{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:14:25Z","timestamp":1787015665742,"version":"build-2736575974"},"reference-count":12,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2013,9,5]],"date-time":"2013-09-05T00:00:00Z","timestamp":1378339200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2014,1]]},"abstract":"Abstract<\/jats:title>\n \n Clinical outcome of confined placental mosaicism (\n CPM<\/jats:styled-content>\n ) is varied, from normal pregnancy to intrauterine fetal death. It has been suggested that\n CPM<\/jats:styled-content>\n for trisomy 2 is less likely to cause serious adverse effect on pregnancy. We hereby report a case of\n CPM<\/jats:styled-content>\n for trisomy 2, which presented severe fetal growth restriction (\n FGR<\/jats:styled-content>\n ) and placental abnormalities. A 30\u2010year\u2010old woman was referred to our hospital at 17\n +2<\/jats:sup>\n weeks because of marked\n FGR<\/jats:styled-content>\n . Ultrasonography demonstrated prominent placental hypertrophy with multiple focal defects without any fetal structural abnormalities. Amniocentesis at 18\n +3<\/jats:sup>\n weeks revealed normal karyotype. Fetal growth rate worsened with gestational weeks, reaching \u22127 standard deviation at 36 weeks. At 37 weeks, the fetal condition suddenly deteriorated, ending in a stillbirth of a 756\u2010g female baby. Postnatal cytogenetic analysis by array comparative genomic hybridization revealed trisomy 2 of the chorionic villi, and\n CPM<\/jats:styled-content>\n for trisomy 2 was suggested as the cause of\n FGR<\/jats:styled-content>\n and placental abnormalities.\n <\/jats:p>","DOI":"10.1111\/jog.12145","type":"journal-article","created":{"date-parts":[[2013,9,5]],"date-time":"2013-09-05T04:33:23Z","timestamp":1378355603000},"page":"279-283","source":"Crossref","is-referenced-by-count":11,"title":["Placental abnormalities detected by ultrasonography in a case of confined placental mosaicism for trisomy 2 with severe fetal growth restriction"],"prefix":"10.1111","volume":"40","author":[{"given":"Takeshi","family":"Nagamatsu","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology The University of Tokyo Hospital Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshimasa","family":"Kamei","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology The University of Tokyo Hospital Tokyo Japan"},{"name":"Department of Obstetrics and Gynecology Saitama Medical University Saitama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takahiro","family":"Yamashita","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology The University of Tokyo Hospital Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomoyuki","family":"Fujii","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology The University of Tokyo Hospital Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shiro","family":"Kozuma","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology The University of Tokyo Hospital Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,9,5]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.3109\/15513819009067097"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0223(199705)17:5<443::AID-PD82>3.0.CO;2-2"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.2457"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0223(199610)16:10<899::AID-PD960>3.0.CO;2-M"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.644"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/1096-8628(20001218)95:5<454::AID-AJMG9>3.0.CO;2-O"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.38.3.214"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.1430"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1701-2163(16)34239-6"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.1970120304"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0223(199812)18:12<1308::AID-PD443>3.0.CO;2-H"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.2409"}],"container-title":["Journal of Obstetrics and Gynaecology Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjog.12145","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjog.12145","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jog.12145","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,2]],"date-time":"2023-10-02T13:54:30Z","timestamp":1696254870000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1111\/jog.12145"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,9,5]]},"references-count":12,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2014,1]]}},"alternative-id":["10.1111\/jog.12145"],"URL":"https:\/\/doi.org\/10.1111\/jog.12145","archive":["Portico"],"relation":{},"ISSN":["1341-8076","1447-0756"],"issn-type":[{"value":"1341-8076","type":"print"},{"value":"1447-0756","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,9,5]]}}}