{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T14:53:00Z","timestamp":1787064780409,"version":"build-2736575974"},"reference-count":21,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2013,12,10]],"date-time":"2013-12-10T00:00:00Z","timestamp":1386633600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000870","name":"Macarthur Foundation","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100000870","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2014,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>\n                      The study investigated the effectiveness of sublingual misoprostol when used as primary treatment of primary post\u2010partum hemorrhage (\n                      <jats:styled-content style=\"fixed-case\">PPH<\/jats:styled-content>\n                      ) in a low\u2010income country.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Maternity care providers in three\n                      <jats:styled-content style=\"fixed-case\">N<\/jats:styled-content>\n                      igerian hospitals administrated 800\u2009\u03bcm sublingual misoprostol to women experiencing\n                      <jats:styled-content style=\"fixed-case\">PPH<\/jats:styled-content>\n                      . The outcome variables were estimated blood loss and the need for additional uterotonic drugs after initial treatment with misoprostol. Entry criteria included women in term spontaneous labor, while exclusion criteria were women with operative delivery and those experiencing\n                      <jats:styled-content style=\"fixed-case\">PPH<\/jats:styled-content>\n                      not due to atonic uterus.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      One hundred and thirty\u2010one women with\n                      <jats:styled-content style=\"fixed-case\">PPH<\/jats:styled-content>\n                      were treated over 6\u2009months. Estimated blood loss ranged 500\u20132500\u2009mL. Twenty women (15.3%) required additional uterotonic drugs to control continuing blood loss. There were no maternal deaths, while seven perinatal deaths were recorded.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      We conclude that although sublingual misoprostol is effective in reducing blood loss due to\n                      <jats:styled-content style=\"fixed-case\">PPH<\/jats:styled-content>\n                      , it does not effectively treat all forms of\n                      <jats:styled-content style=\"fixed-case\">PPH<\/jats:styled-content>\n                      . Additional uterotonics and other ancillary treatments would be required.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jog.12257","type":"journal-article","created":{"date-parts":[[2013,12,10]],"date-time":"2013-12-10T03:37:09Z","timestamp":1386646629000},"page":"718-722","source":"Crossref","is-referenced-by-count":7,"title":["Assessment of sublingual misoprostol as first\u2010line treatment for primary post\u2010partum hemorrhage: Results of a multicenter trial"],"prefix":"10.1111","volume":"40","author":[{"given":"Friday Ebhodaghe","family":"Okonofua","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology University of Benin  Benin City Rivers State Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosemary Nkemdilim","family":"Ogu","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology University of Port Harcourt  Port Harcourt Rivers State Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James Terkura","family":"Akuse","sequence":"additional","affiliation":[{"name":"Sefa Specialist Hospital  Kaduna Kaduna State Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Innocent Achaya Otobo","family":"Ujah","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology University of Jos  Jos Plateau State Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hadiza Shehu","family":"Galadanci","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Aminu Kano University Teaching Hospital  Kano Kano State Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adetokunbo Olusegun","family":"Fabamwo","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Lagos State University Teaching Hospital  Ikeja Lagos State Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,12,10]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(10)60518-1"},{"key":"e_1_2_7_3_1","first-page":"71","article-title":"Primary postpartum hemorrhage in a teaching hospital in Nigeria: A five year review","volume":"10","author":"Ajenfuja KO","year":"2010","journal-title":"Afr Health Sci"},{"key":"e_1_2_7_4_1","first-page":"55","article-title":"Maternal mortality and emergency obstetrics care in Benin City, South\u2010south Nigeria","volume":"2","author":"Aisien OA","year":"2010","journal-title":"J Clin Med Res"},{"key":"e_1_2_7_5_1","unstructured":"All Africa.144 daily maternal deaths in Nigeria. 30 March2010. 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