{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T18:01:13Z","timestamp":1789063273232,"version":"build-2803163510"},"reference-count":24,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2014,1,15]],"date-time":"2014-01-15T00:00:00Z","timestamp":1389744000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Ministry of Education, Science, and Culture of Japan","award":["19592487"],"award-info":[{"award-number":["19592487"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2014,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aims<\/jats:title><jats:p>Our objective was to evaluate the level of pregnant women's exposure to tobacco smoke by urinary cotinine testing at prenatal examinations, and to examine the effects of disclosing the results of urinary cotinine tests to pregnant women and their families on their smoking activities.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A prospective cohort study was conducted, enrolling 420 pregnant women who attended prenatal examinations at five private clinics in <jats:styled-content style=\"fixed-case\">J<\/jats:styled-content>apan. Urinary cotinine testing and a questionnaire survey regarding smoking status were conducted in early, middle, and late pregnancy. Urinary cotinine values were measured semiquantitatively using <jats:styled-content style=\"fixed-case\">NicCheck I<\/jats:styled-content> test strips. The results of each urinary cotinine test were handed to the pregnant woman and shared with her family.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The percentages of urinary cotinine\u2010positive subjects in middle and late pregnancy were significantly decreased compared with early pregnancy (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001 each). Among the active smokers, there were no significant differences in the urinary cotinine\u2010positive rates and the numbers of cigarettes among the three stages. In contrast, the urinary cotinine\u2010positive rates in the passive smokers in late pregnancy were significantly lower than in early pregnancy (<jats:italic>P<\/jats:italic>\u2009=\u20090.045) and those in non\u2010smokers in middle and late pregnancy were also lower than in early pregnancy (<jats:italic>P<\/jats:italic>\u2009=\u20090.001, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001). The numbers of cigarettes smoked by persons close to the passive smokers in middle and late pregnancy were significantly lower than in early pregnancy (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The feedback of the urinary cotinine test results at prenatal examinations decreased the level of exposure of pregnant passive smokers and non\u2010smokers to tobacco smoke.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jog.12285","type":"journal-article","created":{"date-parts":[[2014,1,15]],"date-time":"2014-01-15T21:53:29Z","timestamp":1389822809000},"page":"1015-1022","source":"Crossref","is-referenced-by-count":10,"title":["Reduction of tobacco smoke exposure for pregnant passive smokers using feedback of urinary cotinine test results"],"prefix":"10.1111","volume":"40","author":[{"given":"Yuka","family":"Higashida","sequence":"first","affiliation":[{"name":"Division of Health Sciences Osaka University Graduate School of Medicine  Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazutomo","family":"Ohashi","sequence":"additional","affiliation":[{"name":"Division of Health Sciences Osaka University Graduate School of Medicine  Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,1,15]]},"reference":[{"key":"e_1_2_7_2_1","unstructured":"Japan Tobacco Inc.JT's Annual Survey2010. [Cited 30 July 2013.] Available from URL:http:\/\/www.jt.com\/investors\/media\/press_releases\/2010\/0811_01\/index.html."},{"key":"e_1_2_7_3_1","unstructured":"The American Cancer Society and World Lung Foundation.The Tobacco Atlas Third Edition. [Cited 30 July2013.] Available from URL:http:\/\/www.tobaccoatlas.org\/downloads\/TobaccoAtlas_sm.pdf."},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ypmed.2007.04.009"},{"key":"e_1_2_7_5_1","unstructured":"World Health Organization.WHO Library Cataloguing\u2010in\u2010Publication Data: Protection from exposure to second\u2010hand tobacco smoke. Policy recommendations. 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