{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T19:59:38Z","timestamp":1781812778340,"version":"3.54.5"},"reference-count":12,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2014,10,20]],"date-time":"2014-10-20T00:00:00Z","timestamp":1413763200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2015,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Diffuse uterine leiomyomatosis (<jats:styled-content style=\"fixed-case\">DUL<\/jats:styled-content>) is a rare clinical entity with important reproductive consequences. To date, only four pregnancies have been reported after hysteroscopic myomectomy. Here we describe the case of a 28\u2010year\u2010old infertile woman with diffuse uterine leiomyomatosis, who presented infertility and metrorrhagia lasting for 2 years. A countless number of subserous, intramural and submucous myomas were ultrasonographically revealed. Diagnostic hysteroscopy described a uterine cavity completely subverted by the presence of myomas. A two\u2010step \u2018cold loop\u2019 hysteroscopic myomectomy was performed following the technique previously described. One month after the treatment, there were no submucous myomas. A regular uterine cavity free of synechiae was endoscopically confirmed. After the treatment, the patient carried to term three consecutive, uneventful pregnancies. This is the first report of repeated successful pregnancies following the \u2018cold loop\u2019 hysteroscopic technique in <jats:styled-content style=\"fixed-case\">DUL<\/jats:styled-content>. We believe that \u2018cold loop\u2019 resectoscopic myomectomy may provide new advantageous perspectives for women with <jats:styled-content style=\"fixed-case\">DUL<\/jats:styled-content> seeking pregnancy.<\/jats:p>","DOI":"10.1111\/jog.12548","type":"journal-article","created":{"date-parts":[[2014,10,21]],"date-time":"2014-10-21T00:43:39Z","timestamp":1413852219000},"page":"474-477","source":"Crossref","is-referenced-by-count":22,"title":["Is \u2018cold loop\u2019 hysteroscopic myomectomy a better option for reproduction in women with diffuse uterine leiomyomatosis? A case report of successful repeated pregnancies"],"prefix":"10.1111","volume":"41","author":[{"given":"Ivano","family":"Mazzon","sequence":"first","affiliation":[{"name":"\u2018Arbor Vitae\u2019 Centre Clinica Nuova Villa Claudia  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandro","family":"Favilli","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology University of Perugia  Perugia Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mario","family":"Grasso","sequence":"additional","affiliation":[{"name":"\u2018Arbor Vitae\u2019 Centre Clinica Nuova Villa Claudia  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela","family":"Morricone","sequence":"additional","affiliation":[{"name":"\u2018Arbor Vitae\u2019 Centre Clinica Nuova Villa Claudia  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gian Carlo","family":"Di Renzo","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology University of Perugia  Perugia Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandro","family":"Gerli","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology University of Perugia  Perugia Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,10,20]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004347-198712000-00004"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0046-8177(00)80016-7"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2007.01.100"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00404-008-0864-4"},{"key":"e_1_2_5_6_1","first-page":"82S","article-title":"Diffuse leiomyomatosis of the uterus precluding myomectomy","volume":"53","author":"Lapan B","year":"1979","journal-title":"Obstet Gynecol"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2011.05.077"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dmm041"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2013.09.032"},{"key":"e_1_2_5_10_1","first-page":"736","article-title":"Transcervical hysteroscopic resection of submucous fibroids for abnormal uterine bleeding: Results regarding the degree of intramural extension","volume":"82","author":"Wamsteker K","year":"1993","journal-title":"Obstet Gynecol"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2004.01.029"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2011.04.004"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmig.2010.04.015"}],"container-title":["Journal of Obstetrics and Gynaecology Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjog.12548","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjog.12548","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jog.12548","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T07:30:13Z","timestamp":1695540613000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1111\/jog.12548"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,10,20]]},"references-count":12,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2015,3]]}},"alternative-id":["10.1111\/jog.12548"],"URL":"https:\/\/doi.org\/10.1111\/jog.12548","archive":["Portico"],"relation":{},"ISSN":["1341-8076","1447-0756"],"issn-type":[{"value":"1341-8076","type":"print"},{"value":"1447-0756","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,10,20]]}}}