{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T16:40:36Z","timestamp":1762101636265},"reference-count":24,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2014,12,16]],"date-time":"2014-12-16T00:00:00Z","timestamp":1418688000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2015,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To evaluate whether the presence of amniotic components in the maternal uterine vasculature could be a specific pathological indicator for amniotic fluid embolism (<jats:styled-content style=\"fixed-case\">AFE<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Medical records of patients treated between <jats:styled-content style=\"fixed-case\">J<\/jats:styled-content>anuary 2006 and <jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>arch 2013 were retrospectively examined to identify patients who underwent post\u2010partum hysterectomy or autopsy due to maternal death. Three subjects with <jats:styled-content style=\"fixed-case\">AFE<\/jats:styled-content> with disseminated intravascular coagulation (<jats:styled-content style=\"fixed-case\">DIC<\/jats:styled-content>)\u2010type post\u2010partum hemorrhage (<jats:styled-content style=\"fixed-case\">PPH<\/jats:styled-content>), and 13 non\u2010<jats:styled-content style=\"fixed-case\">AFE<\/jats:styled-content> subjects were included in analysis. Histochemical staining using hematoxylin\u2013eosin (HE) and alcian blue, and immunohistochemical staining for sialyl\u2010<jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>n were conducted to detect amniotic components in the maternal uterine vasculature.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Alcian blue was positive for amniotic components in the uterine vasculature of all subjects with <jats:styled-content style=\"fixed-case\">AFE<\/jats:styled-content> and of several subjects without <jats:styled-content style=\"fixed-case\">AFE<\/jats:styled-content>. Similarly, HE and sialyl\u2010<jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>n were negative in some <jats:styled-content style=\"fixed-case\">AFE<\/jats:styled-content> subjects and positive in some non\u2010<jats:styled-content style=\"fixed-case\">AFE<\/jats:styled-content> subjects.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The presence of maternal intravascular fetal material is not a specific indicator for <jats:styled-content style=\"fixed-case\">AFE<\/jats:styled-content> with <jats:styled-content style=\"fixed-case\">DIC<\/jats:styled-content>\u2010type <jats:styled-content style=\"fixed-case\">PPH<\/jats:styled-content>. Therefore, the presence of fetal components in the uterine vasculature is unlikely to be a definitive indicator for <jats:styled-content style=\"fixed-case\">AFE<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jog.12650","type":"journal-article","created":{"date-parts":[[2014,12,16]],"date-time":"2014-12-16T08:29:47Z","timestamp":1418718587000},"page":"870-875","source":"Crossref","is-referenced-by-count":7,"title":["Amniotic components in the uterine vasculature and their role in amniotic fluid embolism"],"prefix":"10.1111","volume":"41","author":[{"given":"Hiroko","family":"Nakagami","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Saitama Medical University  Saitama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takeshi","family":"Kajihara","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Saitama Medical University  Saitama 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