{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T14:56:28Z","timestamp":1790088988942,"version":"4.0.1"},"reference-count":18,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2016,1,20]],"date-time":"2016-01-20T00:00:00Z","timestamp":1453248000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2016,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To identify whether an isolated single umbilical artery (ISUA) impacts pregnancy outcome and delivery mode in single and full\u2010term births.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective study was carried out on 93\u2009592 pregnant women (singleton pregnancy; full\u2010term birth; no known fetal chromosomal and structural anomalies) who gave birth between January 2011 and January 2012 in 39 hospitals within China. Pregnancy outcomes and modes of delivery were compared between research (313 cases with ISUAs) and comparison groups (1\u2009252 cases with three\u2010vessel cords in a 1:4 ratio randomly matched by parity).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The birth weights (3264.71 \u00b1 469.95 g vs 3340.76 \u00b1 434.25 g, <jats:italic>P<\/jats:italic> = 0.001), birth lengths (48.51\u00b1 2.84 cm vs 49.99\u00b1 1.65cm, <jats:italic>P<\/jats:italic> = 0.000), placental weights (511.31\u00b1 76.43 g vs 545.31\u00b1 85.06 g, <jats:italic>P<\/jats:italic> = 0.002), umbilical cord lengths (52.64 \u00b1 8.82 cm vs 54.08\u00b1 7.81cm, <jats:italic>P<\/jats:italic> = 0.002) and Apgar scores within one min of birth (8.83 \u00b1 0.96 vs 9.57 \u00b1 0.75, <jats:italic>P<\/jats:italic> = 0.000) of newborn infants were significantly lower in the research than the comparison group; the incidence of small for gestational age (10.94% vs 5.39%, <jats:italic>P<\/jats:italic> = 0.000) and low birth weight infants (6.69% vs 1.98%, <jats:italic>P<\/jats:italic> = 0.000) were significantly higher in the research group. There was no significant difference in fetal\/placental weight, incidence of velamentous cord insertions, 1 min Apgar score &lt; 7, 5 min Apgar score &lt; 7 or vaginal or emergency cesarean delivery rates as a result of fetal factors between the two groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>An ISUA is associated with an adverse pregnancy outcome; however does not decrease the rate of vaginal delivery in full\u2010term births.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jog.12921","type":"journal-article","created":{"date-parts":[[2016,1,20]],"date-time":"2016-01-20T12:02:36Z","timestamp":1453291356000},"page":"399-403","source":"Crossref","is-referenced-by-count":8,"title":["Impact of isolated single umbilical artery on pregnancy outcome and delivery in full\u2010term births"],"prefix":"10.1111","volume":"42","author":[{"given":"Nan","family":"Shen","sequence":"first","affiliation":[{"name":"Perinatal medicine department, Beijing Obstetrics and Gynecology Hospital Capital Medical University  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weiyuan","family":"Zhang","sequence":"additional","affiliation":[{"name":"Perinatal medicine department, Beijing Obstetrics and Gynecology Hospital Capital Medical University  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guanghui","family":"Li","sequence":"additional","affiliation":[{"name":"Perinatal medicine department, Beijing Obstetrics and Gynecology Hospital Capital Medical University  Beijing 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