{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,9]],"date-time":"2026-05-09T01:14:14Z","timestamp":1778289254829,"version":"3.51.4"},"reference-count":18,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2014,10,27]],"date-time":"2014-10-27T00:00:00Z","timestamp":1414368000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2015,4]]},"abstract":"Abstract<\/jats:title>Aim<\/jats:title>The aim of this study is to determine whether psychiatric symptoms affect recurrence risk of hyperemesis gravidarum (HG<\/jats:styled-content>).<\/jats:p><\/jats:sec>Methods<\/jats:title>The study sample included 108 women with HG<\/jats:styled-content> treated with i.v. fluids in their first pregnancy. Women were divided into two groups based on recurrence of HG<\/jats:styled-content> in their second pregnancy. Participants submitted medical records and completed a survey regarding pregnancy characteristics and psychiatric symptoms. The \u03c72<\/jats:sup>\u2010test and Student's t<\/jats:italic>\u2010test were performed to compare the two groups.<\/jats:p><\/jats:sec>Results<\/jats:title>Eighty\u2010four women (71%) had a recurrence of HG<\/jats:styled-content> requiring i.v. fluid for dehydration, and were compared with 34 women (29%) who did not have a recurrence. There were no significant differences in obstetric history, although there was a trend toward greater time between first and second pregnancy in the recurrence group (P<\/jats:italic>\u2009=\u20090.08). There were no differences in pre\u2010existing psychiatric diagnoses including anxiety, depression, bipolar disorder, panic or eating disorders. Following the first HG<\/jats:styled-content> pregnancy, participants in both groups were well matched for all post\u2010traumatic stress symptoms.<\/jats:p><\/jats:sec>Conclusion<\/jats:title>This study is the first to analyze the relationship of psychiatric factors to risk of recurrence of HG<\/jats:styled-content>. No factors were identified that increase the risk of recurrence including stress symptoms following a HG<\/jats:styled-content> pregnancy. Psychological sequelae associated with HG<\/jats:styled-content> are probably a result of the physical symptoms of prolonged severe nausea and vomiting, medication and\/or hospitalization, and likely play no role in disease etiology.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jog.12592","type":"journal-article","created":{"date-parts":[[2014,10,27]],"date-time":"2014-10-27T06:09:37Z","timestamp":1414390177000},"page":"512-516","source":"Crossref","is-referenced-by-count":19,"title":["Psychiatric factors do not affect recurrence risk of hyperemesis gravidarum"],"prefix":"10.1111","volume":"41","author":[{"given":"Aromalyn","family":"Magtira","sequence":"first","affiliation":[{"name":"Department of Statistics University of California, Los Angeles Los Angeles California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frederic","family":"Paik Schoenberg","sequence":"additional","affiliation":[{"name":"Department of Statistics University of California, Los Angeles Los Angeles California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6534-3114","authenticated-orcid":false,"given":"Kimber","family":"MacGibbon","sequence":"additional","affiliation":[{"name":"Hyperemesis Education and Research Foundation Leesburg Virginia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Khalil","family":"Tabsh","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology University of California, Los Angeles Los Angeles California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marlena S.","family":"Fejzo","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology University of California, Los Angeles Los Angeles California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,10,27]]},"reference":[{"key":"e_1_2_6_2_1","volume-title":"Care of Women in US 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