{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T18:19:31Z","timestamp":1774635571175,"version":"3.50.1"},"reference-count":29,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2014,2,26]],"date-time":"2014-02-26T00:00:00Z","timestamp":1393372800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"KK Research Center"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2014,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To define the optimal gestational weight gain (<jats:styled-content style=\"fixed-case\">GWG<\/jats:styled-content>) for the multiethnic <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>ingaporean population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Data from 1529 live singleton deliveries was analyzed. A multinomial logistic regression analysis, with <jats:styled-content style=\"fixed-case\">GWG<\/jats:styled-content> as the predictor, was conducted to determine the lowest aggregated risk of a composite perinatal outcome, stratified by <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>sia\u2010specific body mass index (<jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content>) categories. The composite perinatal outcome, based on a combination of delivery type (cesarean section [<jats:styled-content style=\"fixed-case\">CS<\/jats:styled-content>], vaginal delivery [<jats:styled-content style=\"fixed-case\">VD<\/jats:styled-content>]) and size for gestational age (small [<jats:styled-content style=\"fixed-case\">SGA<\/jats:styled-content>], appropriate [<jats:styled-content style=\"fixed-case\">AGA<\/jats:styled-content>], large [<jats:styled-content style=\"fixed-case\">LGA<\/jats:styled-content>]), had six categories: (i) <jats:styled-content style=\"fixed-case\">VD<\/jats:styled-content> with <jats:styled-content style=\"fixed-case\">LGA<\/jats:styled-content>; (ii) <jats:styled-content style=\"fixed-case\">VD<\/jats:styled-content> with <jats:styled-content style=\"fixed-case\">SGA<\/jats:styled-content>; (iii) <jats:styled-content style=\"fixed-case\">CS<\/jats:styled-content> with <jats:styled-content style=\"fixed-case\">AGA<\/jats:styled-content>; (iv) <jats:styled-content style=\"fixed-case\">CS<\/jats:styled-content> with <jats:styled-content style=\"fixed-case\">SGA<\/jats:styled-content>; (v) <jats:styled-content style=\"fixed-case\">CS<\/jats:styled-content> with <jats:styled-content style=\"fixed-case\">LGA<\/jats:styled-content>; (vi) and <jats:styled-content style=\"fixed-case\">VD<\/jats:styled-content> with <jats:styled-content style=\"fixed-case\">AGA<\/jats:styled-content>. The last was considered as the \u2018normal\u2019 reference category. In each <jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content> category, the <jats:styled-content style=\"fixed-case\">GWG<\/jats:styled-content> value corresponding to the lowest aggregated risk was defined as the optimal <jats:styled-content style=\"fixed-case\">GWG<\/jats:styled-content>, and the <jats:styled-content style=\"fixed-case\">GWG<\/jats:styled-content> values at which the aggregated risk did not exceed a 5% increase from the lowest aggregated risk were defined as the margins of the optimal <jats:styled-content style=\"fixed-case\">GWG<\/jats:styled-content> range.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The optimal <jats:styled-content style=\"fixed-case\">GWG<\/jats:styled-content> by pre\u2010pregnancy <jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content> category, was 19.5\u2009kg (range, 12.9 to 23.9) for underweight, 13.7\u2009kg (7.7 to 18.8) for normal weight, 7.9\u2009kg (2.6 to 14.0) for overweight and 1.8\u2009kg (\u22125.0 to 7.0) for obese.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The results of this study, the first to determine optimal <jats:styled-content style=\"fixed-case\">GWG<\/jats:styled-content> in the multiethnic Singaporean population, concur with the Institute of Medicine (<jats:styled-content style=\"fixed-case\">IOM<\/jats:styled-content>) guidelines in that <jats:styled-content style=\"fixed-case\">GWG<\/jats:styled-content> among Asian women who are heavier prior to pregnancy, especially those who are obese, should be lower. However, the optimal <jats:styled-content style=\"fixed-case\">GWG<\/jats:styled-content> for underweight and obese women was outside the <jats:styled-content style=\"fixed-case\">IOM<\/jats:styled-content> recommended range.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jog.12307","type":"journal-article","created":{"date-parts":[[2014,2,26]],"date-time":"2014-02-26T02:30:56Z","timestamp":1393381856000},"page":"1002-1008","source":"Crossref","is-referenced-by-count":42,"title":["Determining optimal gestational weight gain in a multiethnic <scp>A<\/scp>sian population"],"prefix":"10.1111","volume":"40","author":[{"given":"Tat Xin","family":"Ee","sequence":"first","affiliation":[{"name":"Duke\u2010NUS Graduate Medical School  Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"Jr","given":"John Carson","family":"Allen","sequence":"additional","affiliation":[{"name":"Office of Clinical Sciences Duke\u2010NUS Graduate Medical School  Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rahul","family":"Malhotra","sequence":"additional","affiliation":[{"name":"Health Services and Systems Research Duke\u2010NUS Graduate Medical School  Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huishan","family":"Koh","sequence":"additional","affiliation":[{"name":"Duke\u2010NUS Graduate Medical School  Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Truls","family":"\u00d8stbye","sequence":"additional","affiliation":[{"name":"Duke\u2010NUS Graduate Medical School  Singapore"},{"name":"Duke Global Health Institute  Durham North Carolina USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thiam Chye","family":"Tan","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynaecology KK Women's and Children's Hospital  Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,2,26]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e31818b5dd9"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10995-008-0318-4"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2007.01483.x"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000242568.75785.68"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10995-011-0741-9"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.2009.27919"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/0029-7844(95)00119-C"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1701-2163(16)34432-2"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000278819.17190.87"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajhb.10139"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.2009.29008"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1467-789X.2011.00886.x"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7827-9-6"},{"key":"e_1_2_6_15_1","volume-title":"Subcommittee on Nutritional Status and Weight Gain during Pregnancy., Institute of Medicine (U.S.). 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