{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T17:01:22Z","timestamp":1787850082107,"version":"build-2784847793"},"reference-count":18,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2013,10,10]],"date-time":"2013-10-10T00:00:00Z","timestamp":1381363200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2014,2]]},"abstract":"Abstract<\/jats:title>Aim<\/jats:title>The objective of this study was to review our experience with ectopic pregnancy management and to evaluate major predictive factors for failure of conservative linear salpingostomy.<\/jats:p><\/jats:sec>Methods<\/jats:title>Seven hundred and ninety\u2010seven cases that were treated for ectopic pregnancy in our clinic between O<\/jats:styled-content>ctober 2005 and S<\/jats:styled-content>eptember 2011 were analyzed retrospectively for incidence and treatment options. We defined failure as rising or plateauing postoperative serum \u03b2\u2010hCG<\/jats:styled-content> levels that required additional medical or surgical treatment after initial removal of the ectopic pregnancy by laparoscopy or by laparotomy. We examined the risk factors consisting of preoperative \u03b2\u2010hCG<\/jats:styled-content>, size and location of ectopic lesions, the presence of fetal heart beat and tubal condition that can influence the failure or success of conservative salpingostomy.<\/jats:p><\/jats:sec>Results<\/jats:title>In total, 403 patients were treated conservatively. These conservative managements consist of 334 salpingostomies performed by laparoscopy and 69 by laparotomy. Because of persistent ectopic pregnancy, 16 patients underwent medical treatment. In total, 387 patients were treated successfully with conservative management and 16 patients were treated unsuccessfully with conservative management. When variables of P<\/jats:styled-content><\/jats:italic>\u2009<\u20090.05 were subjected to multivariate analysis, size of the ectopic pregnancy of 33.5\u2009mm or greater and fimbrial and isthmic region ectopic pregnancies were significantly associated with the failure rate.<\/jats:p><\/jats:sec>Conclusions<\/jats:title>The size of the ectopic pregnancy and fimbrial and isthmic region ectopic pregnancies were determinant of failure of conservative surgery. Our success rate in the ruptured group is not an underestimated value to dissuade patients wishing to maintain fertility by undergoing salpingectomy. So, the conservative approach to ectopic pregnancy should be undertaken after careful patient evaluation.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jog.12187","type":"journal-article","created":{"date-parts":[[2013,10,12]],"date-time":"2013-10-12T02:20:07Z","timestamp":1381544407000},"page":"453-458","source":"Crossref","is-referenced-by-count":11,"title":["Predictive factors for failure of salpingostomy in ectopic pregnancy"],"prefix":"10.1111","volume":"40","author":[{"given":"Semra","family":"Kayatas","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Zeynep Kamil Women's and Children's Diseases Training and Research Hospital Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oya","family":"Demirci","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Zeynep Kamil Women's and Children's Diseases Training and Research Hospital Istanbul 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Gynecology Zeynep Kamil Women's and Children's Diseases Training and Research Hospital Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,10,10]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e3181eeb80f"},{"key":"e_1_2_5_3_1","unstructured":"OS John IS Joseph MH Lisa LH Barbara DB Karen 2010 978\u20100\u201007\u2010147257\u20109 The Mcgraw\u2010Hill Companies Houston"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0029-7844(98)00218-X"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2004.03.003"},{"key":"e_1_2_5_6_1","first-page":"400","article-title":"Management of unruptured ectopic gestation by linear salpingostomy: A prospective, randomized trial of laparoscopy versus laparotomy","volume":"73","author":"Vermesh M","year":"1989","journal-title":"Obstet 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