{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:12:05Z","timestamp":1787015525919,"version":"build-2736575974"},"reference-count":40,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2022,6,9]],"date-time":"2022-06-09T00:00:00Z","timestamp":1654732800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Cardiac Surgery"],"published-print":{"date-parts":[[2022,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>In this study, it was aimed to compare various parameters during surgery and postoperative cognitive functions in patients undergoing coronary artery bypass graft (CABG) surgery using different levels of perioperative oxygen.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      One hundred patients scheduled for elective CABG surgery were included in the study. The patients were divided into two groups according to arterial oxygen levels during surgery. In the normoxia group (NG) (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200950), partial arterial oxygen pressure\u00a0(PaO\n                      <jats:sub>2<\/jats:sub>\n                      ) was between \u2265100\u00a0and &lt;180\u2009mmHg with at least 40% fraction of inspired oxygen (FiO\n                      <jats:sub>2<\/jats:sub>\n                      ) mechanical ventilation (MV), and in the hyperoxia group (HG) (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200950), PaO\n                      <jats:sub>2<\/jats:sub>\n                      was \u2265180\u2009mmHg with 100% FiO\n                      <jats:sub>2<\/jats:sub>\n                      MV. Hemodynamic parameters, peripheral oxygen saturation (SpO\n                      <jats:sub>2<\/jats:sub>\n                      ), regional\u00a0cerebral oxygen saturation (rSO\n                      <jats:sub>2<\/jats:sub>\n                      ) measured from bilateral sensors, and blood gas values were recorded at the planned measurement times. Postoperative features (mortality and infection rates, length of stay in the hospital, and intensive care unit) and complications of the patients have been recorded (low cardiac output syndrome, renal failure, delirium). Mini\u2010Mental State Examination (MMSE) test\u00a0was applied to the patients before and at the 12th, 24th\u2009hours; on the first, third, sixth months after surgery.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Extubation time was found to be shorter in NG (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u2009.05). Between the groups, rSO\n                      <jats:sub>2<\/jats:sub>\n                      and mean arterial pressure\u00a0were found to be significantly lower in HG at the time of T4 measurement (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u2009.042,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u2009.038, respectively). MMSE values of the groups at the first, third, and sixth months were found to be significantly higher in NG (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u2009.017,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u2009.014,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u2009.002, respectively).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Hyperoxemia application during CABG may be associated with worse postoperative late\u2010term cognitive functions.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jocs.16661","type":"journal-article","created":{"date-parts":[[2022,6,9]],"date-time":"2022-06-09T06:59:34Z","timestamp":1654757974000},"page":"2552-2563","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Intraoperative hyperoxygenation may negatively affect postoperative cognitive functions in coronary artery bypass graft operations: A randomized controlled study"],"prefix":"10.1155","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5080-4555","authenticated-orcid":false,"given":"Tu\u011fba","family":"Onur","sequence":"first","affiliation":[{"name":"Departmant of Anesthesiology and Reanimation University of Health Sciences Bursa Y\u00fcksek \u0130htisas Training and Research Hospital  Bursa Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5922-2300","authenticated-orcid":false,"given":"\u00dcmran","family":"Karaca","sequence":"additional","affiliation":[{"name":"Departmant of Anesthesiology and Reanimation University of Health Sciences Bursa Y\u00fcksek \u0130htisas Training and Research Hospital  Bursa Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2472-1681","authenticated-orcid":false,"given":"Filiz","family":"Ata","sequence":"additional","affiliation":[{"name":"Departmant of Anesthesiology and Reanimation University of Health Sciences Bursa Y\u00fcksek \u0130htisas Training and Research Hospital  Bursa Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3943-5549","authenticated-orcid":false,"given":"Halil E.","family":"Sayan","sequence":"additional","affiliation":[{"name":"Departmant of Anesthesiology and Reanimation University of Health Sciences Bursa Y\u00fcksek \u0130htisas Training and Research Hospital  Bursa Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3957-922X","authenticated-orcid":false,"given":"An\u0131l","family":"Onur","sequence":"additional","affiliation":[{"name":"Departmant of Anesthesiology and Reanimation University of Health Sciences Bursa Y\u00fcksek \u0130htisas Training and Research Hospital  Bursa Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6626-3626","authenticated-orcid":false,"given":"Canan","family":"Yilmaz","sequence":"additional","affiliation":[{"name":"Departmant of Anesthesiology and Reanimation University of Health Sciences Bursa Y\u00fcksek \u0130htisas Training and Research Hospital  Bursa Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8031-6264","authenticated-orcid":false,"given":"Ay\u015fe N.","family":"Balkaya","sequence":"additional","affiliation":[{"name":"Departmant of Anesthesiology and Reanimation University of Health Sciences Bursa Y\u00fcksek \u0130htisas Training and Research Hospital  Bursa Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C\u00fcneyt","family":"Eri\u015f","sequence":"additional","affiliation":[{"name":"Departmant of Cardiovascular Surgery University of Health Sciences Bursa Y\u00fcksek \u0130htisas Training and Research Hospital  Bursa Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,6,9]]},"reference":[{"key":"e_1_2_9_2_1","first-page":"249","article-title":"The science and practice of cardiopulmonary bypass: from\u00a0cross circulation to ECMO and SIRS","volume":"2013","author":"Punjabi PP","year":"2013","journal-title":"Glob Cardiol Sci Pract"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.108.795260"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2010.707"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2016.11993"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.jvca.2013.03.034"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(96)70069-7"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.117.030308"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejcts.2008.01.012"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200102083440601"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.21899"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/chd.12426"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2044.2002.02826.x"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amsu.2018.09.036"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0102-76382008000200015"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.21470\/1678-9741-2020-0390"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2007.10.083"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00702-011-0758-7"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrd1330"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnen\/60.8.759"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/anae.13218"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2016.12.039"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.18632\/aging.103058"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13063-017-2337-1"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/nicc.12492"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1177\/0267659111425621"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.jvca.2013.03.034"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/0149-7634(95)00080-1"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.5606\/tgkdc.dergisi.2013.6129"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.jvca.2010.05.003"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0b013e318215217e"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1213\/01.ane.0000166974.96219.cd"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.5152\/TJAR.2016.26092016"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1111\/anae.12634"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.jvca.2010.03.019"},{"key":"e_1_2_9_36_1","article-title":"Cerebral near\u2010infrared spectroscopy (NIRS) for perioperative monitoring of brain oxygenation in children and adults","volume":"1","author":"Yu Y","year":"2018","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2017-016613"},{"key":"e_1_2_9_38_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12630-018-1065-7"},{"key":"e_1_2_9_39_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejcts\/ezu193"},{"key":"e_1_2_9_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(98)70134-5"},{"key":"e_1_2_9_41_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13613-017-0246-9"}],"container-title":["Journal of Cardiac Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocs.16661","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jocs.16661","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocs.16661","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T14:03:55Z","timestamp":1762524235000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jocs.16661"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,6,9]]},"references-count":40,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2022,9]]}},"alternative-id":["10.1111\/jocs.16661"],"URL":"https:\/\/doi.org\/10.1111\/jocs.16661","archive":["Portico"],"relation":{"has-preprint":[{"id-type":"doi","id":"10.22541\/au.162306218.89529068\/v1","asserted-by":"object"}]},"ISSN":["0886-0440"],"issn-type":[{"value":"0886-0440","type":"print"}],"subject":[],"published":{"date-parts":[[2022,6,9]]},"assertion":[{"value":"2021-05-29","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-05-09","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-06-09","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}