{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T09:07:58Z","timestamp":1762506478016},"reference-count":20,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2014,12,10]],"date-time":"2014-12-10T00:00:00Z","timestamp":1418169600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2015,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>Management of atypical polypoid adenomyoma (<jats:styled-content style=\"fixed-case\">APAM<\/jats:styled-content>) is complicated because it can sometimes coexist with atypical endometrial hyperplasia (<jats:styled-content style=\"fixed-case\">AEH<\/jats:styled-content>) or endometrioid adenocarcinoma. It is often difficult to assess myometrial invasion in <jats:styled-content style=\"fixed-case\">APAM<\/jats:styled-content> complicated with endometrial cancer. We encountered three patients who, contrary to magnetic resonance imaging, did not have myometrial invasion on hysteroscopic transcervical resection (<jats:styled-content style=\"fixed-case\">TCR<\/jats:styled-content>) and therefore could have fertility preserved, and consequently could become pregnant.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We removed the polypoid lesion and a 3\u20135\u2009mm\u2010thick layer of the normal inner membrane at the root of the polypoid lesion, and then performed total curettage. Several pathological diagnostic procedures were then carried out on each of these resected specimens. Thereafter, high\u2010dose medroxyprogesterone acetate (<jats:styled-content style=\"fixed-case\">MPA<\/jats:styled-content>) was initiated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>All three patients underwent hysteroscopic transcervical tumor resection. The pathological diagnoses were as follows: patient 1, <jats:styled-content style=\"fixed-case\">G<\/jats:styled-content>1 endometrioid adenocarcinoma (<jats:styled-content style=\"fixed-case\">EMG1<\/jats:styled-content>)\u2009+\u2009<jats:styled-content style=\"fixed-case\">APAM<\/jats:styled-content>; patients 2,3, <jats:styled-content style=\"fixed-case\">AEH<\/jats:styled-content>\u2009+\u2009<jats:styled-content style=\"fixed-case\">APAM<\/jats:styled-content>. No findings of myometrial invasion in the resected root specimen were observed in any patient. In all cases, high\u2010dose <jats:styled-content style=\"fixed-case\">MPA<\/jats:styled-content> was initiated. After the disappearance of tumors, each patient achieved pregnancy. Complications such as placenta accreta were not observed at the time of delivery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In patients with <jats:styled-content style=\"fixed-case\">APAM<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">AEH<\/jats:styled-content> or <jats:styled-content style=\"fixed-case\">EMG1<\/jats:styled-content>, <jats:styled-content style=\"fixed-case\">TCR<\/jats:styled-content> may aid accurate diagnosis when myometrial invasion is unclear on diagnostic imaging.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jog.12645","type":"journal-article","created":{"date-parts":[[2014,12,10]],"date-time":"2014-12-10T10:57:05Z","timestamp":1418209025000},"page":"768-775","source":"Crossref","is-referenced-by-count":13,"title":["Hysteroscopic transcervical resection is useful to diagnose myometrial invasion in atypical polypoid adenomyoma coexisting with atypical endometrial hyperplasia or endometrial cancer with suspicious myometrial invasion"],"prefix":"10.1111","volume":"41","author":[{"given":"Wataru","family":"Yamagami","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Keio University School of Medicine  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nobuyuki","family":"Susumu","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Keio University School of Medicine  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomomi","family":"Ninomiya","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Keio University School of Medicine  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naoki","family":"Nakadaira","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Keio University School of Medicine  Tokyo 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