{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T23:11:34Z","timestamp":1784157094862,"version":"3.55.0"},"reference-count":22,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2013,10,11]],"date-time":"2013-10-11T00:00:00Z","timestamp":1381449600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology of Japan","doi-asserted-by":"crossref","award":["19591946"],"award-info":[{"award-number":["19591946"]}],"id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2014,2]]},"abstract":"Abstract<\/jats:title>Aim<\/jats:title>This is the first report to determine the feasibility and safety of total laparoscopic modified radical hysterectomy (TLMRH<\/jats:styled-content>) in the treatment of presumed stage I<\/jats:styled-content> endometrial cancer.<\/jats:p><\/jats:sec>Methods<\/jats:title>This was a retrospective study of 132 consecutive patients who underwent surgery for early endometrial cancer. Thirty\u2010nine patients underwent TLMRH<\/jats:styled-content> and bilateral salpingo\u2010oophorectomy (BSO<\/jats:styled-content>), and 93 had a total abdominal extrafascial hysterectomy and BSO<\/jats:styled-content>. Lymphadenectomy was performed in 87 patients. The groups were compared for epidemiological and clinical characteristics, surgical outcomes, hospital stay, lymph nodes harvested, and intraoperative and postoperative complications.<\/jats:p><\/jats:sec>Results<\/jats:title>The patients in the TLMRH<\/jats:styled-content> group had less blood loss (42.9\u2009\u00b1\u200976.3 vs 236.8\u2009\u00b1\u2009186.6\u2009mL, P<\/jats:styled-content><\/jats:italic>\u2009<\u20090.0001), a similar number of lymph nodes removed (32.3\u2009\u00b1\u200913.1 vs 28.0\u2009\u00b1\u200911.9, P<\/jats:styled-content><\/jats:italic>\u2009=\u20090.15), less need for analgesia and a shorter hospital stay (9.3\u2009\u00b1\u20092.5 vs 14.6\u2009\u00b1\u200912.6 days, P<\/jats:styled-content><\/jats:italic>\u2009=\u20090.009) but longer operations (321.1\u2009\u00b1\u200965.9 vs 262.6\u2009\u00b1\u200975.0\u2009min, P<\/jats:styled-content><\/jats:italic>\u2009<\u20090.0001) than those treated by laparotomy. In our study, we had no conversions from laparoscopy to laparotomy. No major complications occurred in the TLMRH<\/jats:styled-content> group. The patients who underwent TLMRH<\/jats:styled-content> had less intense postoperative pain than patients treated by laparotomy. The median length of vaginal cuff removed was 12.0\u2009\u00b1\u20094.1\u2009mm in the TLMRH<\/jats:styled-content> group, and was 5.6\u2009\u00b1\u20096.6\u2009mm in the laparotomy group (P<\/jats:styled-content><\/jats:italic>\u2009<\u20090.0001). No patients demonstrated recurrence in either of the groups after a median follow\u2010up of 48.5\u2009months (range, 1\u201384).<\/jats:p><\/jats:sec>Conclusion<\/jats:title>TLMRH<\/jats:styled-content> is a safe and reliable alternative to open surgery in the management of early endometrial carcinoma, with a significantly reduced hospital stay and complications.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jog.12194","type":"journal-article","created":{"date-parts":[[2013,10,14]],"date-time":"2013-10-14T11:54:24Z","timestamp":1381751664000},"page":"570-575","source":"Crossref","is-referenced-by-count":23,"title":["Total laparoscopic modified radical hysterectomy with lymphadenectomy for endometrial cancer compared with laparotomy"],"prefix":"10.1111","volume":"40","author":[{"given":"Yoshito","family":"Terai","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Osaka Medical College Osaka 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Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saha","family":"Yoo","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Osaka Medical College Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshimichi","family":"Tanaka","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Osaka Medical College Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satoshi","family":"Tsunetoh","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Osaka Medical College Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masanori","family":"Kanemura","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Osaka Medical College Osaka 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