{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T19:27:34Z","timestamp":1762543654097,"version":"build-2065373602"},"reference-count":8,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2022,6,11]],"date-time":"2022-06-11T00:00:00Z","timestamp":1654905600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Cardiac Surgery"],"published-print":{"date-parts":[[2022,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>We evaluated the potential of cardiac magnetic resonance (CMR)\u2010derived strain to assess aortic valve (AV) annulus deformation during the cardiac cycle in regurgitant and well\u2010functioning AVs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Four patients with severe aortic regurgitation and seven healthy controls underwent CMR. Assessment of longitudinal strain was performed by hypothesizing the AV annulus would be the left ventricle in long\u2010axis orientation. Longitudinal strain of the segments belonging to the muscular and fibrous AV annulus was weighted and averaged to obtain regional values (RLS).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Comparison of RLS between regurgitant and well\u2010functioning AVs showed a considerably different deformation of the muscular AV annulus (i.e., median RLS: 4.18 % [patients] vs. \u221210.41 % [controls],\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u2009.024). The fibrous AV annulus demonstrated comparable deformational changes in both groups.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>CMR\u2010derived strain allows for quantification of AV annulus deformation during the cardiac cycle and shows an altered RLS in the muscular AV annulus in patients with severe aortic regurgitation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jocs.16683","type":"journal-article","created":{"date-parts":[[2022,6,12]],"date-time":"2022-06-12T01:19:05Z","timestamp":1654996745000},"page":"2734-2737","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["A novel technique to quantify aortic valve annulus deformation: A pilot study"],"prefix":"10.1155","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8057-9555","authenticated-orcid":false,"given":"Theresa","family":"Holst","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Surgery University Heart and Vascular Center UKE Hamburg Hamburg Germany"},{"name":"Department of Cardiothoracic Surgery Augsburg University Hospital Augsburg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3415-3385","authenticated-orcid":false,"given":"Johannes","family":"Petersen","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery University Heart and Vascular Center UKE Hamburg Hamburg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gerhard","family":"Adam","sequence":"additional","affiliation":[{"name":"Department of Diagnostic and Interventional Radiology and Nuclear Medicine University Hospital Hamburg Eppendorf Hamburg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hermann","family":"Reichenspurner","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery University Heart and Vascular Center UKE Hamburg Hamburg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Evaldas","family":"Girdauskas","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery University Heart and Vascular Center UKE Hamburg Hamburg Germany"},{"name":"Department of Cardiothoracic Surgery Augsburg University Hospital Augsburg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Enver","family":"Tahir","sequence":"additional","affiliation":[{"name":"Department of Diagnostic and Interventional Radiology and Nuclear Medicine University Hospital Hamburg Eppendorf Hamburg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,6,11]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mayocp.2018.11.034"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2010.12.006"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejcts\/ezy099"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.21037\/qims.2020.03.16"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrcardio.2017.1"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1253\/circj.CJ-18-1388"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1161\/hc0402.102975"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12968-017-0333-y"}],"container-title":["Journal of Cardiac Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocs.16683","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jocs.16683","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocs.16683","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T14:04:32Z","timestamp":1762524272000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jocs.16683"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,6,11]]},"references-count":8,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2022,9]]}},"alternative-id":["10.1111\/jocs.16683"],"URL":"https:\/\/doi.org\/10.1111\/jocs.16683","archive":["Portico"],"relation":{},"ISSN":["0886-0440"],"issn-type":[{"type":"print","value":"0886-0440"}],"subject":[],"published":{"date-parts":[[2022,6,11]]},"assertion":[{"value":"2022-03-27","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication 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