{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T02:06:03Z","timestamp":1793325963014,"version":"4.5.0"},"reference-count":30,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2014,8,28]],"date-time":"2014-08-28T00:00:00Z","timestamp":1409184000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2015,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>Massive obstetric hemorrhage (<jats:styled-content style=\"fixed-case\">MOH<\/jats:styled-content>) requires prompt transfusion of red blood cells and coagulation factors. Because <jats:styled-content style=\"fixed-case\">MOH<\/jats:styled-content> has a diverse pathogenesis, the shock index (<jats:styled-content style=\"fixed-case\">SI<\/jats:styled-content>) alone may be insufficient for determining blood transfusion. Here, we retrospectively analyzed patients with <jats:styled-content style=\"fixed-case\">MOH<\/jats:styled-content> to determine usefulness of the indicators of shock including the <jats:styled-content style=\"fixed-case\">SI<\/jats:styled-content> in evaluating the need for blood transfusion.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We reviewed records of 80 emergency referral patients who had received blood transfusions at our department between 1\u2009<jats:styled-content style=\"fixed-case\">J<\/jats:styled-content>anuary 2009 and 31\u2009<jats:styled-content style=\"fixed-case\">J<\/jats:styled-content>uly 2011. The shock indicators for blood transfusion are estimated blood loss, fibrinogen level, hemoglobin concentration, the <jats:styled-content style=\"fixed-case\">J<\/jats:styled-content>apan <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>ociety of <jats:styled-content style=\"fixed-case\">O<\/jats:styled-content>bstetrics and <jats:styled-content style=\"fixed-case\">G<\/jats:styled-content>ynecology disseminated intravascular coagulation (<jats:styled-content style=\"fixed-case\">JSOG DIC<\/jats:styled-content>) score and the <jats:styled-content style=\"fixed-case\">SI<\/jats:styled-content>. The strength of the correlation of each shock indicator with the transfusion volume was ranked using Spearman's rank correlation coefficient\u2010\u03c1 and multivariate analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Although the <jats:styled-content style=\"fixed-case\">SI<\/jats:styled-content> showed significant positive correlation with blood transfusion volume for red blood cell concentrate (<jats:styled-content style=\"fixed-case\">RCC<\/jats:styled-content>) and fresh frozen plasma (<jats:styled-content style=\"fixed-case\">FFP<\/jats:styled-content>) in patients with dilutional coagulopathy, a stronger correlation was seen with the fibrinogen level and <jats:styled-content style=\"fixed-case\">JSOG DIC<\/jats:styled-content> score. In patients with consumptive coagulopathy, the strongest correlation was seen between <jats:styled-content style=\"fixed-case\">RCC<\/jats:styled-content> transfusion volume and fibrinogen level, and between <jats:styled-content style=\"fixed-case\">FFP<\/jats:styled-content> transfusion volume and <jats:styled-content style=\"fixed-case\">JSOG DIC<\/jats:styled-content> score followed by fibrinogen level. In multivariate analysis, only fibrinogen level was significantly associated with both <jats:styled-content style=\"fixed-case\">RCC<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">FFP<\/jats:styled-content> massive transfusion.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Because <jats:styled-content style=\"fixed-case\">MOH<\/jats:styled-content> has a diverse pathogenesis, various indicators should be evaluated. Among shock indicators, fibrinogen level was the best indicator of the need for blood transfusion following <jats:styled-content style=\"fixed-case\">MOH<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jog.12480","type":"journal-article","created":{"date-parts":[[2014,8,28]],"date-time":"2014-08-28T05:43:07Z","timestamp":1409204587000},"page":"39-43","source":"Crossref","is-referenced-by-count":38,"title":["Usefulness of shock indicators for determining the need for blood transfusion after massive obstetric hemorrhage"],"prefix":"10.1111","volume":"41","author":[{"given":"Sumiko","family":"Era","sequence":"first","affiliation":[{"name":"Center for Maternal, Fetal and Neonatal Medicine Saitama Medical Center Saitama Medical University  Kawagoe Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shigetaka","family":"Matsunaga","sequence":"additional","affiliation":[{"name":"Center for Maternal, Fetal and Neonatal Medicine Saitama Medical Center Saitama Medical University  Kawagoe Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideyoshi","family":"Matsumura","sequence":"additional","affiliation":[{"name":"Center for Maternal, Fetal and Neonatal Medicine Saitama Medical Center Saitama Medical University  Kawagoe Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshihiko","family":"Murayama","sequence":"additional","affiliation":[{"name":"Center for Maternal, Fetal and Neonatal Medicine Saitama Medical Center Saitama Medical University  Kawagoe Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasushi","family":"Takai","sequence":"additional","affiliation":[{"name":"Center for Maternal, Fetal and Neonatal Medicine Saitama Medical Center Saitama Medical University  Kawagoe Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroyuki","family":"Seki","sequence":"additional","affiliation":[{"name":"Center for Maternal, Fetal and Neonatal Medicine Saitama Medical Center Saitama Medical University  Kawagoe Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,8,28]]},"reference":[{"key":"e_1_2_7_2_1","unstructured":"Postpartum hemorrhage. 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