{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,7,29]],"date-time":"2024-07-29T00:24:15Z","timestamp":1722212655176},"reference-count":9,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2014,12,16]],"date-time":"2014-12-16T00:00:00Z","timestamp":1418688000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2015,6]]},"abstract":"Abstract<\/jats:title>Vaginal carcinoma is a rare gynecological malignancy that is usually treated by radiation therapy and\/or surgery combined with chemotherapy. Here, we report a case of invasive vaginal carcinoma in a young woman who underwent fertility\u2010sparing treatment involving neoadjuvant chemotherapy and conservative surgery. A 36\u2010year\u2010old non\u2010parous woman had a solid tumor in the vagina. Positron emission tomography\/computed tomography showed a tumor in the vagina with high FDG<\/jats:styled-content> uptake (SUV<\/jats:styled-content>\u2009=\u200917.33) but no metastatic lesions. The patient was diagnosed with vaginal squamous cell carcinoma, FIGO<\/jats:styled-content> stage I<\/jats:styled-content>, T1N0M0<\/jats:styled-content>. Because she wished to retain her fertility, neoadjuvant chemotherapy consisting of irinotecan hydrochloride and nedaplatin was initiated. After four courses of chemotherapy, partial vaginectomy was carried out and the pathological diagnosis of the residual lesion was VAIN<\/jats:styled-content> 3. Following two further courses of the same chemotherapy, she obtained complete response, and has shown no evidence of disease for 14 months.<\/jats:p>","DOI":"10.1111\/jog.12638","type":"journal-article","created":{"date-parts":[[2014,12,16]],"date-time":"2014-12-16T08:04:44Z","timestamp":1418717084000},"page":"989-992","source":"Crossref","is-referenced-by-count":6,"title":["Vaginal carcinoma in a young woman who underwent fertility\u2010sparing treatment involving chemotherapy and conservative surgery"],"prefix":"10.1111","volume":"41","author":[{"given":"Yasushi","family":"Mabuchi","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Wakayama Medical University School of Medicine Wakayama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tamaki","family":"Yahata","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Wakayama Medical University School of Medicine Wakayama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aya","family":"Kobayashi","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Wakayama Medical University School of Medicine Wakayama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuko","family":"Tanizaki","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Wakayama Medical University School of Medicine Wakayama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sawako","family":"Minami","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Wakayama Medical University School of Medicine Wakayama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuhiko","family":"Ino","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Wakayama Medical University School of Medicine Wakayama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,12,16]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21166"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0142(19980901)83:5<1033::AID-CNCR30>3.0.CO;2-6"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2013.02.004"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2013.08.012"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2008.07.005"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2006.02.032"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2005.05.007"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.3892\/or.2012.1814"},{"key":"e_1_2_5_10_1","first-page":"123","article-title":"Stage II vaginal cancer responding to chemotherapy with irinotecan and cisplatin: A case report","volume":"6","author":"Umesaki N","year":"1999","journal-title":"Oncol Rep"}],"container-title":["Journal of Obstetrics and Gynaecology Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjog.12638","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjog.12638","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jog.12638","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T21:38:35Z","timestamp":1696196315000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1111\/jog.12638"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,12,16]]},"references-count":9,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2015,6]]}},"alternative-id":["10.1111\/jog.12638"],"URL":"https:\/\/doi.org\/10.1111\/jog.12638","archive":["Portico"],"relation":{},"ISSN":["1341-8076","1447-0756"],"issn-type":[{"value":"1341-8076","type":"print"},{"value":"1447-0756","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,12,16]]}}}