{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,27]],"date-time":"2026-04-27T11:48:40Z","timestamp":1777290520061,"version":"3.51.4"},"reference-count":20,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2014,7,23]],"date-time":"2014-07-23T00:00:00Z","timestamp":1406073600000},"content-version":"vor","delay-in-days":22,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2014,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To assess the use of magnetic resonance imaging (<jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content>) for prenatal differentiation between complete hydatidiform mole with a twin live fetus (<jats:styled-content style=\"fixed-case\">CHMTF<\/jats:styled-content>) and placental mesenchymal dysplasia (<jats:styled-content style=\"fixed-case\">PMD<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Three <jats:styled-content style=\"fixed-case\">CHMTF<\/jats:styled-content> cases and three <jats:styled-content style=\"fixed-case\">PMD<\/jats:styled-content> cases, from two institutions over a 6\u2010year period, were retrospectively included in this study. Clinical findings including age, pregnancy history, serum h<jats:styled-content style=\"fixed-case\">CG<\/jats:styled-content> level, ultrasonography findings, complications of the mother, outcome of the fetus, and results of chromosomal study of fetus, amniotic fluid and lesion, if possible, were noted. <jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content> findings were evaluated by two radiologists with respect to the location of the disease (intra\u2010 or extra\u2010fetal sac), the presence of multicystic component, and presence of intra\u2010 or extra\u2010lesional hemorrhage.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In all six cases, the diseases were recognized as multicystic lesions by ultrasonography and <jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content>. In two of three <jats:styled-content style=\"fixed-case\">CHMTF<\/jats:styled-content> cases, patients continued with the pregnancy, which resulted in spontaneous abortion. In one case of <jats:styled-content style=\"fixed-case\">CHMTF<\/jats:styled-content>, the patient underwent artificial abortion, after which the mole progressed into an invasive mole with lung metastases. All three <jats:styled-content style=\"fixed-case\">PMD<\/jats:styled-content> patients had live births, and two of the three babies had fetal growth restriction. By <jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content>, <jats:styled-content style=\"fixed-case\">CHMTF<\/jats:styled-content> was located within an extra\u2010fetal sac accompanied by intra\u2010 and\/or extra\u2010lesional hemorrhage, while <jats:styled-content style=\"fixed-case\">PMD<\/jats:styled-content> was located within the placenta in the fetal sac without hemorrhage.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content> could provide important information about the prenatal differential diagnosis of <jats:styled-content style=\"fixed-case\">CHMTF<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">PMD<\/jats:styled-content>, based on the pathophysiology and characteristics of the diseases.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jog.12441","type":"journal-article","created":{"date-parts":[[2014,7,23]],"date-time":"2014-07-23T14:25:19Z","timestamp":1406125519000},"page":"1894-1900","source":"Crossref","is-referenced-by-count":36,"title":["Prenatal differential diagnosis of complete hydatidiform mole with a twin live fetus and placental mesenchymal dysplasia by magnetic resonance imaging"],"prefix":"10.1111","volume":"40","author":[{"given":"Yuki","family":"Himoto","sequence":"first","affiliation":[{"name":"Department of Diagnostic Imaging and Nuclear Medicine Graduate School of Medicine Kyoto University  Kyoto Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aki","family":"Kido","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Imaging and Nuclear Medicine Graduate School of Medicine Kyoto University  Kyoto Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sachiko","family":"Minamiguchi","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Pathology Graduate School of Medicine Kyoto University  Kyoto Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yusaku","family":"Moribata","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Imaging and Nuclear Medicine Graduate School of Medicine Kyoto University  Kyoto Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryosuke","family":"Okumura","sequence":"additional","affiliation":[{"name":"Department of Radiology Kitano Hospital  Osaka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haruta","family":"Mogami","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics Graduate School of Medicine Kyoto University  Kyoto Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tadayoshi","family":"Nagano","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Kitano Hospital  Osaka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ikuo","family":"Konishi","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics Graduate School of Medicine Kyoto University  Kyoto Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kaori","family":"Togashi","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Imaging and Nuclear Medicine Graduate School of Medicine Kyoto University  Kyoto Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,7,23]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.12359"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1159\/000350661"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00404-008-0812-3"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2011.08.019"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2008.12.006"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/15.3.608"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(97)70546-5"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(02)09085-2"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1309\/RV45HRD53YQ2YFTP"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e3182161828"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1148\/rg.295085242"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.rct.0000162408.17042.3d"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.07.7104"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00795-007-0362-y"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.7863\/jum.2009.28.3.359"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1148\/rg.241035027"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.172.2.9930801"},{"key":"e_1_2_7_19_1","first-page":"1353","volume-title":"Novak's Gynecology","author":"Berkowitz RS","year":"2002"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1440-1827.2003.01550.x"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.11.7405"}],"container-title":["Journal of Obstetrics and Gynaecology Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjog.12441","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjog.12441","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jog.12441","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,2]],"date-time":"2023-10-02T20:04:39Z","timestamp":1696277079000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1111\/jog.12441"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,7]]},"references-count":20,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2014,7]]}},"alternative-id":["10.1111\/jog.12441"],"URL":"https:\/\/doi.org\/10.1111\/jog.12441","archive":["Portico"],"relation":{},"ISSN":["1341-8076","1447-0756"],"issn-type":[{"value":"1341-8076","type":"print"},{"value":"1447-0756","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,7]]}}}