{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T12:38:22Z","timestamp":1791463102430,"version":"4.3.4"},"reference-count":30,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2013,2,4]],"date-time":"2013-02-04T00:00:00Z","timestamp":1359936000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2013,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To determine the risk of cesarean delivery after induction of labor with prostaglandins and to establish if this is influenced by a single indication of induction of labor or any intrinsic characteristic of the woman or labor.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and Methods<\/jats:title><jats:p>A retrospective cohort study was carried out. Three hundred and twenty\u2010four pregnant women who underwent pharmacological induction of labor with prostaglandins were divided into nine groups through indication of labor induction. Statistical analysis was assessed with the <jats:styled-content style=\"fixed-case\">K<\/jats:styled-content>olmogorov\u2013<jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>mirnov test to assess the normal distribution of variables, <jats:styled-content style=\"fixed-case\">K<\/jats:styled-content>ruskal\u2013<jats:styled-content style=\"fixed-case\">W<\/jats:styled-content>allis test for comparisons of non\u2010parametric continuous variables, univariate analysis to compare cesarean delivery rates and multivariate logistic regression.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The risk of cesarean section was significantly higher only in prolonged pregnancy (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>\u2009=\u20091.98; 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>: 1.18\u20133.34). Elective induction was associated with the lowest risk of cesarean section (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>\u2009=\u20090.46; 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>: 0.26\u20130.81). Maternal age and was directly related (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>\u2009=\u20091.087; 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>: 1.016\u20131.164), while parity (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>\u2009=\u20090.123; 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>: 0.051\u20130.332), <jats:styled-content style=\"fixed-case\">B<\/jats:styled-content>ishop score (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>\u2009=\u20090.703; 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>: 0.571\u20130.884), and duration of labor (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>\u2009=\u20090.995; 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>: 0.993\u20130.998) were inversely correlated with cesarean delivery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Cesarean delivery rate is not significantly influenced by any indication of induction of labor with prostaglandins, except for prolonged pregnancy. Elective induction is associated with the lowest risk of cesarean section. Increasing maternal age, low parity, low <jats:styled-content style=\"fixed-case\">B<\/jats:styled-content>ishop score and low duration of labor are at higher risk of cesarean section.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jog.12000","type":"journal-article","created":{"date-parts":[[2013,2,5]],"date-time":"2013-02-05T04:18:56Z","timestamp":1360037936000},"page":"926-931","source":"Crossref","is-referenced-by-count":15,"title":["Single indications of induction of labor with prostaglandins and risk of cesarean delivery: A retrospective cohort study"],"prefix":"10.1111","volume":"39","author":[{"given":"Sandro","family":"Gerli","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology University of Perugia  Perugia Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandro","family":"Favilli","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology University of Perugia  Perugia Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia","family":"Giordano","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology University of Perugia  Perugia Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vittorio","family":"Bini","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology University of Perugia  Perugia Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gian Carlo","family":"Di Renzo","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology University of Perugia  Perugia Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,2,4]]},"reference":[{"issue":"1","key":"e_1_2_6_2_1","first-page":"387","article-title":"Practice Bulletin No. 107: Induction of labor","volume":"114","author":"American College of Obstetrician and Gynecologist","year":"2009","journal-title":"Obstet Gynecol"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2010.02754.x"},{"key":"e_1_2_6_4_1","first-page":"1","article-title":"Births: Final data for 2009","volume":"60","author":"Martin JA","year":"2011","journal-title":"Natl Vital Stat Rep"},{"key":"e_1_2_6_5_1","first-page":"1","article-title":"Births: Final data for 2005","volume":"56","author":"Martin JA","year":"2007","journal-title":"Natl Vital Stat Rep"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0029-7844(02)02047-1"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2004.07.001"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e31820caf12"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(94)70269-1"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199206113262402"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(92)91558-R"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006250-200006000-00026"},{"issue":"2","key":"e_1_2_6_13_1","article-title":"Interventions for preventing or improving outcome delivery at or beyond term","author":"Crowley P","year":"2000","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e3181e10c5c"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0029-7844(97)00259-7"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0029-7844(98)00115-X"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2010.02602.x"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0029-7844(99)00377-4"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006250-200308000-00014"},{"key":"e_1_2_6_20_1","unstructured":"Ministero del lavoro della salute e delle politiche sociali Direzione generale della programmazione sanitaria dei livelli di assistenza e dei principi etici di sistema. 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