{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,3]],"date-time":"2023-10-03T07:15:57Z","timestamp":1696317357970},"reference-count":25,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2015,12,2]],"date-time":"2015-12-02T00:00:00Z","timestamp":1449014400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2016,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>The aim of this study was to examine the association between maternal inherited bleeding disorders and neonatal complications.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and Methods<\/jats:title><jats:p>This was a historical cohort study. The rare inherited bleeding disorders (RIBD) group consisted of a total of 100 women suffering from inherited bleeding disorders, aged 20\u201345 years who experienced pregnancy. In the healthy control group, 200 age\u2010 and body mass index\u2010matched women were selected. Details of demographic and obstetric characteristics of the samples in both groups were collected using their medical records.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The mean ages of the women in the RIBD and healthy control groups were 32.6 (7.07) and 32.4 (7.3) years, respectively. No statistically significant differences were found in terms of age and other demographic characteristics of the women between the groups. The mean neonatal birthweight in the RIBD group was statistically lower than that in the healthy control group, 3018.2 (546.9)\u00a0g <jats:italic>vs<\/jats:italic> 3299.4 (456.8)\u00a0g, respectively (<jats:italic>P<\/jats:italic> = 0.021). The prevalence of low birthweight in the RIBD group was statistically higher in comparison to that in the healthy control group (<jats:italic>P<\/jats:italic> = 0.041).<\/jats:p><jats:p>After adjustment for potential confounders, it was found that maternal bleeding disorder had significant negative effects on birthweight in newborns (odds ratio, 1.05; 95% confidence interval, 1.01\u20133.43, <jats:italic>P<\/jats:italic> = 0.001). Those infants were statistically more likely to experience head bleeding, early hyperbilirubinemia and hospitalization than the healthy group (<jats:italic>P<\/jats:italic> = 0.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Maternal rare inherited bleeding disorders may have a devastating consequence for neonates.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jog.12884","type":"journal-article","created":{"date-parts":[[2015,12,2]],"date-time":"2015-12-02T10:42:37Z","timestamp":1449052957000},"page":"172-177","source":"Crossref","is-referenced-by-count":3,"title":["Maternal rare inherited bleeding disorders and neonatal complications"],"prefix":"10.1111","volume":"42","author":[{"given":"Samira","family":"Behboudi\u2010Gandevani","sequence":"first","affiliation":[{"name":"Reproductive Endocrine Research Center Research Institute of Endocrine Science, Shahid Beheshti University of Medical Science  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lida","family":"Moghaddam\u2010Banaem","sequence":"additional","affiliation":[{"name":"Department of Midwifery and Reproductive Health, Faculty of Medical Sciences Tarbiat Modares University  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shirin","family":"Shahbazi","sequence":"additional","affiliation":[{"name":"Department of Medical Genetics, Faculty of Medical Sciences Tarbiat Modares University  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fatemeh","family":"Ekhtesari","sequence":"additional","affiliation":[{"name":"Department of Midwifery and Reproductive Health, Faculty of Medical Sciences Tarbiat Modares University  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,12,2]]},"reference":[{"key":"e_1_2_7_2_1","first-page":"90","article-title":"Platelets in 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