{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,7,31]],"date-time":"2024-07-31T02:48:18Z","timestamp":1722394098589},"reference-count":26,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2016,1,20]],"date-time":"2016-01-20T00:00:00Z","timestamp":1453248000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Korea Healthcare Technology R&D Project, Ministry of Health& Welfare, Republic of Korea.","award":["A070001"],"award-info":[{"award-number":["A070001"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2016,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>We analyzed the N\u2010terminal pro\u2010B\u2010type natriuretic peptide (NT\u2010proBNP) and cardiac troponin T (cTnT) in non\u2010immune hydrops cases, to determine whether congestive heart failure or inadequate cardiac output may be mechanisms underlying abnormal fluid collection in hydrops.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The study population consisted of singleton neonates with non\u2010immune hydrops and healthy control neonates, matched for both gestational age at delivery and mode of delivery. The subjects were divided into three groups: group 1, hydrops of cardiac origin (n=6); group 2, hydrops of non\u2010cardiac origin (n=17); and group 3, control (n=23). The NT\u2010proBNP and cTnT were measured in the cord blood collected at the time of delivery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The median cord blood concentrations of NT\u2010proBNP and cTnT were not different between the hydrops (groups 1 and 2) or control cases. However, the NT\u2010proBNP level was elevated in group 1 compared with groups 2 and 3. The concentrations of cTnT did not differ among the three groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The concentration of NT\u2010proBNP was only elevated in cases of hydrops of cardiac origin. Congestive heart failure might not be the underlying mechanism of fluid collection in cases of non\u2010immune hydrops of non\u2010cardiac origin, and NT\u2010proBNP may be a promising tool to differentiate the origin of hydrops.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jog.12920","type":"journal-article","created":{"date-parts":[[2016,1,20]],"date-time":"2016-01-20T11:03:40Z","timestamp":1453287820000},"page":"380-384","source":"Crossref","is-referenced-by-count":7,"title":["N\u2010terminal pro\u2010B\u2010type natriuretic peptide and cardiac troponin T in non\u2010immune hydrops"],"prefix":"10.1111","volume":"42","author":[{"given":"Seung Mi","family":"Lee","sequence":"first","affiliation":[{"name":"Departments of Obstetrics and Gynecology Seoul National University College of Medicine  Seoul Korea"},{"name":"Department of Obstetrics and Gynecology Seoul Metropolitan Government Seoul National University Boramae Medical Center  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jong Kwan","family":"Jun","sequence":"additional","affiliation":[{"name":"Departments of Obstetrics and Gynecology Seoul National University College of Medicine  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Su Ah","family":"Kim","sequence":"additional","affiliation":[{"name":"Departments of Obstetrics and Gynecology Seoul National University College of Medicine  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Min Ji","family":"Kang","sequence":"additional","affiliation":[{"name":"Departments of Obstetrics and Gynecology Seoul National University College of Medicine  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sang Hoon","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine Seoul National University College of Medicine  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"JoonHo","family":"Lee","sequence":"additional","affiliation":[{"name":"Departments of Obstetrics and Gynecology Seoul National University College of Medicine  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chan\u2010Wook","family":"Park","sequence":"additional","affiliation":[{"name":"Departments of Obstetrics and Gynecology Seoul National University College of Medicine  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joong Shin","family":"Park","sequence":"additional","affiliation":[{"name":"Departments of Obstetrics and Gynecology Seoul National University College of Medicine  Seoul 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