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Here we report a case of ovarian cancer with <jats:styled-content style=\"fixed-case\">LCNEC<\/jats:styled-content> which spread to distant organs within 1\u2009year of primary surgery despite the fact that the post\u2010surgical stage was Ia. The case received platinum\u2010based chemotherapy as an adjuvant therapy after her curative surgery. However, <jats:styled-content style=\"fixed-case\">LCNEC<\/jats:styled-content> in the case was resistant to the chemotherapy. In our review of published works, ovarian cancer cases with <jats:styled-content style=\"fixed-case\">LCNEC<\/jats:styled-content> show poor prognoses regardless of adjuvant chemotherapy following complete resection. Median overall survival was 10\u2009months in stage <jats:styled-content style=\"fixed-case\">I<\/jats:styled-content> cases. Development of chemotherapy sensitive for <jats:styled-content style=\"fixed-case\">LCNEC<\/jats:styled-content> is needed.<\/jats:p>","DOI":"10.1111\/jog.12235","type":"journal-article","created":{"date-parts":[[2013,11,26]],"date-time":"2013-11-26T05:52:47Z","timestamp":1385445167000},"page":"869-872","source":"Crossref","is-referenced-by-count":13,"title":["Poor prognosis of ovarian cancer with large cell neuroendocrine carcinoma: Case report and review of published works"],"prefix":"10.1111","volume":"40","author":[{"given":"Kayo","family":"Asada","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Faculty of Medicine The University of Tokyo  Tokyo Japan"},{"name":"Department of Obstetrics and Gynecology The Fraternity Memorial Hospital  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kei","family":"Kawana","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Faculty of Medicine The University of Tokyo  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shinichi","family":"Teshima","sequence":"additional","affiliation":[{"name":"Department of Pathology The Fraternity Memorial Hospital  Sumida\u2010ku Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ako","family":"Saito","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology The Fraternity Memorial Hospital  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masakiyo","family":"Kawabata","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology The Fraternity Memorial Hospital  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomoyuki","family":"Fujii","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Faculty of Medicine The University of Tokyo  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,11,26]]},"reference":[{"key":"e_1_2_5_2_1","first-page":"182","volume-title":"Pathology and Genetics of Tumours of the Breast and Female Genital Organs. 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