{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T15:15:03Z","timestamp":1759936503413},"reference-count":15,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2014,10,10]],"date-time":"2014-10-10T00:00:00Z","timestamp":1412899200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2015,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The autoimmune lymphoproliferative syndrome (<jats:styled-content style=\"fixed-case\">ALPS<\/jats:styled-content>) is a disorder of abnormal lymphocyte survival caused by the dysregulation of the <jats:styled-content style=\"fixed-case\">F<\/jats:styled-content>as apoptotic pathway. The <jats:styled-content style=\"fixed-case\">F<\/jats:styled-content>as gene is expressed at the maternal\u2013fetal interface and is involved in the regulation of immune response and implantation. Altered <jats:styled-content style=\"fixed-case\">F<\/jats:styled-content>as expression may result in altered apoptosis and, ultimately, affect both the immune response and implantation; it is in fact associated with recurrent pregnancy loss, preterm premature rupture of membranes and pre\u2010eclampsia. Currently, there are over 500 cases of <jats:styled-content style=\"fixed-case\">ALPS<\/jats:styled-content> reported worldwide from various racial and ethnic backgrounds. Up to date, the published work contains no specific reports on pregnancy outcome in women affected by <jats:styled-content style=\"fixed-case\">ALPS<\/jats:styled-content>. We present a case of full\u2010term uneventful pregnancy in a patient affected by <jats:styled-content style=\"fixed-case\">ALPS<\/jats:styled-content>. A specific clinical follow\u2010up in a pregnant woman with primary immunologic disease is suggested.<\/jats:p>","DOI":"10.1111\/jog.12556","type":"journal-article","created":{"date-parts":[[2014,10,10]],"date-time":"2014-10-10T05:41:13Z","timestamp":1412919673000},"page":"460-463","source":"Crossref","is-referenced-by-count":2,"title":["Autoimmune lymphoproliferative syndrome in pregnancy: A case of favorable mother\u2013fetal outcome in a well\u2010controlled disease"],"prefix":"10.1111","volume":"41","author":[{"given":"Simona","family":"Patti","sequence":"first","affiliation":[{"name":"Department of Gynecology, Obstetrics and Urology Sapienza University of Rome  Rome Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppina","family":"Perrone","sequence":"additional","affiliation":[{"name":"Department of Gynecology, Obstetrics and Urology Sapienza University of Rome  Rome Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valentina","family":"De Pratti","sequence":"additional","affiliation":[{"name":"Department of Gynecology, Obstetrics and Urology Sapienza University of Rome  Rome Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isabella","family":"Quinti","sequence":"additional","affiliation":[{"name":"Department of Molecular Medicine Sapienza University of Rome  Rome Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cinzia","family":"Milito","sequence":"additional","affiliation":[{"name":"Department of Molecular Medicine Sapienza University of Rome  Rome Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roberto","family":"Brunelli","sequence":"additional","affiliation":[{"name":"Department of Gynecology, Obstetrics and Urology Sapienza University of Rome  Rome Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,10,10]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1080\/10245330500329094"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2010-04-280347"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2012.01.002"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0031-3955(05)70272-8"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.2006.05993.x"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-065X.1997.tb00967.x"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0301-2115(01)00431-6"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2009.10.026"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2005.05.082"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molmed.2007.05.005"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(67)80262-2"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/deg156"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.placenta.2003.11.007"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1521-4141(199811)28:11<3479::AID-IMMU3479>3.0.CO;2-U"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.2012.070524"}],"container-title":["Journal of Obstetrics and Gynaecology Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjog.12556","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjog.12556","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jog.12556","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T07:29:53Z","timestamp":1695540593000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1111\/jog.12556"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,10,10]]},"references-count":15,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2015,3]]}},"alternative-id":["10.1111\/jog.12556"],"URL":"https:\/\/doi.org\/10.1111\/jog.12556","archive":["Portico"],"relation":{},"ISSN":["1341-8076","1447-0756"],"issn-type":[{"value":"1341-8076","type":"print"},{"value":"1447-0756","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,10,10]]}}}