{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T19:39:11Z","timestamp":1789587551949,"version":"build-2803163510"},"reference-count":29,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2014,8,11]],"date-time":"2014-08-11T00:00:00Z","timestamp":1407715200000},"content-version":"vor","delay-in-days":10,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2014,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>The aim of this study was to evaluate the advantages of laparoscopic cornuotomy in treating interstitial pregnancy, and the effect of the procedure on reproductive outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Thirteen patients were treated for interstitial pregnancy by laparoscopic cornuotomy with or without local methotrexate injection, between <jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>arch 2000 and <jats:styled-content style=\"fixed-case\">J<\/jats:styled-content>anuary 2012 at <jats:styled-content style=\"fixed-case\">NTT E<\/jats:styled-content>ast <jats:styled-content style=\"fixed-case\">J<\/jats:styled-content>apan <jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>ohoku <jats:styled-content style=\"fixed-case\">H<\/jats:styled-content>ospital and <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>endai <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>ity <jats:styled-content style=\"fixed-case\">H<\/jats:styled-content>ospital. The patients were followed to assess the outcomes of subsequent pregnancies for at least 1\u2009year after the operation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>All 13 cases of interstitial pregnancy were successfully treated by laparoscopic cornuotomy, without performing cornual resection or laparotomy. The mean gestational age was 7.6\u2009\u00b1\u20091.3\u2009weeks, and the average serum <jats:styled-content style=\"fixed-case\">hCG<\/jats:styled-content> level was 20\u2009800\u2009\u00b1\u200918\u2009100\u2009IU\/L. The mean cornual mass size was 34.6\u2009\u00b1\u200910.2\u2009mm. Eight of the patients later obtained a spontaneous intrauterine pregnancy. Three patients that delivered by cesarean section showed no uterine dehiscence or thinning of the scar at the site of the earlier cornual incision and repair. None of the patients experienced uterine rupture.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Interstitial pregnancy can be selectively treated by laparoscopic cornuotomy with local methotrexate injection, if managed carefully.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jog.12422","type":"journal-article","created":{"date-parts":[[2015,1,30]],"date-time":"2015-01-30T01:20:40Z","timestamp":1422580840000},"page":"1983-1988","source":"Crossref","is-referenced-by-count":25,"title":["Laparoscopic cornuotomy for interstitial pregnancy and postoperative course"],"prefix":"10.1111","volume":"40","author":[{"given":"Tadashi","family":"Watanabe","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology NTT East Japan Tohoku Hospital  Sendai Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zen","family":"Watanabe","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology NTT East Japan Tohoku Hospital  Sendai Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takanori","family":"Watanabe","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Sendai City Hospital  Sendai Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kumiko","family":"Fujimoto","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Saka General Hospital  Tagajo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Etsuko","family":"Sasaki","sequence":"additional","affiliation":[{"name":"Etsuko Sasaki Clinic of Obstetrics and Gynecology  Sendai Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,8,11]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(99)00242-3"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000109218.24211.79"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(16)46349-1"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/0029-7844(94)00423-B"},{"key":"e_1_2_7_6_1","first-page":"569","article-title":"Successful treatment of ruptured interstitial pregnancy with laparoscopic surgery. 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