{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T23:50:35Z","timestamp":1784332235023,"version":"3.55.0"},"reference-count":20,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2013,9,19]],"date-time":"2013-09-19T00:00:00Z","timestamp":1379548800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2014,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>The aim of this study was to compare the semen parameters of diabetic husbands of infertile couples with those of non\u2010diabetic husbands of proven fertility.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and Methods<\/jats:title><jats:p>Assuming a 5% fall in <jats:styled-content style=\"fixed-case\">DNA<\/jats:styled-content> integrity of sperms would affect fertility, the required sample size calculated was 103, with 80% power and 5% level of significance. During the study period (<jats:styled-content style=\"fixed-case\">J<\/jats:styled-content>anuary 2010 to <jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>ay 2012), 52 husbands were found to have diabetes mellitus, by 2\u2010h\/post 75 g of glucose load (\u2265200\u2009mg %). Glycosylated hemoglobin level in each case was found to be more than 6.5% (study group). During the same period, six couples with infertility conceived spontaneously while undergoing evaluations, 60 couples conceived following treatment of ovulatory disorders in wives and all had ongoing pregnancies (more than 12 weeks). Husbands of these 66 couples were found to be non\u2010diabetic (control group). Conventional semen analysis (<jats:styled-content style=\"fixed-case\">W<\/jats:styled-content>orld <jats:styled-content style=\"fixed-case\">H<\/jats:styled-content>ealth <jats:styled-content style=\"fixed-case\">O<\/jats:styled-content>rganization criteria), hypo\u2010osmotic swelling test and <jats:styled-content style=\"fixed-case\">DNA<\/jats:styled-content> integrity test (<jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>cridine <jats:styled-content style=\"fixed-case\">O<\/jats:styled-content>range test) were done in all cases. <jats:styled-content style=\"fixed-case\">B<\/jats:styled-content>ody mass index was measured in each case.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There were no differences in the mean age and body mass index between the two groups but significant differences were found in the following parameters: volume of the ejaculate (<jats:italic>P<\/jats:italic>\u2009=\u20090.004); total cells per ejaculate (<jats:italic>P<\/jats:italic>\u2009=\u20090.01); percent motility (<jats:italic>P<\/jats:italic>\u2009=\u20090.0001); total motile cells per ejaculate (<jats:italic>P<\/jats:italic>\u2009=\u20090.0001); percent of rapid progressive motility (<jats:italic>P<\/jats:italic>\u2009=\u20090.0001); percent normal morphology (<jats:italic>P<\/jats:italic>\u2009=\u20090.02); percent hypo\u2010osmotic swelling test (0.0001); and percent normal <jats:styled-content style=\"fixed-case\">DNA<\/jats:styled-content> integrity (<jats:italic>P<\/jats:italic>\u2009=\u20090.0001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Diabetes mellitus can affect spermatogenesis at various levels, which can cause male\u2010factor infertility.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jog.12149","type":"journal-article","created":{"date-parts":[[2013,10,8]],"date-time":"2013-10-08T16:40:18Z","timestamp":1381250418000},"page":"167-171","source":"Crossref","is-referenced-by-count":47,"title":["Diabetes mellitus and abnormalities in semen analysis"],"prefix":"10.1111","volume":"40","author":[{"given":"Sudhindra Mohan","family":"Bhattacharya","sequence":"first","affiliation":[{"name":"S.C.Das Memorial Medical and Research Center Jodhpur Park  Kolkata India"},{"name":"Department of Obstetrics and Gynecology KPC Medical College  Jadavpur Kolkata India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mainak","family":"Ghosh","sequence":"additional","affiliation":[{"name":"Department of Pharmacology Murshidabad Medical College  West Bengal India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nupur","family":"Nandi","sequence":"additional","affiliation":[{"name":"Department of Obstetrics 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