{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T20:49:31Z","timestamp":1760906971431},"reference-count":8,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2013,3,20]],"date-time":"2013-03-20T00:00:00Z","timestamp":1363737600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2013,5]]},"abstract":"Abstract<\/jats:title>Aim<\/jats:title>Second\u2010trimester maternal serum screening (MSS<\/jats:styled-content>) is the predominant form of prenatal screening in J<\/jats:styled-content>apan. We hypothesize that patient education and physician knowledge of D<\/jats:styled-content>own syndrome (DS<\/jats:styled-content>) screening are insufficient to provide adequate information regarding prenatal screening in J<\/jats:styled-content>apan.<\/jats:p><\/jats:sec>Material and Methods<\/jats:title>In\u2010person or telephone interviews with medical personnel were conducted at 25 medical facilities utilizing Afp4<\/jats:sup><\/jats:styled-content> (E<\/jats:styled-content>soterix G<\/jats:styled-content>enetic L<\/jats:styled-content>aboratories, LLC<\/jats:styled-content>, a wholly\u2010owned subsidiary of L<\/jats:styled-content>aboratory C<\/jats:styled-content>orporation of A<\/jats:styled-content>merica H<\/jats:styled-content>oldings) second trimester screening. We explored how medical facilities provided information about the MSS<\/jats:styled-content> process to pregnant women.<\/jats:p><\/jats:sec>Results<\/jats:title>Before prenatal testing, 60% of medical facilities spent an average of less than 5\u2009min per patient explaining the MSS<\/jats:styled-content> process. The option of amniocentesis for chromosomal aneuploidy was explained at nearly all facilities, but only 60% explained the risk of amniocentesis. Ultrasound examination for open neural tube defects was explained only at half the facilities. Only five of 25 (20%) medical practitioners explained the possibility of having congenital disorders fetus.<\/jats:p><\/jats:sec>Conclusion<\/jats:title>This study revealed that most obstetricians in J<\/jats:styled-content>apan do not provide their patients with sufficient information about MSS<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jog.12015","type":"journal-article","created":{"date-parts":[[2013,3,20]],"date-time":"2013-03-20T07:59:09Z","timestamp":1363766349000},"page":"942-947","source":"Crossref","is-referenced-by-count":4,"title":["Survey of second\u2010trimester maternal serum screening in J<\/scp>apan"],"prefix":"10.1111","volume":"39","author":[{"given":"Torayuki","family":"Okuyama","sequence":"first","affiliation":[{"name":"Clinical Laboratory Medicine National Center for Child Health and Development Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junko","family":"Yotsumoto","sequence":"additional","affiliation":[{"name":"Clinical Laboratory Medicine National Center for Child Health and Development Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yumi","family":"Funato","sequence":"additional","affiliation":[{"name":"LabCorp Japan, G.K. Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,3,20]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.297.6653.883"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0223(199608)16:8<713::AID-PD933>3.0.CO;2-X"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1447-0756.2000.tb01306.x"},{"key":"e_1_2_8_5_1","unstructured":"Opinions concerning tests using maternal serum markers. the Committee on Prenatal Diagnosis the Advanced Clinical Technology Evaluation Task Force of the Ministry of Health and Welfare 1999."},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2008.01700.x"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006250-200701000-00054"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1701-2163(16)32379-9"},{"key":"e_1_2_8_9_1","unstructured":"The statement concerning prenatal testing and diagnostics. Japan Society of Obstetrics and Gynecology 2011."}],"container-title":["Journal of Obstetrics and Gynaecology Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjog.12015","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjog.12015","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jog.12015","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,15]],"date-time":"2023-10-15T04:13:50Z","timestamp":1697343230000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1111\/jog.12015"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,3,20]]},"references-count":8,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2013,5]]}},"alternative-id":["10.1111\/jog.12015"],"URL":"https:\/\/doi.org\/10.1111\/jog.12015","archive":["Portico"],"relation":{},"ISSN":["1341-8076","1447-0756"],"issn-type":[{"value":"1341-8076","type":"print"},{"value":"1447-0756","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,3,20]]}}}