{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,12,21]],"date-time":"2023-12-21T17:20:01Z","timestamp":1703179201210},"reference-count":33,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2014,7,23]],"date-time":"2014-07-23T00:00:00Z","timestamp":1406073600000},"content-version":"vor","delay-in-days":22,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2014,7]]},"abstract":"Abstract<\/jats:title>Aim<\/jats:title>To review and evaluate the efficacy of kidney\u2010tonifying traditional C<\/jats:styled-content>hinese medicine prescriptions (KT<\/jats:styled-content>\u2010TCMP<\/jats:styled-content>) in hypoplastic uterus (HU<\/jats:styled-content>) treatment.<\/jats:p><\/jats:sec>Methods<\/jats:title>We searched MEDLINE<\/jats:styled-content>, the C<\/jats:styled-content>ochrane L<\/jats:styled-content>ibrary, CNKI<\/jats:styled-content> (C<\/jats:styled-content>hina N<\/jats:styled-content>ational K<\/jats:styled-content>nowledge I<\/jats:styled-content>nfrastructure), WANFANG<\/jats:styled-content> and VIP<\/jats:styled-content> databases until 14\u2009D<\/jats:styled-content>ecember 2013 independently with two investigators. Randomized controlled trials (RCT<\/jats:styled-content>) involving KT<\/jats:styled-content>\u2010TCMP<\/jats:styled-content> as a combined or monotherapy in the treatment of HU<\/jats:styled-content> were reviewed and analyzed. Meta\u2010analysis was performed by R<\/jats:styled-content>eview M<\/jats:styled-content>anager (version 5.2).<\/jats:p><\/jats:sec>Results<\/jats:title>Nine RCT<\/jats:styled-content> of 1745 patients were eligible for this review and meta\u2010analysis, of which eight RCT<\/jats:styled-content> described the primary outcome of clinical efficacy and three RCT<\/jats:styled-content> drew the secondary outcome of uterine size. Meta\u2010analyzed \u2018recovery\u2019 clinical efficacy of KT<\/jats:styled-content>\u2010TCMP<\/jats:styled-content> in seven RCT<\/jats:styled-content> was conducted which considered diethylstilbestrol therapy alone as control, as well as three RCT<\/jats:styled-content> that meta\u2010analyzed the effect of KT<\/jats:styled-content>\u2010TCMP<\/jats:styled-content> on uterine diameter enlargement. As a result, KT<\/jats:styled-content>\u2010TCMP<\/jats:styled-content> therapy had a significantly improved difference in increasing \u2018recovery\u2019 clinical efficacy (risk ratio, 2.34; 95% confidence interval [CI<\/jats:styled-content>], 1.90\u20132.89) and enlarging the uterine diameter (standardized mean difference, 1.62; 95% CI<\/jats:styled-content>, 1.39\u20131.84). One study reported adverse reactions as an important outcome and found it was safe during KT<\/jats:styled-content>\u2010TCMP<\/jats:styled-content> therapy.<\/jats:p><\/jats:sec>Conclusion<\/jats:title>The therapy of applying KT<\/jats:styled-content>\u2010TCMP<\/jats:styled-content> as a combined or monotherapy in the treatment of HU<\/jats:styled-content> may be more efficacious. However, these RCT<\/jats:styled-content> were of moderate methodological quality and small sample size; thus, the results should be confirmed with more rigorously controlled further studies.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jog.12451","type":"journal-article","created":{"date-parts":[[2014,7,23]],"date-time":"2014-07-23T14:25:19Z","timestamp":1406125519000},"page":"1913-1924","source":"Crossref","is-referenced-by-count":1,"title":["Efficacy of kidney\u2010tonifying traditional C<\/scp>hinese medicine prescriptions in hypoplastic uterus treatment: A systematic review and meta\u2010analysis"],"prefix":"10.1111","volume":"40","author":[{"given":"Xichuang","family":"Chen","sequence":"first","affiliation":[{"name":"Department of Pharmacy Affiliated Wuxi No. 9 People's Hospital, Soochow University and Wuxi Hand Surgery Hospital Wuxi China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuan","family":"Hong","sequence":"additional","affiliation":[{"name":"Department of 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9 People's Hospital, Soochow University and Wuxi Hand Surgery Hospital Wuxi China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jianlin","family":"Ye","sequence":"additional","affiliation":[{"name":"Department of Pharmacy Ningbo No. 6 Hospital Ningbo China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huizhu","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Pharmacy Ningbo No. 6 Hospital Ningbo China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaohong","family":"You","sequence":"additional","affiliation":[{"name":"Department of Pharmacy Affiliated Wuxi No. 9 People's Hospital, Soochow University and Wuxi Hand Surgery Hospital Wuxi 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