{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T14:09:34Z","timestamp":1762524574226,"version":"build-2065373602"},"reference-count":8,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2022,6,15]],"date-time":"2022-06-15T00:00:00Z","timestamp":1655251200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Cardiac Surgery"],"published-print":{"date-parts":[[2022,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>We present the case of a 69 years old man affected by Aarskog\u2013Scott syndrome. He came to our attention for an aneurysm of the aortic root, with almost moderate aortic regurgitation; moderate mitral regurgitation was discovered during preoperative assessment.\u00a0We performed a modified Bentall's procedure and mitral valve repair. A patent foramen ovale was closed.\u00a0Aarskog\u2013Scott syndrome is a complex developmental disorder, characterized by X\u2010linked recessive hereditariness short stature, craniofacial abnormalities, hyperextension of the proximal interphalangeal joints, and genital malformations. Diagnosis is still a challenge, in light of various clinical pictures and features in common with other syndromes (i.e., Noonan, SHORT, and Robinow syndromes).\u00a0It has been longly debated if cardiac surveillance is needed among the affected patients; it should be probably undertaken, in view of the higher incidence of congenital heart disease. Moreover, the presence of extremely flexible joints suggests the coexistence of a connective tissue disorder.<\/jats:p>","DOI":"10.1111\/jocs.16684","type":"journal-article","created":{"date-parts":[[2022,6,15]],"date-time":"2022-06-15T07:20:10Z","timestamp":1655277610000},"page":"2897-2899","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Aortic root aneurysm in a patient with Aarskog\u2013Scott syndrome"],"prefix":"10.1155","volume":"37","author":[{"given":"Sofia","family":"Martin\u2010Suarez","sequence":"first","affiliation":[{"name":"Division of Cardiac Surgery, IRCCS, S. Orsola Hospital University of Bologna  Bologna Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vincenzo","family":"Pagano","sequence":"additional","affiliation":[{"name":"Division of Cardiac Surgery, IRCCS, S. Orsola Hospital University of Bologna  Bologna Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Campanini","sequence":"additional","affiliation":[{"name":"Division of Cardiac Surgery, IRCCS, S. Orsola Hospital University of Bologna  Bologna Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Riccardo","family":"Nania","sequence":"additional","affiliation":[{"name":"Division of Cardiac Surgery, IRCCS, S. Orsola Hospital University of Bologna  Bologna Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonino","family":"Costantino","sequence":"additional","affiliation":[{"name":"Division of Cardiac Surgery, IRCCS, S. Orsola Hospital University of Bologna  Bologna Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Davide","family":"Pacini","sequence":"additional","affiliation":[{"name":"Division of Cardiac Surgery, IRCCS, S. Orsola Hospital University of Bologna  Bologna Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,6,15]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(70)80247-5"},{"key":"e_1_2_7_3_1","first-page":"240","article-title":"Unusual facies, joint hypermobility, genital anomaly and short stature: a new dysmorphic syndrome","volume":"7","author":"Scott CI","year":"1971","journal-title":"Birth Defects Orig Artic Ser"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.3934\/genet.2016.1.49"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1091\/mbc.E08-11-1136"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320500404"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1510\/icvts.2004.089672"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.4103\/sja.sja_1047_20"},{"key":"e_1_2_7_9_1","doi-asserted-by":"crossref","unstructured":"DrumondVZ SalgadoLS SalgadoCS et al.The prevalence of clinical features in patients with Aarskog\u2013Scott syndrome and assessment of genotype\u2010phenotype correlation: a systematic review.Genetics Research.2021.https:\/\/doi.org\/10.1155\/2021\/6652957","DOI":"10.1155\/2021\/6652957"}],"container-title":["Journal of Cardiac Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocs.16684","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jocs.16684","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocs.16684","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T14:04:34Z","timestamp":1762524274000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jocs.16684"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,6,15]]},"references-count":8,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2022,9]]}},"alternative-id":["10.1111\/jocs.16684"],"URL":"https:\/\/doi.org\/10.1111\/jocs.16684","archive":["Portico"],"relation":{},"ISSN":["0886-0440"],"issn-type":[{"type":"print","value":"0886-0440"}],"subject":[],"published":{"date-parts":[[2022,6,15]]},"assertion":[{"value":"2022-04-15","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-05-04","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-06-15","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}