{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T18:18:12Z","timestamp":1793729892900,"version":"4.6.1"},"reference-count":12,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2014,10,20]],"date-time":"2014-10-20T00:00:00Z","timestamp":1413763200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2015,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>The use of prophylactic antibiotics for laparoscopy of uncomplicated gynecologic conditions is controversial. The aim of this study was to assess whether prophylactic antibiotics is necessary to prevent early postoperative infections and febrile morbidity in elective laparoscopic surgery for benign gynecologic conditions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and Methods<\/jats:title><jats:p>A total of 218 patients who underwent laparoscopy for uncomplicated gynecologic conditions were recruited into the study over a 1\u2010year period. Following recruitment into the study, they were divided into two groups (ratio 1:1). Patients were divided into either group <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content> (<jats:italic>n<\/jats:italic>\u2009=\u2009115) the therapy arm or group <jats:styled-content style=\"fixed-case\">B<\/jats:styled-content> (<jats:italic>n<\/jats:italic>\u2009=\u2009103) the placebo arm. Group <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content> patients received oral azithromycin 1\u2009g daily for 3 days (i.e. the day before, the day of and the day after the procedure) while group <jats:styled-content style=\"fixed-case\">B<\/jats:styled-content> received placebo therapy. Post\u2010procedural febrile and infection morbidity was analyzed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Morbidity was absent in 91.3% of patients in both groups <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">B<\/jats:styled-content>. The primary outcome measure of postoperative fever was present in eight patients from each group. The secondary outcome measure of postoperative infection was present in one patient from the group that did not receive prophylaxis (group <jats:styled-content style=\"fixed-case\">B<\/jats:styled-content>), who had a surgical site infection. There were no patients with urinary tract infection or pelvic inflammatory disease during the study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Antibiotics prophylaxis was not able to achieve statistically significant reduction in postoperative febrile or infective morbidity in laparoscopic gynecologic surgery for benign uncomplicated conditions.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jog.12560","type":"journal-article","created":{"date-parts":[[2014,10,21]],"date-time":"2014-10-21T00:45:52Z","timestamp":1413852352000},"page":"596-600","source":"Crossref","is-referenced-by-count":2,"title":["Analyzing the necessity of prophylactic antibiotic usage in laparoscopy for uncomplicated gynecologic conditions in <scp>S<\/scp>ri <scp>L<\/scp>anka"],"prefix":"10.1111","volume":"41","author":[{"given":"Y. Rajayana J.","family":"Jayarathna","sequence":"first","affiliation":[{"name":"Teaching Hospital Peradeniya  Peradeniya Sri Lanka"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sisira","family":"Ranaraja","sequence":"additional","affiliation":[{"name":"Teaching Hospital Peradeniya  Peradeniya Sri Lanka"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dulika S.","family":"Sumathipala","sequence":"additional","affiliation":[{"name":"Department of Anatomy Faculty of Medicine University of Colombo  Colombo Sri Lanka"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,10,20]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.324.7328.31"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006254-199609000-00023"},{"key":"e_1_2_7_4_1","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1177\/106002809002400401","article-title":"Reducing the duration of prophylactic antibiotic use through computer monitoring of surgical patients","volume":"24","author":"Evans RS","year":"1990","journal-title":"DICP"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s002689900583"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1074-3804(96)80011-9"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(99)70199-7"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1159\/000267322"},{"key":"e_1_2_7_9_1","first-page":"217","article-title":"Benefits of antibiotic prophylaxis in laparoscopic gynaecological surgery","volume":"26","author":"Sturlese E","year":"1999","journal-title":"Clin Exp Obstet Gynecol"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000109219.24211.30"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(82)90362-3"},{"key":"e_1_2_7_12_1","first-page":"227","article-title":"Laparoscopic procedures: The American Association of Gynecologic Laparoscopists' Membership Survey for 1975","volume":"18","author":"Phillips J","year":"1977","journal-title":"J Reprod Med"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1479-828X.2008.00908.x"}],"container-title":["Journal of Obstetrics and Gynaecology Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjog.12560","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjog.12560","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jog.12560","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T08:56:47Z","timestamp":1695545807000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1111\/jog.12560"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,10,20]]},"references-count":12,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2015,4]]}},"alternative-id":["10.1111\/jog.12560"],"URL":"https:\/\/doi.org\/10.1111\/jog.12560","archive":["Portico"],"relation":{},"ISSN":["1341-8076","1447-0756"],"issn-type":[{"value":"1341-8076","type":"print"},{"value":"1447-0756","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,10,20]]}}}