{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T10:56:45Z","timestamp":1773313005399,"version":"3.50.1"},"reference-count":33,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2014,11,3]],"date-time":"2014-11-03T00:00:00Z","timestamp":1414972800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2015,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>Non\u2010<jats:styled-content style=\"fixed-case\">H<\/jats:styled-content>odgkin's lymphoma (<jats:styled-content style=\"fixed-case\">NHL<\/jats:styled-content>) is a rare malignancy that can affect women of all ages. The purpose of our study was to estimate the incidence, maternal and fetal outcomes of pregnancy\u2010associated non\u2010Hodgkin's lymphoma (<jats:styled-content style=\"fixed-case\">PANHL<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and Methods<\/jats:title><jats:p>We conducted a population\u2010based cohort study on all births identified in the Healthcare Cost and Utilization Project \u2013 Nationwide Inpatient Sample from 2003 to 2011. Disease incidence was calculated and logistic regression was used to estimate the adjusted effect of <jats:styled-content style=\"fixed-case\">NHL<\/jats:styled-content> on maternal and fetal outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 7\u2009917\u2009453 births, there were 427 cases of <jats:styled-content style=\"fixed-case\">PANHL<\/jats:styled-content> for an overall incidence of 5.39 per 100\u2009000 births, increasing from 4.44 per 100\u2009000 births to 7.17 per 100\u2009000 births over the 9\u2010year period. Relative to controls, <jats:styled-content style=\"fixed-case\">PANHL<\/jats:styled-content> was more common among <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>aucasians and women aged 25\u201334 years. Non\u2010specified <jats:styled-content style=\"fixed-case\">PANHL<\/jats:styled-content> was most commonly coded in &gt;81% of cases, with mycosis fungoides and <jats:styled-content style=\"fixed-case\">B<\/jats:styled-content>urkitt's lymphoma being the other two most common. After adjusting for baseline characteristics, women with <jats:styled-content style=\"fixed-case\">PANHL<\/jats:styled-content> were more likely to have pre\u2010eclampsia, odds ratio (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>) 1.57 (95% confidence interval [<jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>] 1.06\u20132.32), cesarean section, <jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content> 1.37 (95%<jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 1.13\u20131.67), preterm births <jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content> 2.50 (95%<jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 1.94\u20133.22), postpartum blood transfusions, <jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content> 2.73 (2.10\u20133.55), and infectious morbidity, <jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content> 2.81 (95%<jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 1.16\u20136.79). Maternal and fetal mortality rates were significantly increased among women with <jats:styled-content style=\"fixed-case\">PANHL<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The incidence of <jats:styled-content style=\"fixed-case\">PANHL<\/jats:styled-content> is increasing and is associated with an increased risk of maternal and neonatal morbidity and mortality, and as such, women with <jats:styled-content style=\"fixed-case\">PANHL<\/jats:styled-content> may best be managed in specialized centers.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jog.12597","type":"journal-article","created":{"date-parts":[[2014,11,3]],"date-time":"2014-11-03T10:12:37Z","timestamp":1415009557000},"page":"582-589","source":"Crossref","is-referenced-by-count":29,"title":["Incidence and outcomes of women with non\u2010<scp>H<\/scp>odgkin's lymphoma in pregnancy: A population\u2010based study on 7.9 million births"],"prefix":"10.1111","volume":"41","author":[{"given":"Amira","family":"El\u2010Messidi","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Royal Victoria Hospital McGill University  Montreal Quebec Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valerie","family":"Patenaude","sequence":"additional","affiliation":[{"name":"Centre for Clinical Epidemiology and Community Studies McGill University  Montreal Quebec Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haim Arie","family":"Abenhaim","sequence":"additional","affiliation":[{"name":"Centre for Clinical Epidemiology and Community Studies McGill University  Montreal Quebec Canada"},{"name":"Department of Obstetrics and Gynecology Jewish General Hospital McGill University  Montreal Quebec Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,11,3]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.11097"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(11)61348-2"},{"key":"e_1_2_6_4_1","first-page":"1077","volume-title":"Principles and Practice of Medical Therapy in Pregnancy","author":"Kuzel TB","year":"1992"},{"key":"e_1_2_6_5_1","volume-title":"The Motherisk Guide to Cancer in Pregnancy and Lactation: Motherisk","author":"Koren G","year":"2005"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hoc.2011.01.001"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/GRF.0b013e318236e68a"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.23281"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0142(19970301)79:5<1004::AID-CNCR17>3.0.CO;2-5"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(12)70589-2"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0889-8545(05)70011-5"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1271\/bbb.100359"},{"key":"e_1_2_6_13_1","first-page":"287","article-title":"Can pregnancy aggravate the course of non\u2010Hodgkin's lymphoma?","volume":"10","author":"Giovannini M","year":"1989","journal-title":"Eur J Gynaecol Oncol"},{"key":"e_1_2_6_14_1","first-page":"803","article-title":"Non\u2010Hodgkin's lymphoma in pregnancy. Three cases and review of the literature","volume":"109","author":"Ioachim HL","year":"1985","journal-title":"Arch Pathol Lab Med"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ctrv.2008.01.002"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2005.10.014"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(08)70032-9"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2009.23.2801"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI119001"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/14.11.2895"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(93)90016-C"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwf176"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1037\/0278-6133.27.1.43"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2013.49.8220"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1067\/S0002-9378(03)00537-4"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.semnephrol.2010.10.010"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2004.11.006"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.3109\/10428199409049697"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/IGC.0b013e3181daaf3e"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdn307"},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(04)01466-4"},{"key":"e_1_2_6_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/0090-8258(90)90363-P"},{"key":"e_1_2_6_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(11)70363-1"},{"key":"e_1_2_6_34_1","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwn119"}],"container-title":["Journal of Obstetrics and Gynaecology Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjog.12597","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjog.12597","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jog.12597","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T08:57:13Z","timestamp":1695545833000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1111\/jog.12597"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,11,3]]},"references-count":33,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2015,4]]}},"alternative-id":["10.1111\/jog.12597"],"URL":"https:\/\/doi.org\/10.1111\/jog.12597","archive":["Portico"],"relation":{},"ISSN":["1341-8076","1447-0756"],"issn-type":[{"value":"1341-8076","type":"print"},{"value":"1447-0756","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,11,3]]}}}