac Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocs.14215","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jocs.14215","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocs.14215","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,18]],"date-time":"2025-11-18T08:28:51Z","timestamp":1763454531000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jocs.14215"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,8,23]]},"references-count":19,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2019,11]]}},"alternative-id":["10.1111\/jocs.14215"],"URL":"https:\/\/doi.org\/10.1111\/jocs.14215","archive":["Portico"],"relation":{},"ISSN":["0886-0440"],"issn-type":[{"type":"print","value":"0886-0440"}],"subject":[],"published":{"date-parts":[[2019,8,23]]},"assertion":[{"value":"2019-08-23","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}