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Transvaginal ultrasound revealed an echo\u2010free space with mosaic echo pattern in the right adnexal area and no gestational sac in the uterus. With a preoperative diagnosis of ruptured ectopic pregnancy, emergency laparotomy was performed. The rectouterine pouch was filled with many clots containing small amounts of villous tissue. After removal of the conceptus, which was infiltrating into the peritoneum of the Pouch of Douglas, bleeding was controlled by Argon laser. Histological examination of the conceptus by immunohistochemical staining with p57<jats:sup>kip2<\/jats:sup> showed features of complete hydatidiform mole. This case demonstrates that the peritoneum in the <jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>ouch of<jats:styled-content style=\"fixed-case\"> D<\/jats:styled-content>ouglas is a possible site of ectopic complete hydatidiform mole occurrence and that immunohistochemical stain is useful to confirm the diagnosis of ectopic complete hydatidiform mole.<\/jats:p>","DOI":"10.1111\/jog.12287","type":"journal-article","created":{"date-parts":[[2014,1,15]],"date-time":"2014-01-15T21:53:47Z","timestamp":1389822827000},"page":"1154-1156","source":"Crossref","is-referenced-by-count":4,"title":["Rare case of peritoneal complete hydatidiform mole"],"prefix":"10.1111","volume":"40","author":[{"given":"Hajime","family":"Ota","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Hadano Red Cross Hospital  Kanagawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chikara","family":"Oda","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Hadano Red Cross Hospital  Kanagawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masaki","family":"Hayashi","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Hadano Red Cross Hospital  Kanagawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takao","family":"Mikoshiba","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Hadano Red Cross Hospital  Kanagawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miki","family":"Kushima","sequence":"additional","affiliation":[{"name":"Department of Pathology Showa University School of Medicine  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,1,15]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/deg008"},{"key":"e_1_2_6_3_1","first-page":"297","article-title":"Ectopic gestational trophoblastic disease: A case series review","volume":"57","author":"Hassadia A","year":"2012","journal-title":"J Reprod Med"},{"issue":"3","key":"e_1_2_6_4_1","first-page":"333","article-title":"Abdominal pregnancy in the United States: Frequency and maternal mortality","volume":"69","author":"Atrash HK","year":"1987","journal-title":"Obstet Gynecol"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2559.2001.01151.x"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.pgp.0000164597.19346.b5"},{"key":"e_1_2_6_7_1","first-page":"43","article-title":"Tubal hydatidiform mole: Report of a case","volume":"17","author":"Pour\u2010Reza M","year":"1974","journal-title":"Acta Med Iran"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(93)90168-I"},{"key":"e_1_2_6_9_1","first-page":"83","article-title":"On a case of primary abdominal molar pregnancy","volume":"4","author":"Dumitrescu P","year":"1960","journal-title":"Rum Med Rev"},{"key":"e_1_2_6_10_1","first-page":"329","article-title":"Hydatidiform mole in ectopic pregnancy: Clinical, imaging, pathological and immunohistochemical characteristics","volume":"57","author":"Cortes\u2010Charry R","year":"2012","journal-title":"J Reprod Med"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1048-891X.2004.014223.x"}],"container-title":["Journal of Obstetrics and Gynaecology Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjog.12287","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjog.12287","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jog.12287","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T06:26:35Z","timestamp":1759213595000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1111\/jog.12287"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,1,15]]},"references-count":10,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2014,4]]}},"alternative-id":["10.1111\/jog.12287"],"URL":"https:\/\/doi.org\/10.1111\/jog.12287","archive":["Portico"],"relation":{},"ISSN":["1341-8076","1447-0756"],"issn-type":[{"value":"1341-8076","type":"print"},{"value":"1447-0756","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,1,15]]}}}