{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T23:53:40Z","timestamp":1790898820898,"version":"4.1.0"},"reference-count":55,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2016,1,20]],"date-time":"2016-01-20T00:00:00Z","timestamp":1453248000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2016,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>Mercury, an environmental contaminant, is a risk factor for health in whole living organisms. In this study, we investigated whether mercury vapor (HgO) inhalation has an effect on rat ovary.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Twelve Wistar albino rats were divided equally into experimental (Hg) and control groups (<jats:italic>n<\/jats:italic>= 6). Animals in the Hg group were exposed to HgO for 45 days at a dose 1 mg\/m<jats:sup>3<\/jats:sup>\/day, after which, histological and stereological assessment were carried out.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Ovaries exposed to HgO had histo\u2010morphometric alterations. HgO inhalation resulted in reduction of the total number of primordial, primary and Graaf follicles. Also, mean volume of ovary, medulla and cortex, corpus luteum (c.\u00a0luteum) and Graaf follicles was decreased in the Hg group. Moreover, there was a significant increase in total volume of the atretic follicles. On light microscopy, thickening of tunica albuginea, increase of fibrils within the connective tissue, congestion of the capillaries and venous vessels, thinned walls and fibrin deposition in some large blood vessels, and edema were seen. Also, irregular follicle and oocyte borders, and hydropic degeneration in follicular granulosa cells were detected.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Structural alterations could be attributed to the toxic influence of HgO on rat ovary. The use of Hg should therefore be more controlled to minimize its toxic effect.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jog.12911","type":"journal-article","created":{"date-parts":[[2016,1,20]],"date-time":"2016-01-20T06:07:02Z","timestamp":1453270022000},"page":"410-416","source":"Crossref","is-referenced-by-count":31,"title":["Effect of mercury vapor inhalation on rat ovary: Stereology and histopathology"],"prefix":"10.1111","volume":"42","author":[{"given":"Berrin Zuhal","family":"Altunkaynak","sequence":"first","affiliation":[{"name":"Department of Histology and Embryology, Faculty of Medicine Ondokuz May\u0131s University Samsun Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nilgun","family":"Akg\u00fcl","sequence":"additional","affiliation":[{"name":"Departments of Restorative Dentistry, and Oral Diagnosis and Radiology, Faculty of Dentistry Atat\u00fcrk University Erzurum 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