{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,26]],"date-time":"2025-11-26T16:37:20Z","timestamp":1764175040735,"version":"3.46.0"},"reference-count":7,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2022,2,13]],"date-time":"2022-02-13T00:00:00Z","timestamp":1644710400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Cardiac Surgery"],"published-print":{"date-parts":[[2022,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>We report an unusual case of black discoloration of an aortic root aneurysm and aortic valve cusps due to homogentisic acid deposition in a patient suffering from alkaptonuria. The patient underwent a valve\u2010sparing aortic root replacement after careful and objective evaluation of the valve cusps. Despite alkaptonuria is classically associated with aortic valve stenosis and replacement, in the present case, the affected valve cusps were suitable for repair. To our knowledge, this is the first reported case of aortic valve\u2010sparing procedure performed in a patient with alkaptonuria.<\/jats:p>","DOI":"10.1111\/jocs.16331","type":"journal-article","created":{"date-parts":[[2022,2,13]],"date-time":"2022-02-13T05:03:37Z","timestamp":1644728617000},"page":"1413-1415","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["The black root: Aortic valve sparing in alkaptonuria"],"prefix":"10.1155","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6708-6617","authenticated-orcid":false,"given":"Giulio","family":"Folino","sequence":"first","affiliation":[{"name":"Department of Cardio\u2010Thoracic and Vascular Sciences University of Padua  Padua Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raffaele","family":"Scaffa","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery European Hospital  Rome Italy"},{"name":"Division of Cardiac Surgery A.O.U. San Giovanni di Dio e Ruggi d'Aragona  Salerno Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Salica","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery European Hospital  Rome Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6094-8280","authenticated-orcid":false,"given":"Luca","family":"Weltert","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery European Hospital  Rome Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Salvo","family":"D'Aleo","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery European Hospital  Rome Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lorenzo","family":"Guerrieri","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery European Hospital  Rome Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Irace","sequence":"additional","affiliation":[{"name":"Department of General and Specialized Surgery Paride Stefanini Sapienza University  Rome Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Enrico","family":"Coscioni","sequence":"additional","affiliation":[{"name":"Division of Cardiac Surgery A.O.U. San Giovanni di Dio e Ruggi d'Aragona  Salerno Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gino","family":"Gerosa","sequence":"additional","affiliation":[{"name":"Department of Cardio\u2010Thoracic and Vascular Sciences University of Padua  Padua Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruggero","family":"De Paulis","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery European Hospital  Rome Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,2,13]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2559.2008.03000.x"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.21037\/jovs.2019.09.02"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10545-011-9339-z"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymgme.2011.10.017"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/jocs.12129"},{"key":"e_1_2_6_7_1","first-page":"863","article-title":"Aortic valve regurgitation in alkaptonuria","volume":"13","author":"Yoshikai M","year":"2004","journal-title":"J Heart Valve Dis"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2012.07.058"}],"container-title":["Journal of Cardiac Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocs.16331","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jocs.16331","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocs.16331","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,26]],"date-time":"2025-11-26T16:31:59Z","timestamp":1764174719000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jocs.16331"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,2,13]]},"references-count":7,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2022,5]]}},"alternative-id":["10.1111\/jocs.16331"],"URL":"https:\/\/doi.org\/10.1111\/jocs.16331","archive":["Portico"],"relation":{},"ISSN":["0886-0440"],"issn-type":[{"type":"print","value":"0886-0440"}],"subject":[],"published":{"date-parts":[[2022,2,13]]},"assertion":[{"value":"2022-01-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-01-28","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-02-13","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}