{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T15:53:47Z","timestamp":1759334027074,"version":"build-2065373602"},"reference-count":30,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2014,3,10]],"date-time":"2014-03-10T00:00:00Z","timestamp":1394409600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2014,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>Even though polycystic ovary syndrome (<jats:styled-content style=\"fixed-case\">PCOS<\/jats:styled-content>) is characterized by increased inflammatory activity and insulin resistance, there is no clinical data about whether risk of atrial fibrillation are increased in these patients. We aimed to evaluate atrial conduction parameters predicting atrial involvement in this patient group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The study population comprised 50 women 18\u201340 years of age who had been diagnosed with <jats:styled-content style=\"fixed-case\">PCOS<\/jats:styled-content>. The patients were divided into two groups: lean women (<jats:styled-content style=\"fixed-case\">L<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">PCOS<\/jats:styled-content>) with a body mass index (<jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content>) under 25\u2009kg\/m<jats:sup>2<\/jats:sup> and obese women (<jats:styled-content style=\"fixed-case\">O<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">PCOS<\/jats:styled-content>) with a <jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content> greater than 30\u2009kg\/m<jats:sup>2<\/jats:sup>. Twenty\u2010five age\u2010matched lean healthy women were enrolled voluntarily as the control group. Difference between maximum and minimum <jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>\u2010wave duration was calculated and was defined as <jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>\u2010wave dispersion (<jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>d). Inter\u2010 and intra\u2010atrial electromechanical delays (inter\u2010<jats:styled-content style=\"fixed-case\">AED<\/jats:styled-content>, intra\u2010<jats:styled-content style=\"fixed-case\">AED<\/jats:styled-content>, respectively) were measured with tissue Doppler imaging.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Inter\u2010 and intra\u2010<jats:styled-content style=\"fixed-case\">AED<\/jats:styled-content> parameters were higher in the <jats:styled-content style=\"fixed-case\">L<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">PCOS<\/jats:styled-content> group when compared with control subjects (<jats:sc>anova<\/jats:sc>, <jats:italic>P<\/jats:italic>\u2009=\u20090.004 and <jats:italic>P<\/jats:italic>\u2009=\u20090.013, respectively), and were also significantly higher in the <jats:styled-content style=\"fixed-case\">O<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">PCOS<\/jats:styled-content> group compared with other groups (<jats:sc>anova<\/jats:sc>, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001 for both). The regression analyses indicated that <jats:styled-content style=\"fixed-case\">H<\/jats:styled-content>omeostasis <jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>odel of <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>ssessment \u2013 <jats:styled-content style=\"fixed-case\">I<\/jats:styled-content>nsulin <jats:styled-content style=\"fixed-case\">R<\/jats:styled-content>esistance (<jats:styled-content style=\"fixed-case\">HOMA\u2010IR<\/jats:styled-content>) (\u03b2\u2009=\u20090.603, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001) and <jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content> (\u03b2\u2009=\u20090.379, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001) were the independent predictors of inter\u2010<jats:styled-content style=\"fixed-case\">AED<\/jats:styled-content>, <jats:styled-content style=\"fixed-case\">HOMA\u2010IR<\/jats:styled-content> (\u03b2\u2009=\u20090.835, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001) was an independent predictor of intra\u2010<jats:styled-content style=\"fixed-case\">AED<\/jats:styled-content>, and <jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content> (\u03b2\u2009=\u20090.457, <jats:italic>P<\/jats:italic>\u2009=\u20090.006) and the left atrial diameter (\u03b2\u2009=\u20090.350, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.034) were independent predictors of <jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>d.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Consequently, our findings provide data regarding prolonged atrial conduction parameters in <jats:styled-content style=\"fixed-case\">PCOS<\/jats:styled-content> patients, especially when accompanied by obesity.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jog.12308","type":"journal-article","created":{"date-parts":[[2014,3,10]],"date-time":"2014-03-10T05:20:40Z","timestamp":1394428840000},"page":"1059-1066","source":"Crossref","is-referenced-by-count":5,"title":["Assessment of atrial electromechanical delay in patients with polycystic ovary syndrome in both lean and obese subjects"],"prefix":"10.1111","volume":"40","author":[{"given":"Hakan","family":"Ta\u015folar","sequence":"first","affiliation":[{"name":"Training and Research Hospital Department of Cardiology Adiyaman University  Adiyaman Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T\u00fcrkan","family":"Mete","sequence":"additional","affiliation":[{"name":"Training and Research Hospital Department of Endocrinology and Metabolism Adiyaman University  Adiyaman Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mehmet","family":"Ball\u0131","sequence":"additional","affiliation":[{"name":"Training and Research Hospital Department of Cardiology Adiyaman University  Adiyaman Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Burak","family":"Altun","sequence":"additional","affiliation":[{"name":"Department of Cardiology 18 Mart University, Faculty of Medicine  \u00c7anakkale Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mustafa","family":"\u00c7etin","sequence":"additional","affiliation":[{"name":"Training and Research Hospital Department of Cardiology Adiyaman University  Adiyaman Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tuncay","family":"Y\u00fcce","sequence":"additional","affiliation":[{"name":"Training and Research Hospital Department of Obstetrics and Gynecology Adiyaman University  Adiyaman Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sevgi","family":"Ta\u015folar","sequence":"additional","affiliation":[{"name":"Training and Research Hospital Department of Radiology Adiyaman University  Adiyaman Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00d6m\u00fcr","family":"Otlu","sequence":"additional","affiliation":[{"name":"Department of Cardiology Inonu University, Faculty of Medicine  Malatya Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adil","family":"Bayramo\u011flu","sequence":"additional","affiliation":[{"name":"Department of Cardiology Inonu University, Faculty of Medicine  Malatya Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hasan","family":"Pekdemir","sequence":"additional","affiliation":[{"name":"Department of Cardiology Inonu University, Faculty of Medicine  Malatya Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,3,10]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2003.10.004"},{"key":"e_1_2_5_3_1","first-page":"447","article-title":"Evaluation of atrial electromechanical delay and left atrial mechanical functions in patients with rheumatoid arthritis","volume":"37","author":"Acar G","year":"2009","journal-title":"Turk Kardiyol Dern Ars"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2265.1995.tb00534.x"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.103.10.1410"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1210\/jcem.86.6.7580"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1210\/er.18.6.774"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1985.03360240061035"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2006.04.026"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8159.2004.00473.x"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/oby.2010.195"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jelectrocard.2010.02.013"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(15)30642-6"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.102.1.42"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0026-0495(99)90100-2"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1210\/jcem-50-1-113"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.2337\/diab.38.9.1165"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2003-032049"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dms030"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10840-011-9658-x"},{"key":"e_1_2_5_21_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejechocard\/jer227"},{"key":"e_1_2_5_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8175.2008.00838.x"},{"key":"e_1_2_5_23_1","doi-asserted-by":"publisher","DOI":"10.1038\/oby.2002.104"},{"key":"e_1_2_5_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2004.08.029"},{"key":"e_1_2_5_25_1","first-page":"525","article-title":"Evaluation of atrial conduction time by P wave dispersion and tissue Doppler echocardiography in prehypertensive patients","volume":"38","author":"Ermi\u015f N","year":"2010","journal-title":"Turk Kardiyol Dern Ars"},{"key":"e_1_2_5_26_1","doi-asserted-by":"publisher","DOI":"10.1038\/ajh.2009.231"},{"key":"e_1_2_5_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8159.2009.02460.x"},{"key":"e_1_2_5_28_1","doi-asserted-by":"publisher","DOI":"10.1253\/circj.71.880"},{"key":"e_1_2_5_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8159.1999.tb00358.x"},{"key":"e_1_2_5_30_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.84.1.165"},{"key":"e_1_2_5_31_1","doi-asserted-by":"publisher","DOI":"10.2337\/diabetes.47.10.1643"}],"container-title":["Journal of Obstetrics and Gynaecology Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjog.12308","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjog.12308","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jog.12308","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T06:26:41Z","timestamp":1759213601000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1111\/jog.12308"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,3,10]]},"references-count":30,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2014,4]]}},"alternative-id":["10.1111\/jog.12308"],"URL":"https:\/\/doi.org\/10.1111\/jog.12308","archive":["Portico"],"relation":{},"ISSN":["1341-8076","1447-0756"],"issn-type":[{"type":"print","value":"1341-8076"},{"type":"electronic","value":"1447-0756"}],"subject":[],"published":{"date-parts":[[2014,3,10]]}}}